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Volumn 14, Issue 6, 2009, Pages 662-667

Novel temperature activation cell-based assay on thermo-TRP ion channels

Author keywords

Cell based assay; Dorsal root ganglion cells; Temperature activation; Thermo TRP

Indexed keywords

ANALGESIC AGENT; CALCIUM; CAPSAZEPINE; ION CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2;

EID: 67651036578     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057109336595     Document Type: Article
Times cited : (11)

References (15)
  • 2
    • 34248138496 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
    • Szallasi A., Cortright DN, Blum CA, Eid SR: The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 2007 ; 6: 357-372.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 357-372
    • Szallasi, A.1    Cortright, D.N.2    Blum, C.A.3    Eid, S.R.4
  • 3
    • 34047118624 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation
    • Gavva NR, Bannon AW, Surapaneni S., Hovland DN Jr, Lehto SG, Gore A., et al. The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation. J Neurosci 2007 ; 27: 3366-3374.
    • (2007) J Neurosci , vol.27 , pp. 3366-3374
    • Gavva, N.R.1    Bannon, A.W.2    Surapaneni, S.3    Hovland Jr., D.N.4    Lehto, S.G.5    Gore, A.6
  • 4
    • 39449102203 scopus 로고    scopus 로고
    • Peripheral TRPV1 receptors as targets for drug development: New molecules and mechanisms
    • Gunthorpe MJ, Szallasi A.: Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms. Curr Pharm Des 2008 ; 14: 32-41.
    • (2008) Curr Pharm des , vol.14 , pp. 32-41
    • Gunthorpe, M.J.1    Szallasi, A.2
  • 6
    • 4043077669 scopus 로고    scopus 로고
    • The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
    • Voets T., Droogmans G., Wissenbach U., Janssens A., Flockerzi V., Nilius B.: The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels. Nature 2004 ; 430: 748-754.
    • (2004) Nature , vol.430 , pp. 748-754
    • Voets, T.1    Droogmans, G.2    Wissenbach, U.3    Janssens, A.4    Flockerzi, V.5    Nilius, B.6
  • 7
    • 0028021842 scopus 로고
    • The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin
    • Walpole CS, Bevan S., Bovermann G., Boelsterli JJ, Breckenridge R., Davies JW, et al. The discovery of capsazepine, the first competitive antagonist of the sensory neuron excitants capsaicin and resiniferatoxin. J Med Chem 1994 ; 37: 1942-1954.
    • (1994) J Med Chem , vol.37 , pp. 1942-1954
    • Walpole, C.S.1    Bevan, S.2    Bovermann, G.3    Boelsterli, J.J.4    Breckenridge, R.5    Davies, J.W.6
  • 8
    • 33846881317 scopus 로고    scopus 로고
    • Utility of a large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists
    • Chen J., Lake MR, Sabet RS, Niforatos W., Pratt SD, Cassar SC, et al. Utility of a large-scale transiently transfected cells for cell-based high-throughput screens to identify transient receptor potential channel A1 (TRPA1) antagonists. J Biomol Screen 2007 ; 12: 61-69.
    • (2007) J Biomol Screen , vol.12 , pp. 61-69
    • Chen, J.1    Lake, M.R.2    Sabet, R.S.3    Niforatos, W.4    Pratt, S.D.5    Cassar, S.C.6
  • 11
    • 34547953765 scopus 로고    scopus 로고
    • ThermoTRP channels as modular proteins with allosteric gating
    • Latorre R., Brauchi S., Orta G., Zaelzer C., Vargas G.: ThermoTRP channels as modular proteins with allosteric gating. Cell Calcium 2007 ; 42: 427-438.
    • (2007) Cell Calcium , vol.42 , pp. 427-438
    • Latorre, R.1    Brauchi, S.2    Orta, G.3    Zaelzer, C.4    Vargas, G.5
  • 12
    • 50249186498 scopus 로고    scopus 로고
    • Pore region of TRPV3 ion channel is specifically required for heat activation
    • Grandl J., Hu H., Bandell M., Bursulaya B., Schmidt M., Petrus M., et al. Pore region of TRPV3 ion channel is specifically required for heat activation. Nat Neurosci 2008 ; 11: 1007-1013.
    • (2008) Nat Neurosci , vol.11 , pp. 1007-1013
    • