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Volumn 13, Issue 2 II, 2007, Pages

Open discussion

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; GROWTH FACTOR; SORAFENIB; SUNITINIB; VASCULOTROPIN RECEPTOR; INTERFERON; PLACEBO; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RAF PROTEIN; TEMSIROLIMUS;

EID: 33846873429     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-2063     Document Type: Note
Times cited : (57)

References (28)
  • 1
    • 0026572345 scopus 로고
    • The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor
    • De Vries C, Escobedo JA, Ueno H, et al. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992;255:989-91.
    • (1992) Science , vol.255 , pp. 989-991
    • De Vries, C.1    Escobedo, J.A.2    Ueno, H.3
  • 2
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong GH, Rossant J, Gertsenstein M, et al. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 1995;376:66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3
  • 3
    • 0034665166 scopus 로고    scopus 로고
    • Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice
    • Brekken RA, Overholser JP, Stastny VA, et al. Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice. Cancer Res 2000;18:5117-24.
    • (2000) Cancer Res , vol.18 , pp. 5117-5124
    • Brekken, R.A.1    Overholser, J.P.2    Stastny, V.A.3
  • 4
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka S, Minowa O, Kuno J, et al. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci U S A 1998;95:9349-54.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3
  • 5
    • 0036144374 scopus 로고    scopus 로고
    • Lymphatic endothelium: A new frontier of metastasis research
    • Karkkainen MJ, Makinen T, Alitalo K. Lymphatic endothelium: a new frontier of metastasis research. Nat Cell Biol 2000;4:E2-5.
    • (2000) Nat Cell Biol , vol.4
    • Karkkainen, M.J.1    Makinen, T.2    Alitalo, K.3
  • 6
    • 0035266283 scopus 로고    scopus 로고
    • Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
    • Karpanen T, Egeblad M, Karkkainen MJ, et al. Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 2001;61:1786-90.
    • (2001) Cancer Res , vol.61 , pp. 1786-1790
    • Karpanen, T.1    Egeblad, M.2    Karkkainen, M.J.3
  • 7
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 8
    • 0025998409 scopus 로고
    • Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression
    • Holmgren L, Glaser A, Pfeifer-Ohlsson S, et al. Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression. Development 1991;113:749-54.
    • (1991) Development , vol.113 , pp. 749-754
    • Holmgren, L.1    Glaser, A.2    Pfeifer-Ohlsson, S.3
  • 9
    • 0032973230 scopus 로고    scopus 로고
    • Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact
    • Hirschi KK, Rohovsky SA, Beck LH, et al. Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. Circ Res 1999;84:298-305.
    • (1999) Circ Res , vol.84 , pp. 298-305
    • Hirschi, K.K.1    Rohovsky, S.A.2    Beck, L.H.3
  • 10
    • 0034888832 scopus 로고    scopus 로고
    • Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury
    • Yu JC, Lokker NA, Hollenbach S, et al. Efficacy of the novel selective platelet-derived growth factor receptor antagonist CT52923 on cellular proliferation, migration, and suppression of neointima following vascular injury. J Pharmacol Exp Ther 2001;298:1172-78.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1172-1178
    • Yu, J.C.1    Lokker, N.A.2    Hollenbach, S.3
  • 11
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin LE, Hemo I, Keshet E. A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 1998;125:1591-8.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.E.1    Hemo, I.2    Keshet, E.3
  • 12
    • 0032952010 scopus 로고    scopus 로고
    • Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
    • Benjamin LE, Golijanin D, Itin A, et al. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J Clin Invest 1999;103:159-65.
    • (1999) J Clin Invest , vol.103 , pp. 159-165
    • Benjamin, L.E.1    Golijanin, D.2    Itin, A.3
  • 13
    • 0036251213 scopus 로고    scopus 로고
    • Platelet-derived growth factor-BB: A survival factor for the retinal microvasculature during periods of metabolic compromise
    • Kodama T, Oku H, Kawamura H, et al. Platelet-derived growth factor-BB: a survival factor for the retinal microvasculature during periods of metabolic compromise. Curr Eye Res 2001;23:93-7.
    • (2001) Curr Eye Res , vol.23 , pp. 93-97
    • Kodama, T.1    Oku, H.2    Kawamura, H.3
  • 14
    • 0033772236 scopus 로고    scopus 로고
    • Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice
    • Blaskovich MA, Lin Q, Delarue FL, et al. Design of GFB-111, a platelet-derived growth factor binding molecule with antiangiogenic and anticancer activity against human tumors in mice. Nat Biotechnol 2000;18:1065-70.
    • (2000) Nat Biotechnol , vol.18 , pp. 1065-1070
    • Blaskovich, M.A.1    Lin, Q.2    Delarue, F.L.3
  • 15
