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Volumn 34, Issue 3, 2009, Pages 424-427

Exercise, PGC-1α, and metabolic adaptation in skeletal muscle

Author keywords

Angiogenesis; Exercise; Fiber type transformation; Mitochondrial biogenesis; p38 mitogen activated protein kinase; Peroxisome proliferator activated receptor coactivator 1 ; Signal transduction; Skeletal muscle; Transcription

Indexed keywords

PPARGC1A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

EID: 67651211228     PISSN: 17155312     EISSN: None     Source Type: Journal    
DOI: 10.1139/H09-030     Document Type: Review
Times cited : (26)

References (43)
  • 1
    • 6044234749 scopus 로고    scopus 로고
    • 2+/ calmodulin-dependent protein kinase IV-deficient mice
    • doi:10.1152/ajpcell. 00248.2004. PMID:15229108
    • 2+/ calmodulin-dependent protein kinase IV-deficient mice. Am. J. Physiol. Cell Physiol. 287: C1311-C1319. doi:10.1152/ajpcell. 00248.2004. PMID:15229108.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.287
    • Akimoto, T.1    Ribar, T.J.2    Williams, R.S.3    Yan, Z.4
  • 2
    • 4143058006 scopus 로고    scopus 로고
    • Real-time imaging of peroxisome proliferator-activated receptor-γ coactivator-1α promoter activity in skeletal muscles of living mice
    • doi:10.1152/ajpcell.00425.2003. PMID:15151904
    • Akimoto, T., Sorg, B.S., and Yan, Z. 2004. Real-time imaging of peroxisome proliferator-activated receptor-γ coactivator-1α promoter activity in skeletal muscles of living mice. Am. J. Physiol. Cell Physiol. 287: C790-C796. doi:10.1152/ajpcell.00425.2003. PMID:15151904.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.287
    • Akimoto, T.1    Sorg, B.S.2    Yan, Z.3
  • 3
    • 21244477127 scopus 로고    scopus 로고
    • Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway
    • doi:10. 1074/jbc.M408862200. PMID:15767263
    • Akimoto, T., Pohnert, S.C., Li, P., Zhang, M., Gumbs, C., Rosenberg, P.B., et al. 2005. Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway. J. Biol. Chem. 280: 19587-19593. doi:10. 1074/jbc.M408862200. PMID:15767263.
    • (2005) J. Biol. Chem. , vol.280 , pp. 19587-19593
    • Akimoto, T.1    Pohnert, S.C.2    Li, P.3    Zhang, M.4    Gumbs, C.5    Rosenberg, P.B.6
  • 4
    • 52749095883 scopus 로고    scopus 로고
    • Functional interaction of regulatory factors with the Pgc-1α promoter in response to exercise by in vivo imaging
    • doi:10.1152/ajpcell.00104.2008. PMID:18434626
    • Akimoto, T., Li, P., and Yan, Z. 2008. Functional interaction of regulatory factors with the Pgc-1α promoter in response to exercise by in vivo imaging. Am. J. Physiol. 295: C288-C292. doi:10.1152/ajpcell.00104.2008. PMID:18434626.
    • (2008) Am. J. Physiol. , vol.295
    • Akimoto, T.1    Li, P.2    Yan, Z.3
  • 5
    • 22144434964 scopus 로고    scopus 로고
    • Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle
    • doi:10.1016/j.cmet.2005.03.002. PMID:16054070
    • Arany, Z., He, H., Lin, J., Hoyer, K., Handschin, C., Toka, O., et al. 2005. Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle. Cell Metab. 1: 259-271. doi:10.1016/j.cmet.2005.03.002. PMID:16054070.
    • (2005) Cell Metab. , vol.1 , pp. 259-271
    • Arany, Z.1    He, H.2    Lin, J.3    Hoyer, K.4    Handschin, C.5    Toka, O.6
  • 6
    • 0036903174 scopus 로고    scopus 로고
    • Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1
    • doi:10.1096/fj.02-0367com. PMID: 12468452
    • Baar, K., Wende, A.R., Jones, T.E., Marison, M., Nolte, L.A., Chen, M., et al. 2002. Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1. FASEB J. 16: 1879-1886. doi:10.1096/fj.02-0367com. PMID: 12468452.
