Dietary Ascophyllum nodosum increases urinary excretion of tricarboxylic acid cycle intermediates in male Sprague-Dawley rats

Journal of Nutrition

Volumn 139, Issue 8, 2009, Pages 1487-1494

  Simmons Boyce, Joanne L ^a   Purcell, Sara L ^b,c   Nelson, Carolanne M ^b   MacKinnon, Shawna L ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^c UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ACETIC ACID; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CITRIC ACID; CREATININE; MALONIC ACID; MANNITOL; SUCCINIC ACID; TAURINE; TRIMETHYLAMINE; TRIMETHYLAMINE OXIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASCOPHYLLUM; ASCOPHYLLUM NODOSUM; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CITRIC ACID CYCLE; CONTROLLED STUDY; CREATININE URINE LEVEL; DIETARY FIBER; DIETARY INTAKE; ENZYME BLOOD LEVEL; FOOD INTAKE; INGESTION; MALE; METABOLISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRINCIPAL COMPONENT ANALYSIS; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SEAWEED; SPRAGUE DAWLEY RAT; URINALYSIS; URINARY EXCRETION; WEIGHT GAIN;

ANIMALS; ASCOPHYLLUM; CARBOXYLIC ACIDS; CITRIC ACID CYCLE; DIETARY FIBER; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MANNITOL; METABOLOMICS; PHENOLS; PLANT PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY;

ASCOPHYLLUM NODOSUM; MAMMALIA; RATTUS;

EID: 67749114245     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.109.107920     Document Type: Article

References (55)

