Chemopreventive potential of Epoxy clerodane diterpene from Tinospora cordifolia against diethylnitrosamine-induced hepatocellular carcinoma

Investigational New Drugs

Volumn 27, Issue 4, 2009, Pages 347-355

  Dhanasekaran, Muniyappan ^a   Baskar, Arul Albert ^a   Ignacimuthu, Savarimuthu ^a   Agastian, Paul ^a   Duraipandiyan, Veeramuthu ^a  

^a LOYOLA COLLEGE   (India)

Author keywords

(5R,10R) 4R,8R Dihydroxy 2S,3R:15,16 diepoxycleroda 13(16),17,12S:18, 1S dilactone; Diethylnitrosamine; Epoxy clerodane diterpene; Hepatocellular carcinoma; Tinospora cordifolia

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CATALASE; CLERODANE DERIVATIVE; DIETHYLNITROSAMINE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; LACTATE DEHYDROGENASE; SUPEROXIDE DISMUTASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; HISTOPATHOLOGY; LIVER; LIVER CELL; LIVER CELL CARCINOMA; MALE; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; RAT; TINOSPORA CORDIFOLIA; WISTAR RAT;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CARCINOMA, HEPATOCELLULAR; DIETHYLNITROSAMINE; DITERPENES, CLERODANE; DRUG SCREENING ASSAYS, ANTITUMOR; LIVER NEOPLASMS, EXPERIMENTAL; MALE; RATS; RATS, WISTAR; TINOSPORA;

EID: 67651171647     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10637-008-9181-9     Document Type: Article

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