    • (2002) FASEB J. , vol.16 , pp. 1879-1886
    • Baar, K.1    Wende, A.R.2    Jones, T.E.3    Marison, M.4    Nolte, L.A.5    Chen, M.6
  • 7
  • 8
    • 0035985859 scopus 로고    scopus 로고
    • Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy
    • PMID:12070181
    • Booth, F.W., Chakravarthy, M.V., Gordon, S.E., and Spangenburg, E.E. 2002. Waging war on physical inactivity: using modern molecular ammunition against an ancient enemy. J. Appl. Physiol. 93: 3-30. PMID:12070181.
    • (2002) J. Appl. Physiol. , vol.93 , pp. 3-30
    • Booth, F.W.1    Chakravarthy, M.V.2    Gordon, S.E.3    Spangenburg, E.E.4
  • 9
    • 45149108625 scopus 로고    scopus 로고
    • Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake
    • doi:10.1152/ japplphysiol.01231.2007. PMID:18239076
    • Calvo, J.A., Daniels, T.G., Wang, X., Paul, A., Lin, J., Spiegelman, B.M., et al. 2008. Muscle-specific expression of PPARγ coactivator-1α improves exercise performance and increases peak oxygen uptake. J. Appl. Physiol. 104: 1304-1312. doi:10.1152/ japplphysiol.01231.2007. PMID:18239076.
    • (2008) J. Appl. Physiol. , vol.104 , pp. 1304-1312
    • Calvo, J.A.1    Daniels, T.G.2    Wang, X.3    Paul, A.4    Lin, J.5    Spiegelman, B.M.6
  • 10
    • 0032529188 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type
    • doi:10.1101/gad.12.16.2499. PMID:9716403
    • Chin, E.R., Olson, E.N., Richardson, J.A., Yang, Q., Humphries, C., Shelton, J.M., et al. 1998. A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type. Genes Dev. 12: 2499-2509. doi:10.1101/gad.12.16.2499. PMID:9716403.
    • (1998) Genes Dev. , vol.12 , pp. 2499-2509
    • Chin, E.R.1    Olson, E.N.2    Richardson, J.A.3    Yang, Q.4    Humphries, C.5    Shelton, J.M.6
  • 11
    • 0025303456 scopus 로고
    • Effects of endurance exercise on isomyosin patterns in fast-and slow-twitch skeletal muscles
    • PMID:2141832
    • Fitzsimons, D.P., Diffee, G.M., Herrick, R.E., and Baldwin, K.M. 1990. Effects of endurance exercise on isomyosin patterns in fast-and slow-twitch skeletal muscles. J. Appl. Physiol. 68: 1950-1955. PMID:2141832.
    • (1990) J. Appl. Physiol. , vol.68 , pp. 1950-1955
    • Fitzsimons, D.P.1    Diffee, G.M.2    Herrick, R.E.3    Baldwin, K.M.4
  • 12
    • 0000368683 scopus 로고    scopus 로고
    • Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle
    • doi:10.1006/bbrc.2000.3073. PMID:10891387
    • Fujii, N., Hayashi, T., Hirshman, M.F., Smith, J.T., Habinowski, S.A., Kaijser, L., et al. 2000. Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle. Biochem. Biophys. Res. Commun. 273: 1150-1155. doi:10.1006/bbrc.2000.3073. PMID:10891387.
    • (2000) Biochem. Biophys. Res. Commun. , vol.273 , pp. 1150-1155
    • Fujii, N.1    Hayashi, T.2    Hirshman, M.F.3    Smith, J.T.4    Habinowski, S.A.5    Kaijser, L.6
  • 13
    • 33744918508 scopus 로고    scopus 로고
    • Role of calcineurin in exercise-induced mitochondrial biogenesis
    • doi:10.1152/ ajpendo.00633.2005. PMID:16403773
    • Garcia-Roves, P.M., Huss, J., and Holloszy, J.O. 2006. Role of calcineurin in exercise-induced mitochondrial biogenesis. Am. J. Physiol. Endocrinol. Metab. 290: E1172-E1179. doi:10.1152/ ajpendo.00633.2005. PMID:16403773.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.290
    • Garcia-Roves, P.M.1    Huss, J.2    Holloszy, J.O.3
  • 14
    • 0034596268 scopus 로고    scopus 로고
    • cDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats
    • doi:10.1006/ bbrc.2000.3134. PMID:10913342
    • Goto, M., Terada, S., Kato, M., Katoh, M., Yokozeki, T., Tabata, I., and Shimokawa, T. 2000. cDNA Cloning and mRNA analysis of PGC-1 in epitrochlearis muscle in swimming-exercised rats. Biochem. Biophys. Res. Commun. 274: 350-354. doi:10.1006/ bbrc.2000.3134. PMID:10913342.
