-
1
-
-
0035962631
-
DNA methylation, methyltransferases, and cancer
-
Robertson KD. DNA methylation, methyltransferases, and cancer. Oncogene 2001; 20: 3139-3155
-
(2001)
Oncogene
, vol.20
, pp. 3139-3155
-
-
Robertson, K.D.1
-
2
-
-
34347233479
-
DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2
-
McGarvey KM, Greene E, Fahrner JA, Jenuwein T, Baylin SB. DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2. Cancer Res 2007; 67: 5097-5102
-
(2007)
Cancer Res
, vol.67
, pp. 5097-5102
-
-
McGarvey, K.M.1
Greene, E.2
Fahrner, J.A.3
Jenuwein, T.4
Baylin, S.B.5
-
3
-
-
0033919595
-
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 2000; 25: 338-342
-
(2000)
Nat Genet
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
4
-
-
0033753779
-
The DNA methyltransferases of mammals
-
Bestor TH. The DNA methyltransferases of mammals. Hum Mol Genet 2000; 9: 2395-2402
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2395-2402
-
-
Bestor, T.H.1
-
5
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
-
Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet 1998; 19: 219-220
-
(1998)
Nat Genet
, vol.19
, pp. 219-220
-
-
Okano, M.1
Xie, S.2
Li, E.3
-
6
-
-
40949161396
-
Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma
-
Nishida N, Nagasaka T, Nishimura T, Ikai I, Boland CR, Goel A. Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology 2008; 47: 908-918
-
(2008)
Hepatology
, vol.47
, pp. 908-918
-
-
Nishida, N.1
Nagasaka, T.2
Nishimura, T.3
Ikai, I.4
Boland, C.R.5
Goel, A.6
-
7
-
-
0037400909
-
Decrease of DNA methyltransferase 1 expression relative to cell proliferation in transitional cell carcinoma
-
Kimura F, Seifert HH, Florl AR, Santourlidis S, Steinhoff C, Swiatkowski S, Mahotka C, Gerharz CD, Schulz WA. Decrease of DNA methyltransferase 1 expression relative to cell proliferation in transitional cell carcinoma. Int J Cancer 2003; 104: 568-578
-
(2003)
Int J Cancer
, vol.104
, pp. 568-578
-
-
Kimura, F.1
Seifert, H.H.2
Florl, A.R.3
Santourlidis, S.4
Steinhoff, C.5
Swiatkowski, S.6
Mahotka, C.7
Gerharz, C.D.8
Schulz, W.A.9
-
8
-
-
0031442751
-
Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis
-
Sun L, Hui AM, Kanai Y, Sakamoto M, Hirohashi S. Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis. Jpn J Cancer Res 1997; 88: 1165-1170
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 1165-1170
-
-
Sun, L.1
Hui, A.M.2
Kanai, Y.3
Sakamoto, M.4
Hirohashi, S.5
-
9
-
-
0035127794
-
Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis
-
Saito Y, Kanai Y, Sakamoto M, Saito H, Ishii H, Hirohashi S. Expression of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and DNA methylation status on CpG islands and pericentromeric satellite regions during human hepatocarcinogenesis. Hepatology 2001; 33: 561-568
-
(2001)
Hepatology
, vol.33
, pp. 561-568
-
-
Saito, Y.1
Kanai, Y.2
Sakamoto, M.3
Saito, H.4
Ishii, H.5
Hirohashi, S.6
-
10
-
-
0037255729
-
Expression of DNA methyltransferases in multistep hepatocarcinogenesis
-
Choi MS, Shim YH, Hwa JY, Lee SK, Ro JY, Kim JS, Yu E. Expression of DNA methyltransferases in multistep hepatocarcinogenesis. Hum Pathol 2003; 34: 11-17
-
(2003)
Hum Pathol
, vol.34
, pp. 11-17
-
-
Choi, M.S.1
Shim, Y.H.2
Hwa, J.Y.3
Lee, S.K.4
Ro, J.Y.5
Kim, J.S.6
Yu, E.7
-
11
-
-
0035863455
-
DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers
-
Kanai Y, Ushijima S, Kondo Y, Nakanishi Y, Hirohashi S. DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. Int J Cancer 2001; 91: 205-212
-
(2001)
Int J Cancer
, vol.91
, pp. 205-212
-
-
Kanai, Y.1
