Mechanistic insights into the rhodium-catalyzed intramolecular ketone hydroacylation

Journal of the American Chemical Society

Volumn 131, Issue 3, 2009, Pages 1077-1091

  Shen, Zengming ^a   Dornan, Peter K ^a   Khan, Hasan A ^a   Woo, Tom K ^b   Dong, Vy M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

[CARBONYL; AS-LIGANDS; BOND FORMING; C-H BOND; CH-BOND ACTIVATION; CHIRAL LIGAND; DECARBONYLATION; DENSITY FUNCTIONAL THEORY CALCULATIONS; DETAILED KINETICS; DOUBLE BONDS; ENANTIOMERIC EXCESS; ENERGY TRANSITION STATE; EXPERIMENTAL DATA; HAMMETT PLOTS; HYDROACYLATION; INDUCTION PERIODS; INTRAMOLECULAR HYDROACYLATION; KINETIC ISOTOPE EFFECTS; KINETICS SIMULATIONS; LIMITING STEP; LONE PAIR; MECHANISTIC PATHWAYS; MODEL-BASED; OXIDATIVE ADDITIONS; PRECATALYST; PRODUCT INHIBITION; REDUCTIVE ELIMINATION; RHODIUM CARBONYL SPECIES; RHODIUM HYDRIDES; RHODIUM-CATALYZED; SEGPHOS; THEORETICAL STUDY; TRANSITION STATE STRUCTURE; TRANSITION-STATE;

ALDEHYDES; CARBONYLATION; CHEMICAL BONDS; DENSITY FUNCTIONAL THEORY; ISOTOPES; KETONES; LIGANDS; OXYGEN; PROPANE; SIMULATORS;

RHODIUM;

1,3 BIS (DIPHENYLPHOSPHINO) PROPANE; ALDEHYDE; CARBON; DIPHOSPHINE; HYDROGEN; KETONE; PROPANE; RHODIUM; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CARBONYLATION; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; COMPUTER SIMULATION; DENSITY FUNCTIONAL THEORY; DISSOCIATION CONSTANT; ENERGY ABSORPTION; ISOTOPE ANALYSIS; NUCLEAR MAGNETIC RESONANCE; OXIDATION KINETICS;

EID: 67749119978     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja806758m     Document Type: Article

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