    • (2000) Biochem. Biophys. Res. Commun. , vol.274 , pp. 350-354
    • Goto, M.1    Terada, S.2    Kato, M.3    Katoh, M.4    Yokozeki, T.5    Tabata, I.6    Shimokawa, T.7
  • 15
    • 0038810035 scopus 로고    scopus 로고
    • An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle
    • doi:10.1073/pnas. 1232352100. PMID:12764228
    • Handschin, C., Rhee, J., Lin, J., Tarr, P.T., and Spiegelman, B.M. 2003. An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle. Proc. Natl. Acad. Sci. U.S.A. 100: 7111-7116. doi:10.1073/pnas. 1232352100. PMID:12764228.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 7111-7116
    • Handschin, C.1    Rhee, J.2    Lin, J.3    Tarr, P.T.4    Spiegelman, B.M.5
  • 16
    • 35648937073 scopus 로고    scopus 로고
    • Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals
    • doi:10.1074/jbc. M704817200. PMID:17702743
    • Handschin, C., Chin, S., Li, P., Liu, F., Maratos-Flier, E., Lebrasseur, N.K., et al. 2007. Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals. J. Biol. Chem. 282: 30014-30021. doi:10.1074/jbc. M704817200. PMID:17702743.
    • (2007) J. Biol. Chem. , vol.282 , pp. 30014-30021
    • Handschin, C.1    Chin, S.2    Li, P.3    Liu, F.4    Maratos-Flier, E.5    Lebrasseur, N.K.6
  • 17
    • 0015865749 scopus 로고
    • The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women and well-trained orienteers
    • doi:10. 1007/BF00588462. PMID:4797912
    • Hoppeler, H., Luthi, P., Claassen, H., Weibel, E.R., and Howald, H. 1973. The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women and well-trained orienteers. Pflugers Arch. 344: 217-232. doi:10. 1007/BF00588462. PMID:4797912.
    • (1973) Pflugers Arch. , vol.344 , pp. 217-232
    • Hoppeler, H.1    Luthi, P.2    Claassen, H.3    Weibel, E.R.4    Howald, H.5
  • 18
    • 0038587678 scopus 로고    scopus 로고
    • PPARγ coactivator-1α expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations
    • PMID:12734114
    • Irrcher, I., Adhihetty, P.J., Sheehan, T., Joseph, A.M., and Hood, D.A. 2003. PPARγ coactivator-1α expression during thyroid hormone-and contractile activity-induced mitochondrial adaptations. Am. J. Physiol. Cell Physiol. 284: C1669-C1677. PMID:12734114.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.284
    • Irrcher, I.1    Adhihetty, P.J.2    Sheehan, T.3    Joseph, A.M.4    Hood, D.A.5
  • 19
    • 0036246979 scopus 로고    scopus 로고
    • Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    • doi:10.1046/j.1532-5415.2002.50216.x. PMID:12028177
    • Janssen, I., Heymsfield, S.B., and Ross, R. 2002. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J. Am. Geriatr. Soc. 50: 889-896. doi:10.1046/j.1532-5415.2002.50216.x. PMID:12028177.
    • (2002) J. Am. Geriatr. Soc. , vol.50 , pp. 889-896
    • Janssen, I.1    Heymsfield, S.B.2    Ross, R.3
  • 20
    • 21744463063 scopus 로고    scopus 로고
    • Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle
    • PMID:15878932
    • Jorgensen, S.B., Wojtaszewski, J.F., Viollet, B., Andreelli, F., Birk, J.B., Hellsten, Y., et al. 2005. Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle. FASEB J. 19: 1146-1148. PMID:15878932.
    • (2005) FASEB J. , vol.19 , pp. 1146-1148
    • Jorgensen, S.B.1    Wojtaszewski, J.F.2    Viollet, B.3    Andreelli, F.4    Birk, J.B.5    Hellsten, Y.6
  • 21
    • 33745221937 scopus 로고    scopus 로고
    • Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise
    • doi:10.1113/ jphysiol.2006.109942. PMID:16690705
    • Jorgensen, S.B., Richter, E.A., and Wojtaszewski, J.F. 2006. Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise. J. Physiol. 574: 17-31. doi:10.1113/ jphysiol.2006.109942. PMID:16690705.
