Sodium tanshinone IIA sulfonate depresses angiotensin II-induced cardiomyocyte hypertrophy through MEK/ERK pathway

Experimental and Molecular Medicine

Volumn 39, Issue 1, 2007, Pages 65-73

  Yang, Le ^a   Zou, Xiaojing ^a   Liang, Qiansheng ^a   Chen, Hao ^b   Feng, Jun ^a   Yan, Li ^a   Wang, Zhaohua ^a   Zhou, Daixing ^a   Li, Shusheng ^a   Yao, Shanglong ^a   Zheng, Zhi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Angiotensin II; Extracellular signal regulated MAP kinases; Hypertrophy; Myocytes, cardiac; Tanshinone

Indexed keywords

ANGIOTENSIN II; ATRIAL NATRIURETIC FACTOR; EOSIN; HEMATOXYLIN; LEUCINE; MITOGEN ACTIVATED PROTEIN KINASE; SODIUM TANSHINONE 2A SULFONIC ACID; SULFONIC ACID DERIVATIVE; TANSHINONE; UNCLASSIFIED DRUG; UO 126;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SIZE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MORPHOMETRICS; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SYSTOLIC BLOOD PRESSURE;

RATTUS NORVEGICUS;

EID: 33847670191     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2007.8     Document Type: Article

References (38)

