The ACh-induced contraction in rat aortas is mediated by the Cys Lt 1 receptor via intracellular calcium mobilization in smooth muscle cells

British Journal of Pharmacology

Volumn 138, Issue 4, 2003, Pages 707-715

  Mazzetti, Luca ^a   Franchi Micheli, Sergio ^a   Nistri, Silvia ^a   Quattrone, Silvia ^a   Simone, Ruggero ^a   Ciuffi, Mario ^a   Zilletti, Lucilla ^a   Failli, Paola ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

5 lipoxygenase; Cysteinyl containing leukotriene receptor antagonists; Cysteinyl containing leukotriene receptors; Intracellular calcium; Lipoxygenase metabolites; Rat aortic smooth muscle cells; Rat aortic strips

Indexed keywords

2 (2,6 DIHYDROXYHEXYL) 6 (3 HYDROXY 1,5 UNDECADIENYL)PYRIDINE; 6 (4 CARBOXYPHENYLTHIO) 5 HYDROXY 7,9,11,14 ICOSATETRAENOIC ACID; ACETYLCHOLINE; FURA 2; INDOMETACIN; LEUKOTRIENE B4 RECEPTOR ANTAGONIST; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE RECEPTOR; MONTELUKAST; PEPTIDOLEUKOTRIENE; PHENYLEPHRINE; PROTEIN SUBUNIT; VERLUKAST;

ANIMAL TISSUE; AORTA CONSTRICTION; AORTA MEDIA; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; HEART CONTRACTION; IC 50; MALE; MUSCLE TONE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ACETYLCHOLINE; ANIMALS; AORTA, THORACIC; CALCIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; INTRACELLULAR FLUID; LEUKOTRIENE ANTAGONISTS; LEUKOTRIENE D4; MALE; MEMBRANE PROTEINS; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, WISTAR; RECEPTORS, LEUKOTRIENE; VASOCONSTRICTION;

EID: 0037294509     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705087     Document Type: Article

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