    • (2006) J. Physiol. , vol.574 , pp. 17-31
    • Jorgensen, S.B.1    Richter, E.A.2    Wojtaszewski, J.F.3
  • 22
    • 0035488897 scopus 로고    scopus 로고
    • PGC-1, a versatile coactivator
    • doi:10.1016/S10432760(01)00457-X. PMID:11551810
    • Knutti, D., and Kralli, A. 2001. PGC-1, a versatile coactivator. Trends Endocrinol. Metab. 12: 360-365. doi:10.1016/S10432760(01)00457-X. PMID:11551810.
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 360-365
    • Knutti, D.1    Kralli, A.2
  • 23
    • 38949196761 scopus 로고    scopus 로고
    • PGC-1α is not mandatory for exercise-and training-induced adaptive gene responses in mouse skeletal muscle
    • PMID:18073319
    • Leick, L., Wojtaszewski, J.F., Johansen, S.T., Kiilerich, K., Comes, G., Hellsten, Y., et al. 2008. PGC-1α is not mandatory for exercise-and training-induced adaptive gene responses in mouse skeletal muscle. Am. J. Cell Physiol. 294: E463-E474. PMID:18073319.
    • (2008) Am. J. Cell Physiol. , vol.294
    • Leick, L.1    Wojtaszewski, J.F.2    Johansen, S.T.3    Kiilerich, K.4    Comes, G.5    Hellsten, Y.6
  • 24
    • 21144446106 scopus 로고    scopus 로고
    • PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction abnormal weight control and hepatic steatosis
    • doi:10.1371/journal.pbio.0030101. PMID:15760270
    • Leone, T.C., Lehman, J.J., Finck, B.N., Schaeffer, P.J., Wende, A.R., Boudina, S., et al. 2005. PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol. 3: e101. doi:10.1371/journal.pbio.0030101. PMID:15760270.
    • (2005) PLoS Biol. , vol.3
    • Leone, T.C.1    Lehman, J.J.2    Finck, B.N.3    Schaeffer, P.J.4    Wende, A.R.5    Boudina, S.6
  • 25
    • 0037102256 scopus 로고    scopus 로고
    • Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
    • doi:10. 1038/nature00904. PMID:12181572
    • Lin, J., Wu, H., Tarr, P.T., Zhang, C.Y., Wu, Z., Boss, O., et al. 2002. Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres. Nature, 418: 797-801. doi:10. 1038/nature00904. PMID:12181572.
    • (2002) Nature , vol.418 , pp. 797-801
    • Lin, J.1    Wu, H.2    Tarr, P.T.3    Zhang, C.Y.4    Wu, Z.5    Boss, O.6
  • 26
    • 0034681315 scopus 로고    scopus 로고
    • Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo
    • doi:10.1074/jbc.275.7.4545. PMID:10671477
    • Naya, F.J., Mercer, B., Shelton, J., Richardson, J.A., Williams, R.S., and Olson, E.N. 2000. Stimulation of slow skeletal muscle fiber gene expression by calcineurin in vivo. J. Biol. Chem. 275: 4545-4548. doi:10.1074/jbc.275.7.4545. PMID:10671477.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4545-4548
    • Naya, F.J.1    Mercer, B.2    Shelton, J.3    Richardson, J.A.4    Williams, R.S.5    Olson, E.N.6
  • 27
    • 0037979119 scopus 로고    scopus 로고
    • Altered skeletal muscle phenotypes in calcineurin Aα and Aβ gene-targeted mice
    • doi:10. 1128/MCB.23.12.4331-4343.2003. PMID:12773574
    • Parsons, S.A., Wilkins, B.J., Bueno, O.F., and Molkentin, J.D. 2003. Altered skeletal muscle phenotypes in calcineurin Aα and Aβ gene-targeted mice. Mol. Cell. Biol. 23: 4331-4343. doi:10. 1128/MCB.23.12.4331-4343.2003. PMID:12773574.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4331-4343
    • Parsons, S.A.1    Wilkins, B.J.2    Bueno, O.F.3    Molkentin, J.D.4
  • 28
    • 0037322888 scopus 로고    scopus 로고
    • Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle
    • doi:10.1113/jphysiol. 2002.034850. PMID:12563009
    • Pilegaard, H., Saltin, B., and Neufer, P.D. 2003. Exercise induces transient transcriptional activation of the PGC-1α gene in human skeletal muscle. J. Physiol. 546: 851-858. doi:10.1113/jphysiol. 2002.034850. PMID:12563009.
