Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF- κB: Inhibitory role of curcumin

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 2, 2009, Pages

  Binion, David G ^a   Heidemann, Jan ^b   Li, Mona S ^c   Nelson, Victoria M ^c   Otterson, Mary F ^c   Rafiee, Parvaneh ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Mitogen activated protein kinase; Nuclear factor B; Phosphatidylinositol 3 kinase; Protein kinase B

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA TOCOPHEROL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; SMALL INTERFERING RNA; SN 50; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CONTROLLED STUDY; DRUG TARGETING; ENDOTHELIUM CELL; ENTERITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; INFLAMMATION; INTESTINE CELL; LEUKOCYTE ADHERENCE; MICROVASCULATURE; NUCLEOTIDE SEQUENCE; PHYSIOLOGICAL STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTIVE TRANSPORT, CELL NUCLEUS; CELL ADHESION; CELLS, CULTURED; CURCUMIN; ENDOTHELIAL CELLS; GASTROINTESTINAL AGENTS; HUMANS; IMMUNOGLOBULINS; INTESTINES; LEUKOCYTES; LIPOPOLYSACCHARIDES; MICROVESSELS; MUCOPROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR CELL ADHESION MOLECULE-1;

EID: 68049083799     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00087.2009     Document Type: Article

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