1. Jensen A. Present and future needs for algae and algal products. Hydrobiologia. 1993;260-1:15-23.
2. Smit AJ. Medicinal and pharmaceutical uses of seaweed natural products: a review. J Appl Phycol. 2004;16:245-62.
3. König GM, Wright AD. Algal secondary metabolites and their pharmaceutical potential. In: Kinghorn AD, Balandrin MF, editors. Human medicinal agents from plants. Washington (DC): American Chemical Society; 1993. p. 276-93.
4. Haugan JA, Liaaen-Jensen S. Algal carotenoids 54. Carotenoids of brown algae (Phaeophyceae). Biochem Syst Ecol. 1994;22:31-41.
5. Blunt JW, Copp BR, HuW-P, Munro MHG, Northcote PT, Prinsep MR. Marine natural products. Nat Prod Rep. 2008;25:35-94.
6. Rangeley RW. The effects of seaweed harvesting on fishes: a critique. Environ Biol Fishes. 1994;39:319-28.
7. Moen E, Horn S, Østgaard K. Biological degradation of Ascophyllum nodosum. J Appl Phycol. 1997;9:347-57.
8. Anderson MJ, Blanton JR Jr, Gleghorn J, Kim SW, Johnson JW. Ascophyllum nodosum supplementation strategies that improve overall carcass merit of implanted English crossbred cattle. Asian-australas J Anim Sci. 2006;19:1514-8.
9. MacArtain P, Gill CIR, Brooks M, Campbell R, Rowland IR. Nutritional value of edible seaweeds. Nutr Rev. 2007;65:535-43.
10. Sharp GJ. Ascophyllum nodosum and its harvesting in Eastern Canada. In: Case studies of seven commercial seaweed resources. FAO Technical Report. 1986;281:3-46.
11. Gibney MJ, Walsh M, Brennan L, Roche HM, German B, van Ommen B. Metabolomics in human nutrition: opportunities and challenges. Am J Clin Nutr. 2005;82:497-503.
12. Lindon JC, Nicholson JK, Holmes E, Everett JR. Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts Magn Reson. 2000;12:289-320.
13. 1H NMR-based metabonomic approach. J Nutr. 2007;137:923-9.
14. van Dorsten FA, Daykin CA, Mulder TPJ, van Duynhoven JPM. Metabonomics approach to determine metabolic differences between green tea and black tea consumption. J Agric Food Chem. 2006; 54:6929-38.
15. 1H NMR-based metabonomic techniques in nutrition research: metabolic effects of dietary isoflavones in humans. J Nutr Biochem. 2005;16:236-44.
16. Nicholson JK, Connelly J, Lindon JC, Holmes E. Metabonomics: a platform for studying drug toxicity and gene function. Nat Rev Drug Discov. 2002;1:153-61.
17. Wang Y, Huiru T, Nicholson JK, Hylands PJ, Sampson J, Holmes E. A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion. J Agric Food Chem. 2005;53:191-6.
18. Solanky KS, Bailey NJ, Holmes E, Lindon JC, Davis AL, Mulder TP, Van Duynhoven JPM, Nicholson JK. NMR-based metabonomic studies on the biochemical effects of epicatechin in rats. J Agric Food Chem. 2003;51:4139-45.
19. Daykin CA, Van Duynhoven JP, Groenewegen A, Dachtler M, Van Amelsvoort JM, Mulder TP. Nuclear magnetic resonance spectroscopic based studies of the metabolism of black tea polyphenols in humans. J Agric Food Chem. 2005;53:1428-34.
20. Fardet A, Llorach R, Orsoni A, Martin J, Pujos-Guillot E, Lapierre C, Scalbert A. Metabolomics provide new insight on the metabolism of dietary phytochemicals in rats. J Nutr. 2008;138:1282-7.
21. Reeves PG. Components of the AIN-93 diets as improvements in the AIN-76A diet. J Nutr. 1997;127:S838-41.
22. Lindon JC, Nicholson JK, Everett JR. NMR spectroscopy of biofluids. Ann Rep NMR Spectrosc. 1999;38:1-88.
23. 13C NMR spectroscopy of human blood plasma. Anal Chem. 1995;67:793-811.
24. Eriksson L, Johansson E, Kettaneh-Wold N, Trygg J, Wikström C, Wold S. Multi- and megavariate data analysis: part 1. Basic principles and applications. Umeå (Sweden): Umetrics; 2006.
25. Trachtman H, Sturman JA. Taurine: a therapeutic agent in experimental kidney disease. Amino Acids. 1996;11:1-13.
26. Bell JD, Sadler PJ, Morris VC, Levander OA. Effect of aging and diet on proton NMR spectra of rat urine. Magn Reson Med. 1991;17:414-22.
27. 1H NMR and HPLC-TOF MS. Mol Biosyst. 2005; 1:166-75.
28. Schnackenberg LK, Sun J, Espandiari P, Holland RD, Hanig J, Beger RD. Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. BMC Bioinformatics 2007 [cited 2008 Jan 28];8 Suppl 7:S3. Available from: http://www.biomedcentral.com/1471-2105-8-S7- S3.
29. 1H NMR spectroscopy of urine and pattern recognition. Anal Biochem. 2001;295:194-202.
30. Gavaghan CL, Wilson ID, Nicholson JK. Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA. FEBS Lett. 2002;530:191-6.
31. Denton RM, Randle PJ, Bridges BJ, Cooper RH, Kerbey AL, Pask HT, Severson DL, Stransbie D, Whitehouse S. Regulation of mammalian pyruvate dehydrogenase. Mol Cell Biochem. 1975;9:27-53.
32. Penniston KL, Steele TH, Nakada SY. Lemonade therapy increases urinary citrate and urine volumes in patients with recurrent calcium oxalate stone formation. Urology. 2007;70:856-60.
33. Rudman D, Dedonis JL, Fountain MT, Chandler JB, Gerron GG, Fleming GA, Kutner MH. Hypocitraturia in patients with gastrointestinal malabsorption. N Engl J Med. 1980;303:657-61.
34. Guneral F, Bachmann C. Age-related reference values for urinary organic acids in a healthy Turkish pediatric population. Clin Chem. 1994;40:862-8.
35. Dumas ME, Barton RH, Toye A, Cloarec O, Blancher C, Rothwell A, Fearnside J, Tatoud R, Blanc V, et al. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci USA. 2006;103:12511-6.
36. Bhakuni DS, Rawat DS. Bioactive marine natural products. New York: Springer; 2005. p. 2-25.
37. Zhang AQ, Mitchell SC, Smith RL. Dietary precursors of trimethylamine in man: a pilot study. Food Chem Toxicol. 1999;37:515-20.
38. DaSilva E, Jensen A. Benthic marine and blue-green algal species as a source of choline. J Sci Food Agric. 1973;24:855-61.
39. Blunden G, Gordon SM, Smith BE, Fletcher RL. Quaternary ammonium compounds in species of the Fucaceae (Phaeophyceae) from Britain. Br. Eur Phycol J. 1985;20:105-8.
40. Zeisel SH, daCosta KA, Youssef M, Hensey S. Conversion of dietary choline to trimethylamine and dimethylamine in rats: dose-response relationship. J Nutr. 1989;119:800-4.
41. Craig SA. Betaine in human nutrition. Am J Clin Nutr. 2004;80:539-49.
42. Blunden G, Currie M, Mathe J, Hohmann J, Critchley A. Variations in betaine yields from marine algal species commonly used in the preparation of seaweed extracts used in agriculture. The Phycologist. 2009; 76:14.
43. Michel C, Macfarlane GT. Digestive fates of soluble polysaccharides from marine macroalgae: involvement of the colonic microflora and physiological consequences for the host. J Appl Bacteriol. 1996;80:349-69.
44. Kuda T, Yano T, Matsuda N, Nishizawa M. Inhibitory effects of laminaran and low molecular alginate against the putrefactive compounds produced by intestinal microflora in vitro and in rats. Food Chem. 2005;91:745-9.
45. Dierick N, Ovyn A, De Smet S. Effect of feeding intact brown seaweed Ascophyllum nodosum on some digestive parameters and on iodine content in edible tissues in pigs. J Sci Food Agric. 2009;89:584-94.
46. Mäkinen KK, Hämäläinen M. Metabolic effects in rats of high oral doses of galactitol, mannitol and xylitol. J Nutr. 1985;115:890-9.
47. Dills WL Jr. Sugar alcohols as bulk sweeteners. Annu Rev Nutr. 1989; 9:161-86.
48. Wiggins HS. Nutritional value of sugars and related compounds undigested in the small gut. Proc Nutr Soc. 1984;43:69-75.
49. Nicholson JK, Wilson ID. Understanding 'global' systems biology: metabonomics and the continuum of metabolism. Nat Rev Drug Discov. 2003;2:668-76.
50. Manach C, Williamson G, Morand C, Scalbert A, Rémésy C. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr. 2005;81 Suppl:S230-42.
51. Shibata T, Yamaguchi K, Nagayama K, Kawaguchi S, Nakamura T. Inhibitory activity of brown algal phlorotannins against glycosidases from the viscera of the turban shell Turbo cornutus. Eur J Phycol. 2002;37:493-500.
52. Waterfield CJ, Turton JA, Scales MD, Timbrell JA. Investigations into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats. Arch Toxicol. 1993;67:244-54.
53. Giboney PT. Mildly elevated liver transaminase levels in the asymptomatic patient. Am Fam Physician. 2005;71:1105-10.
54. Hatch MD, Stumpf PK. Fat metabolism in higher plants. XVII. Metabolism of malonic acid and its α-substituted derivatives in plants. Plant Physiol. 1962;37:121-6.
55. Targett NM, Arnold TM. Predicting the effects of brown algal phlorotannins on marine herbivores in trpical and temperate oceans. J Phycol. 1998;34:195-205.