    • (2003) J. Physiol. , vol.546 , pp. 851-858
    • Pilegaard, H.1    Saltin, B.2    Neufer, P.D.3
  • 29
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • doi:10.1016/S0092-8674(00)81410-5. PMID:9529258
    • Puigserver, P., Wu, Z., Park, C.W., Graves, R., Wright, M., and Spiegelman, B.M. 1998. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell, 92: 829-839. doi:10.1016/S0092-8674(00)81410-5. PMID:9529258.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 30
    • 0033948212 scopus 로고    scopus 로고
    • Sarcopenia and its implications for the elderly
    • PMID:11041074
    • Roubenoff, R. 2000. Sarcopenia and its implications for the elderly. Eur. J. Clin. Nutr. 54(Suppl. 3): S40-S47. PMID:11041074.
    • (2000) Eur. J. Clin. Nutr. , vol.54 , Issue.SUPPL. 3
    • Roubenoff, R.1
  • 31
    • 0035986085 scopus 로고    scopus 로고
    • Invited review:intracellu-lar.signaling in contracting skeletal muscle
    • PMID:12070227
    • Sakamoto, K., and Goodyear, L.J. 2002. Invited review: intracellular signaling in contracting skeletal muscle. J. Appl. Physiol. 93: 369-383. PMID:12070227.
    • (2002) J. Appl. Physiol. , vol.93 , pp. 369-383
    • Sakamoto, K.1    Goodyear, L.J.2
  • 32
    • 0037089040 scopus 로고    scopus 로고
    • Metabolic fitness: physical activity and health
    • PMID: 11989061
    • Saltin, B., and Pilegaard, H. 2002. Metabolic fitness: physical activity and health. Ugeskr. Laeger, 164: 2156-2162. PMID: 11989061.
    • (2002) Ugeskr. Laeger , vol.164 , pp. 2156-2162
    • Saltin, B.1    Pilegaard, H.2
  • 33
    • 33845411854 scopus 로고    scopus 로고
    • Metformin increases the PGC-1α protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo
    • doi:10. 1152/japplphysiol.00255.2006. PMID:16902066
    • Suwa, M., Egashira, T., Nakano, H., Sasaki, H., and Kumagai, S. 2006. Metformin increases the PGC-1α protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo. J. Appl. Physiol. 101: 1685-1692. doi:10. 1152/japplphysiol.00255.2006. PMID:16902066.
    • (2006) J. Appl. Physiol. , vol.101 , pp. 1685-1692
    • Suwa, M.1    Egashira, T.2    Nakano, H.3    Sasaki, H.4    Kumagai, S.5
  • 34
    • 0021484864 scopus 로고
    • Beta-adrenergic blockade and training in human subjects: effects on muscle metabolic capacity
    • PMID:6089581
    • Svedenhag, J., Henriksson, J., and Juhlin-Dannfelt, A. 1984. Beta-adrenergic blockade and training in human subjects: effects on muscle metabolic capacity. Am. J. Physiol. 247: E305-E311. PMID:6089581.
    • (1984) Am. J. Physiol. , vol.247
    • Svedenhag, J.1    Henriksson, J.2    Juhlin-Dannfelt, A.3
  • 35
    • 0036386911 scopus 로고    scopus 로고
    • Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle
    • doi:10.1016/S0006291X(02)00881-1. PMID:12163024
    • Terada, S., Goto, M., Kato, M., Kawanaka, K., Shimokawa, T., and Tabata, I. 2002. Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle. Biochem. Biophys. Res. Commun. 296: 350-354. doi:10.1016/S0006291X(02)00881-1. PMID:12163024.
    • (2002) Biochem. Biophys. Res. Commun. , vol.296 , pp. 350-354
    • Terada, S.1    Goto, M.2    Kato, M.3    Kawanaka, K.4    Shimokawa, T.5    Tabata, I.6
  • 36
    • 0020363397 scopus 로고
    • Increased peripheral insulin sensitivity and muscle mitochondrial enzymes but unchanged blood glucose control in type I diabetics after physical training
    • doi:10.2337/diabetes.31.12. 1044. PMID:6757018
    • Wallberg-Henriksson, H., Gunnarsson, R., Henriksson, J., DeFronzo, R., Felig, P., Ostman, J., and Wahren, J. 1982. Increased peripheral insulin sensitivity and muscle mitochondrial enzymes but unchanged blood glucose control in type I diabetics after physical training. Diabetes, 31: 1044-1050. doi:10.2337/diabetes.31.12. 1044. PMID:6757018.