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • Bergers G, Song S, Meyer-Morse N, et al. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003;111:1287-95.
    • (2003) J Clin Invest , vol.111 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3
  • 16
    • 0033118228 scopus 로고    scopus 로고
    • VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
    • Takahashi T, Ueno H, Shibuya M. VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells. Oncogene 1999;18:2221-30.
    • (1999) Oncogene , vol.18 , pp. 2221-2230
    • Takahashi, T.1    Ueno, H.2    Shibuya, M.3
  • 17
    • 0033573895 scopus 로고    scopus 로고
    • VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases
    • Doanes AM, Hegland DD, Sethi R, et al. VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. Biochem Biophys Res Commun 1999;255:545-8.
    • (1999) Biochem Biophys Res Commun , vol.255 , pp. 545-548
    • Doanes, A.M.1    Hegland, D.D.2    Sethi, R.3
  • 18
    • 0037189380 scopus 로고    scopus 로고
    • Tumor regression by targeted gene delivery to the neovasculature
    • Hood JD, Bednarski M, Frausto R, et al. Tumor regression by targeted gene delivery to the neovasculature. Science 2002;296:2404-7.
    • (2002) Science , vol.296 , pp. 2404-2407
    • Hood, J.D.1    Bednarski, M.2    Frausto, R.3
  • 19
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109.
    • (2004) Cancer Res , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1    Carter, C.2    Tang, L.3
  • 20
    • 20044382799 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors
    • Strumberg D, Richly H, Hilger RA, et al. Phase I clinical and pharmacokinetic study of the novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors. J Clin Oncol 2005;23:965-72.
    • (2005) J Clin Oncol , vol.23 , pp. 965-972
    • Strumberg, D.1    Richly, H.2    Hilger, R.A.3
  • 21
    • 4644276593 scopus 로고    scopus 로고
    • Preliminary antitumor activity of BAY 43-9006 in metastatic renal cell carcinoma and other advanced refractory solid tumors in a phase II randomized discontinuation trial (RDT)
    • Ratain M, Flaherty KT, Stadler WM, et al. Preliminary antitumor activity of BAY 43-9006 in metastatic renal cell carcinoma and other advanced refractory solid tumors in a phase II randomized discontinuation trial (RDT). J Clin Oncol 2004;22:4501.
    • (2004) J Clin Oncol , vol.22 , pp. 4501
    • Ratain, M.1    Flaherty, K.T.2    Stadler, W.M.3
  • 22
    • 23844558595 scopus 로고    scopus 로고
    • Randomized phase III trial of the Raf kinase and VEGFR inhibitor sorafenib (BAY 43-9006) in patients with advanced renal cell carcinoma (RCC) [abstract LBA4510]
    • 380s
    • Escudler B, Szczylik C, Eisen T, et al. Randomized phase III trial of the Raf kinase and VEGFR inhibitor sorafenib (BAY 43-9006) in patients with advanced renal cell carcinoma (RCC) [abstract LBA4510]. Proc Am Soc Clin Oncol 2005;23:380s.
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • Escudler, B.1    Szczylik, C.2    Eisen, T.3
  • 23
    • 33646272299 scopus 로고    scopus 로고
    • Pharmacodynamic study of BAY 43-9006 in patients with metastatic renal cell carcinoma
    • 193s
    • O'Dwyer PJ, Rosen M, Gallagher M, et al. Pharmacodynamic study of BAY 43-9006 in patients with metastatic renal cell carcinoma. Proc Am Soc Clin Oncol 2005;23:193s.
    • (2005) Proc Am Soc Clin Oncol , vol.23
    • O'Dwyer, P.J.1    Rosen, M.2    Gallagher, M.3
  • 24
    • 33645449812 scopus 로고    scopus 로고
    • Mechanisms of hypertension associated with BAY 43-9006
    • Veronese ML, Mosenkis A, Flaherty KT, et al. Mechanisms of hypertension associated with BAY 43-9006. J Clin Oncol 2006;24:1363-9.
    • (2006) J Clin Oncol , vol.24 , pp. 1363-1369
    • Veronese, M.L.1    Mosenkis, A.2    Flaherty, K.T.3
  • 25
    • 0037235049 scopus 로고    scopus 로고
    • VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide
    • Breslin JW, Pappas PJ, Cerveira JJ, et al. VEGF increases endothelial permeability by separate signaling pathways involving ERK-1/2 and nitric oxide. Am J Physiol Heart Circ Physiol 2003;284:H92-100.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Breslin, J.W.1    Pappas, P.J.2    Cerveira, J.J.3
  • 26
    • 0035253739 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer
    • Gordon MS, Margolin K, Talpaz M, et al. Phase I safety and pharmacokinetic study of recombinant human anti-vascular endothelial growth factor in patients with advanced cancer. J Clin Oncol 2001;19:843-50.
    • (2001) J Clin Oncol , vol.19 , pp. 843-850
    • Gordon, M.S.1    Margolin, K.2    Talpaz, M.3
  • 27
    • 0036789574 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin
    • Hudson CC, Liu M, Chiang GG, et al. Regulation of hypoxia-inducible factor 1α expression and function by the mammalian target of rapamycin. Mol Cell Biol 2002;22:7004-14.
    • (2002) Mol Cell Biol , vol.22 , pp. 7004-7014
    • Hudson, C.C.1    Liu, M.2    Chiang, G.G.3
  • 28
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 1999;399:271-5.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.