1. Baker KM, Aceto JF. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am J Physiol 1990;259:610-8
2. Bueno OF, De Windt LJ, Tymitz KM, Witt SA, Kimball TR, Klevitsky R, Hewett TE, Jones SP, Lefer DJ, Peng CF, Kitsis RN, Molkentin JD. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J 2000;19:6341-50
3. Chen W, Dong Y, Wang C, Ting G. Pharmacological studies of sodium tanshinone IIA sulfonate. Acta Pharmacol Sin 1979;14:277-83
4. Cohn JN, Ferrari R, Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf on an international forum on cardiac remodelling. J Am Coll Cardiol 2000;35:569-82
5. Dostal DE, Baker KM. The cardiac renin-angiotensin system: conceptual, or a regulator of cardiac function? Circ Res 1999;85:643-50
6. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM. Identification of a novel mitogen inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 1998;273:18623-32
7. Fischer TA, Ludwig S, Flory E, Gambaryan S, Singh K, Finn P, Pfeffer MA, Kelly RA, Pfeffer JM. Activation of cardiac c-Jun NH(2)-terminal kinases and p38-mitogen-activated protein kinases with abrupt changes in hemodynamic load. Hypertension 2001;37:1222-8
8. Force T, Bonventre JV. Growth factors and mitogen-activated protein kinases. Hypertension 1998;31:152-61
9. Frey N, Katus HA, Olson EN, Hill JA. Hypertrophy of the heart: a new therapeutic target? Circulation 2004;109:1580-9
10. Frias MA, Rebsamen MC, Gerber-Wicht C, Lang U. Prostaglandin E2 activates Stat3 in neonatal rat ventricular cardiomyocytes: A role in cardiac hypertrophy. Cardiovasc Res 2007;73:57-65
11. Hannan RD, Luyken J, Rothblum LI. Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes. J Biol Chem 1996;271:3213-20
12. Hayakawa H, Raij L. The link among nitric oxide synthase activity, endothelial function, and aortic and ventricular hypertrophy in hypertension. Hypertension 1997;29:235-41
13. Kagiyama S, Eguchi S, Inagami T, Zhang YC, Phillips MI. Angiotensin II-induced cardiac hypertrophy and hypertension are attenuated by epidermal growth factor receptor antisense. Circulation 2002;106:909-12
14. Kennedy RA, Kemp TJ, Sugden PH, Clerk A. Using U0126 to dissect the role of the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade in the regulation of gene expression by endothelin-1 in cardiac myocytes. J Mol Cell Cardiol 2006;41:236-47
15. Kim L, Lee T, Fu J, Ritchie ME. Characterization of MAP kinase and PKC isoform and effect of ACE inhibition in hypertrophy in vivo. Am J Physiol 1999;277:1808-16
16. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990;322:1561-6
17. Lijnen P, Petrov V. Renin-Angiotensin System, Hypertrophy and Gene Expression in Cardiac Myocytes. J Mol Cell Cardiol 1999;31:949-70
18. Maller JL. Signal transduction: fishing at the cell surface. Science 2003;300:594-5
19. Miao CY, Tao X, Gong K, Zhang SH, Chu ZX, Su DF. Arterial remodeling in chronic sinoaortic-denervated rats. J Cardiovasc Pharmacol 2001;37:6-15
20. Miyazaki H, Shibata T, Fujii N. Intracellular signaling pathways of angiotensin II receptor type I involved in the development of cardiovascular diseases. Nippon Rinsho 1998;56:1906-11
21. Pinzar E, Wang T, Garrido MR, Xu W, Levy P, Bottari SP. Angiotensin II induces tyrosine nitration and activation of ERK1/2 in vascular smooth muscle cells. FEBS Letters 2005;579:5100-4
22. Ptashne M, Gann A. Signal transduction: imposing specificity on kinases. Science 2003;299:1025-7
23. Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes. Biochem Biophys Res Commun 1999;259:8-14
24. Sen S. Regression of cardiac hypertrophy. Experimental animal model. Am J Med 1983;75:87-93
25. Shih NL, Cheng TH, Loh SH, Cheng PY, Wang DL, Chen YS, Liu SH, Liew CC, Chen JJ. Reactive oxygen species modulate angiotensin II-induced beta-myosin heavy chain gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in neonatal rat cardiomyocytes. Biochem Biophys Res Commun 2001;283:143-8
26. Solit DB, Garraway LA, Pratilas CA, Sawai A, Getz G, Basso A, Ye Q, Lobo JM, She Y, Osman I, Golub TR, Sebolt-Leopold J, Sellers WR, Rosen N. BRAF mutation predicts sensitivity to MEK inhibition. Nature 2005;439:358-62
27. Sugden PH. Signalling pathways in cardiac myocyte hypertrophy. Ann Med 2001;33:611-22
28. Sven W, Georg N. The role of the AT1 receptor in the cardiovascular continuum. Eur Heart J Suppl 2004;6:h3-h9
29. Takahashi K, Ouyang X, Komatsu K, Nakamura N, Hattori M, Baba A, Azuma J. Sodium tanshinone IIA sulfonate derived from Danshen (Salvia miltiorrhiza) attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac cells. Biochem Pharmacol 2002;64:745-50
30. Takeishi Y, Huang Q, Abe J, Glassman M, Che W, Lee JD, Kawakatsu H, Lawrence EG, Hoit BD, Berk BC, Walsh RA. Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch. J Mol Cell Cardiol 2001;33:1637-48
31. Tang W, Eisenbrand G. Salvia miltiorrhiza Bge. Chinese drugs of plant origin, 1992, 891-902, Springer, Berlin, Germany
32. Tao J, Wang QZ, Liu QY. Experimental study on prevent effect of tanshinone on injury of ischemia-reperfusion of heart. Acta Anaesthesiol Sin 1996;16:202-4
33. Thorburn J, Carlson M, Mansour SJ, Chien KR, Ahn NG, Thorburn A. Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase. Mol Biol Cell 1995;6:1479-90
34. Wassmann S, Nickenig G. The role of the AT1 receptor in the cardiovascular continnum. Eur Heart J 2004;6:h3-h9
35. Wollert KC, Studer R, von Bulow B, Drexler H. Survival after myocardial infarction in the rat. Role of tissue angiotensin-converting enzyme inhibition. Circulation 1994;90:2457-67
36. Yamazaki T, Komuro I, Kudoh S, Zou Y, Shiojima I, Mizuno T, Takano H, Hiroi Y, Ueki K, Tobe K, Kadowaki T, Yazaki Y. Angiotensin II partly mediates mechanical stress-induced cardiac hypertrophy. Circ Res 1995;77:258-65
37. Yue TL, Gu JL, Wang C, Reith AD, Lee JC, Mirabile RC, Kreutz R, Wang Y, Maleeff B, Parsons AA, Ohlstein EH. Extracellular signal-regulated kinase plays an essential role in hypertrophic agonists, endothelin-1 and phenylephrine-induced cardiomyocyte hypertrophy. J Biol Chem 2000;275:37895-901
38. Zhao BL, Jiang W, Zhao Y, Hou JW, Xin WJ. Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemiareperfusion injury. Biochem Mol Biol Int 1996;38:1171-82