Progress in the study of brain tumor stem cells as treatment targets

Brain and Nerve

Volumn 61, Issue 7, 2009, Pages 781-789

  Hide, Takuichiro ^a   Kuratsu, Jun Ichi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Brain tumor stem cell; Cancer stem cell; Neural stem cell; Niche; Treatment

Indexed keywords

BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER RESEARCH; CANCER STEM CELL; CANCER THERAPY; DENTATE GYRUS; GLIOBLASTOMA; HUMAN; LATERAL BRAIN VENTRICLE; NEURAL STEM CELL; NONHUMAN; RADIOSENSITIVITY; REVIEW; SUBVENTRICULAR ZONE; SURVIVAL TIME; TUMOR RECURRENCE; XENOGRAFT;

ADULT; ANIMALS; BRAIN NEOPLASMS; CEREBRAL VENTRICLES; DENTATE GYRUS; GLIOBLASTOMA; HIPPOCAMPUS; HUMANS; MICE; NEOPLASTIC STEM CELLS; STEM CELL NICHE;

EID: 67849086474     PISSN: 18816096     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (35)

1. Till JE, McCulloch EA: A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res 14: 213-222, 1961
2. Bonnet D, Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730-737, 1997 (Pubitemid 27298715)
3. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF: Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 100: 3983-3988, 2003 (Pubitemid 36418143)
4. Singh SK, Clarke ID, Terasaki M, Bonn VE, Hawkins C, et al: Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828, 2003 (Pubitemid 37187480)
5. Reynolds BA, Weiss S: Generation of neurons and astrocytes from isolated cells of adult mammalian central nervous system. Science 255: 1707-1710, 1992
6. Yin AH, Miraglia S, Zanjani ED, Almedia-Porada G, Ogawa M, et al: AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 90: 5002-5012, 1997 (Pubitemid 28007217)
7. Uchida N, Buck DW, He D, Reitsma MJ, Masek M, et al: Direct isolation of human central nervous system cells. Proc Natl Acad Sci U S A 97: 14720-14725, 2000 (Pubitemid 32016642)
8. Singh SK, Howkins C, Clarke ID, Squire JA, Bayani J, et al: Identification of human brain tumour initiating cells. Nature 432: 396-401, 2004 (Pubitemid 39551674)
9. Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, et al: Radial glial cells are candidate stem cells of ependymoma. Cancer Cell 8: 323-335, 2005 (Pubitemid 41443417)
10. Yi L, Zhou ZH, Ping YF, Chen JH, Yao XH, et al: Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma. Mod Pathol 20: 1061-1068, 2007 (Pubitemid 47429200)
11. Bunting KD: ABC transporters as phenotypic markers and functional regulators of stem cell. Stem Cells 20: 11-20, 2002
12. Kondo T, Setoguchi T, Taga T: Persistence of small subpopulation of cancer stem-like cells in C6 glioma cell lines. Proc Natl Acad Sci U S A 101: 781-786, 2004 (Pubitemid 38121035)
13. Rebetz J, Tian D, Persson A, Widegren B, Salford LG, et al: Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma. PLoS ONE 3: e1936, 2008 (Pubitemid 351984112)
14. Zeppernick F, Ahmadi R, Campos B, Dictus C, Helmke BM, et al: Stem cell marker CD133 affects clinical outcome in glioma patients. Clin Cancer Res 14: 123-129, 2008
15. Strojnik T, Rosland GV, Sakariassen PO, Kavalar R, Lah T: Neural stem cell markers, nestin and musashi protein, in the progression of human glioma: correlation of nestin with prognosis of patient survival. Surg Neurol 68: 133-144, 2007 (Pubitemid 47087905)
16. Jaksch M, Múnera J, Bajpai R, Terskikh A, Oshima RG: Cell cycle-dependent variation of a CD133 epitope in human embryonic stem cell, colon cancer and melanoma cell lines. Cancer Res 68, 7882-7886, 2008
17. - glioblastoma- derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res 67: 4010-4015, 2007 (Pubitemid 46815044)
18. Ogden AT, Waziri AE, Lochhead RA, Fusco D, Lopez K, et al: Identification of A2B5+CD133- tumor- initiating cells in adult human gliomas. Neurosurgery 62: 505-515, 2008
19. Yi JM, Tsai HC, Glöckner SC, Lin S, Ohm JE, et al: Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Res 68, 8094-8103, 2008
20. Schofield R: The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4: 7-25, 1978 (Pubitemid 8376317)
21. Shen Q, Goderie SK, Jin L, Karanth N, Sun Y, et al: Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 304: 1338-1340, 2004 (Pubitemid 38697433)
22. Palma V, Lim DA, Dahmane N, Sanchez P, Brionne TC, et al: Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development 132: 335-344, 2005 (Pubitemid 40268283)
23. Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, et al: A perivascular niche for brain tumor stem cells. Cancer Cell 11: 69-82, 2007 (Pubitemid 46054518)
24. Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, et al: Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444: 756-760, 2006 (Pubitemid 44949604)
25. Liu G, Yuan X, Zeng Z, Tunici P, Ng H, et al: Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer 5: 67, 2006 (Pubitemid 44942887)
26. Nandi S, Ulasov IV, Tyler MA, Sugihara AQ, Molinero L, et al: Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells. Cancer Res 68: 5778-5784, 2008
27. Varghese M, Olstorn H, Sandberg C, Vik-Mo EO, Noordhuis P, et al: A comparison between stem cells from the adult human brain and from brain tumors. Neurosurgery 63: 1022-1034, 2008
28. Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, et al: Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996, 2005 (Pubitemid 40349501)
29. Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz i Altaba A: HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self- renewal, and tumorigenicity. Curr Biol 17: 165-172, 2007 (Pubitemid 46107823)
30. Fan X, Matsui W, Khaki L, Stearns D, Chun J, et al: Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res 66: 7445-7452, 2006 (Pubitemid 44289197)
31. Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, et al: Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells. J Biol Chem 283: 10958-10966, 2008
32. Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, et al: Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumor- initiating cells. Nature 444: 761-765, 2006 (Pubitemid 44949605)
33. Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, et al: Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Res 66: 7843-7848, 2006 (Pubitemid 44299144)
34. Kaplan RS, Riba R, Zacharoulis S, Bramley AH, Vincent L, et al: VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 438: 820-827, 2005 (Pubitemid 41753060)
35. Kobayashi S, Boggon TJ, Dayaram T, Jänne PA, Kocher O, et al: EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med 352: 786-792, 2005 (Pubitemid 40271173)