    • (1982) Diabetes , vol.31 , pp. 1044-1050
    • Wallberg-Henriksson, H.1    Gunnarsson, R.2    Henriksson, J.3    DeFronzo, R.4    Felig, P.5    Ostman, J.6    Wahren, J.7
  • 37
    • 0001171879 scopus 로고    scopus 로고
    • Regulation of gene expression in skeletal muscle by contractile activity
    • Edited by L.B.Rowell and J.T. Shepherd. Oxford University Press New York
    • Williams, R.S., and Neufer, P.D. 1996. Regulation of gene expression in skeletal muscle by contractile activity. In The handbook of physiology. Exercise: regulation and integration of multiple systems. Edited by L.B.Rowell and J.T. Shepherd. Oxford University Press, New York. pp. 1124-1150.
    • (1996) The handbook of physiology. Exercise: regulation and integration of multiple systems , pp. 1124-1150
    • Williams, R.S.1    Neufer, P.D.2
  • 38
    • 0029978799 scopus 로고    scopus 로고
    • Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise
    • PMID:8779952
    • Winder, W.W., and Hardie, D.G. 1996. Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise. Am. J. Physiol. 270: E299-E304. PMID:8779952.
    • (1996) Am. J. Physiol. , vol.270
    • Winder, W.W.1    Hardie, D.G.2
  • 39
    • 0034306362 scopus 로고    scopus 로고
    • Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscle
    • doi:10.1111/j.1469-7793.2000. t01-1-00221.x. PMID:11018120
    • Wojtaszewski, J.F., Nielsen, P., Hansen, B.F., Richter, E.A., and Kiens, B. 2000. Isoform-specific and exercise intensity-dependent activation of 5'-AMP-activated protein kinase in human skeletal muscle. J. Physiol. 528: 221-226. doi:10.1111/j.1469-7793.2000. t01-1-00221.x. PMID:11018120.
    • (2000) J. Physiol. , vol.528 , pp. 221-226
    • Wojtaszewski, J.F.1    Nielsen, P.2    Hansen, B.F.3    Richter, E.A.4    Kiens, B.5
  • 40
    • 33846992686 scopus 로고    scopus 로고
    • Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1α expression
    • doi:10.1074/jbc.M606116200. PMID:17099248
    • Wright, D.C., Han, D.H., Garcia-Roves, P.M., Geiger, P.C., Jones, T.E., and Holloszy, J.O. 2007. Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1α expression. J. Biol. Chem. 282: 194-199. doi:10.1074/jbc.M606116200. PMID:17099248.
    • (2007) J. Biol. Chem. , vol.282 , pp. 194-199
    • Wright, D.C.1    Han, D.H.2    Garcia-Roves, P.M.3    Geiger, P.C.4    Jones, T.E.5    Holloszy, J.O.6
  • 41
    • 0037066459 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
    • doi:10.1126/science.1071163. PMID:11951046
    • Wu, H., Kanatous, S.B., Thurmond, F.A., Gallardo, T., Isotani, E., Bassel-Duby, R., and Williams, R.S. 2002. Regulation of mitochondrial biogenesis in skeletal muscle by CaMK. Science, 296: 349-352. doi:10.1126/science.1071163. PMID:11951046.
    • (2002) Science , vol.296 , pp. 349-352
    • Wu, H.1    Kanatous, S.B.2    Thurmond, F.A.3    Gallardo, T.4    Isotani, E.5    Bassel-Duby, R.6    Williams, R.S.7
  • 42
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • doi:10.1016/S0092-8674(00)80611X. PMID:10412986
    • Wu, Z., Puigserver, P., Andersson, U., Zhang, C., Adelmant, G., Mootha, V., et al. 1999. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell, 98: 115-124. doi:10.1016/S0092-8674(00)80611X. PMID:10412986.
    • (1999) Cell , vol.98 , pp. 115-124
    • Wu, Z.1    Puigserver, P.2    Andersson, U.3    Zhang, C.4    Adelmant, G.5    Mootha, V.6
  • 43
    • 0037058977 scopus 로고    scopus 로고
    • AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
    • doi:10.1073/pnas.252625599. PMID:12444247
    • Zong, H., Ren, J.M., Young, L.H., Pypaert, M., Mu, J., Birnbaum, M.J., and Shulman, G.I. 2002. AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation. Proc. Natl. Acad. Sci. U.S.A. 99: 15983-15987. doi:10.1073/pnas.252625599. PMID:12444247.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 15983-15987
    • Zong, H.1    Ren, J.M.2    Young, L.H.3    Pypaert, M.4    Mu, J.5    Birnbaum, M.J.6    Shulman, G.I.7


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