Ushijima, S.2
Kondo, Y.3
Nakanishi, Y.4
Hirohashi, S.5
-
12
-
-
0035839057
-
The role of DNA methylation in mammalian epigenetics
-
Jones PA, Takai D. The role of DNA methylation in mammalian epigenetics. Science 2001; 293: 1068-1070
-
(2001)
Science
, vol.293
, pp. 1068-1070
-
-
Jones, P.A.1
Takai, D.2
-
13
-
-
0034176798
-
DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
-
Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000; 16: 168-174
-
(2000)
Trends Genet
, vol.16
, pp. 168-174
-
-
Baylin, S.B.1
Herman, J.G.2
-
14
-
-
1542319832
-
Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers
-
Etoh T, Kanai Y, Ushijima S, Nakagawa T, Nakanishi Y, Sasako M, Kitano S, Hirohashi S. Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am J Pathol 2004; 164: 689-699
-
(2004)
Am J Pathol
, vol.164
, pp. 689-699
-
-
Etoh, T.1
Kanai, Y.2
Ushijima, S.3
Nakagawa, T.4
Nakanishi, Y.5
Sasako, M.6
Kitano, S.7
Hirohashi, S.8
-
15
-
-
0027051417
-
Clonal growth of hepatitis B virus-integrated hepatocytes in cirrhotic liver nodules
-
Yasui H, Hino O, Ohtake K, Machinami R, Kitagawa T. Clonal growth of hepatitis B virus-integrated hepatocytes in cirrhotic liver nodules. Cancer Res 1992; 52: 6810-6814
-
(1992)
Cancer Res
, vol.52
, pp. 6810-6814
-
-
Yasui, H.1
Hino, O.2
Ohtake, K.3
Machinami, R.4
Kitagawa, T.5
-
16
-
-
37349036468
-
DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721
-
Fan H, Zhao Z, Quan Y, Xu J, Zhang J, Xie W. DNA methyltransferase 1 knockdown induces silenced CDH1 gene reexpression by demethylation of methylated CpG in hepatocellular carcinoma cell line SMMC-7721. Eur J Gastroenterol Hepatol 2007; 19: 952-961
-
(2007)
Eur J Gastroenterol Hepatol
, vol.19
, pp. 952-961
-
-
Fan, H.1
Zhao, Z.2
Quan, Y.3
Xu, J.4
Zhang, J.5
Xie, W.6
-
17
-
-
0037130479
-
The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines
-
Sato M, Horio Y, Sekido Y, Minna JD, Shimokata K, Hasegawa Y. The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines. Oncogene 2002; 21: 4822-4829
-
(2002)
Oncogene
, vol.21
, pp. 4822-4829
-
-
Sato, M.1
Horio, Y.2
Sekido, Y.3
Minna, J.D.4
Shimokata, K.5
Hasegawa, Y.6
-
18
-
-
0024203946
-
Clonal origin of atypical adenomatous hyperplasia of the liver and clonal identity with hepatocellular carcinoma
-
Tsuda H, Hirohashi S, Shimosato Y, Terada M, Hasegawa H. Clonal origin of atypical adenomatous hyperplasia of the liver and clonal identity with hepatocellular carcinoma. Gastroenterology 1988; 95: 1664-1666
-
(1988)
Gastroenterology
, vol.95
, pp. 1664-1666
-
-
Tsuda, H.1
Hirohashi, S.2
Shimosato, Y.3
Terada, M.4
Hasegawa, H.5
-
19
-
-
44949106316
-
Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis
-
Liao X, Siu MK, Chan KY, Wong ES, Ngan HY, Chan QK, Li AS, Khoo US, Cheung AN. Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. Int J Cancer 2008; 123: 296-302
-
(2008)
Int J Cancer
, vol.123
, pp. 296-302
-
-
Liao, X.1
Siu, M.K.2
Chan, K.Y.3
Wong, E.S.4
Ngan, H.Y.5
Chan, Q.K.6
Li, A.S.7
Khoo, U.S.8
Cheung, A.N.9
-
20
-
-
33644642358
-
DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma
-
Park HJ, Yu E, Shim YH. DNA methyltransferase expression and DNA hypermethylation in human hepatocellular carcinoma. Cancer Lett 2006; 233: 271-278
-
(2006)
Cancer Lett
, vol.233
, pp. 271-278
-
-
Park, H.J.1
Yu, E.2
Shim, Y.H.3
-
21
-
-
33747830764
-
Hepatocellular carcinoma pathogenesis: From genes to environment
-
Farazi PA, DePinho RA. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat Rev Cancer 2006; 6: 674-687
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 674-687
