Envelope-type lipid nanoparticles incorporating a short PEG-lipid conjugate for improved control of intracellular trafficking and transgene transcription

Biomaterials

Volumn 30, Issue 27, 2009, Pages 4806-4814

  Masuda, Tomoya ^a,c   Akita, Hidetaka ^a,c   Niikura, Kenichi ^a   Nishio, Takashi ^a   Ukawa, Masami ^a,c   Enoto, Kaoru ^a,c   Danev, Radostin ^b   Nagayama, Kuniaki ^b   Ijiro, Kuniharu ^a   Harashima, Hideyoshi ^a,c  

^a HOKKAIDO UNIVERSITY   (Japan)

^b OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Envelope type lipid nanoparticle; Gene delivery; Intracellular trafficking; Non viral vector; Short PEG

Indexed keywords

ENVELOPE-TYPE LIPID NANOPARTICLE; GENE DELIVERY; INTRACELLULAR TRAFFICKING; NON-VIRAL VECTOR; SHORT PEG;

ETHYLENE; ETHYLENE GLYCOL; GENE TRANSFER; LIPOSOMES; NANOPARTICLES; NUCLEIC ACIDS; PHOSPHOLIPIDS; THERMOELECTRIC EQUIPMENT; TRANSCRIPTION;

POLYETHYLENE GLYCOLS;

CHOLESTEROL; GLYCOL; LIPID NANOPARTICLE; LIPOSOME; MACROGOL; NANOPARTICLE; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CHEMICAL COMPOSITION; CONTROLLED STUDY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; LIPOSOMAL GENE DELIVERY SYSTEM; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL;

ARGININE; BIOLOGICAL TRANSPORT; CELL NUCLEUS; DNA; HELA CELLS; HUMANS; INTRACELLULAR SPACE; LIPIDS; LUCIFERASES; MICROSCOPY, CONFOCAL; MOLECULAR WEIGHT; NANOPARTICLES; PLASMIDS; POLYETHYLENE GLYCOLS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSGENES;

TETRA;

EID: 67651158802     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.05.036     Document Type: Article

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