-
-
Farazi, P.A.1
DePinho, R.A.2
-
22
-
-
33745627069
-
DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas
-
Peng DF, Kanai Y, Sawada M, Ushijima S, Hiraoka N, Kitazawa S, Hirohashi S. DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas. Carcinogenesis 2006; 27: 1160-1168
-
(2006)
Carcinogenesis
, vol.27
, pp. 1160-1168
-
-
Peng, D.F.1
Kanai, Y.2
Sawada, M.3
Ushijima, S.4
Hiraoka, N.5
Kitazawa, S.6
Hirohashi, S.7
-
23
-
-
24044493602
-
Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer
-
Agoston AT, Argani P, Yegnasubramanian S, De Marzo AM, Ansari-Lari MA, Hicks JL, Davidson NE, Nelson WG. Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer. J Biol Chem 2005; 280: 18302-18310
-
(2005)
J Biol Chem
, vol.280
, pp. 18302-18310
-
-
Agoston, A.T.1
Argani, P.2
Yegnasubramanian, S.3
De Marzo, A.M.4
Ansari-Lari, M.A.5
Hicks, J.L.6
Davidson, N.E.7
Nelson, W.G.8
-
24
-
-
0242523715
-
Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder
-
Nakagawa T, Kanai Y, Saito Y, Kitamura T, Kakizoe T, Hirohashi S. Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder. J Urol 2003; 170: 2463-2466
-
(2003)
J Urol
, vol.170
, pp. 2463-2466
-
-
Nakagawa, T.1
Kanai, Y.2
Saito, Y.3
Kitamura, T.4
Kakizoe, T.5
Hirohashi, S.6
-
25
-
-
24344465856
-
Epigenetic changes in virus-associated human cancers
-
Li HP, Leu YW, Chang YS. Epigenetic changes in virus-associated human cancers. Cell Res 2005; 15: 262-271
-
(2005)
Cell Res
, vol.15
, pp. 262-271
-
-
Li, H.P.1
Leu, Y.W.2
Chang, Y.S.3
-
26
-
-
34247190634
-
Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein
-
Park IY, Sohn BH, Yu E, Suh DJ, Chung YH, Lee JH, Surzycki SJ, Lee YI. Aberrant epigenetic modifications in hepatocarcinogenesis induced by hepatitis B virus X protein. Gastroenterology 2007; 132: 1476-1494
-
(2007)
Gastroenterology
, vol.132
, pp. 1476-1494
-
-
Park, I.Y.1
Sohn, B.H.2
Yu, E.3
Suh, D.J.4
Chung, Y.H.5
Lee, J.H.6
Surzycki, S.J.7
Lee, Y.I.8
-
27
-
-
0035545996
-
Mammalian G1- and S-phase checkpoints in response to DNA damage
-
Bartek J, Lukas J. Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 2001; 13: 738-747
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 738-747
-
-
Bartek, J.1
Lukas, J.2
-
28
-
-
33749868662
-
Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma
-
Zhang H, Ozaki I, Mizuta T, Hamajima H, Yasutake T, Eguchi Y, Ideguchi H, Yamamoto K, Matsuhashi S. Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma. Oncogene 2006; 25: 6101-6112
-
(2006)
Oncogene
, vol.25
, pp. 6101-6112
-
-
Zhang, H.1
Ozaki, I.2
Mizuta, T.3
Hamajima, H.4
Yasutake, T.5
Eguchi, Y.6
Ideguchi, H.7
Yamamoto, K.8
Matsuhashi, S.9
-
29
-
-
7944225548
-
Induction of PDCD4 tumor suppressor gene expression by RAR agonists, antiestrogen and HER-2/neu antagonist in breast cancer cells. Evidence for a role in apoptosis
-
Afonja O, Juste D, Das S, Matsuhashi S, Samuels HH. Induction of PDCD4 tumor suppressor gene expression by RAR agonists, antiestrogen and HER-2/neu antagonist in breast cancer cells. Evidence for a role in apoptosis. Oncogene 2004; 23: 8135-8145
-
(2004)
Oncogene
, vol.23
, pp. 8135-8145
-
-
Afonja, O.1
Juste, D.2
Das, S.3
Matsuhashi, S.4
Samuels, H.H.5
-
30
-
-
49649102818
-
siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression
-
Bitomsky N, Wethkamp N, Marikkannu R, Klempnauer KH. siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression. Oncogene 2008; 27: 4820-4829
-
(2008)
Oncogene
, vol.27
, pp. 4820-4829
-
-
Bitomsky, N.1
Wethkamp, N.2
Marikkannu, R.3
Klempnauer, K.H.4
|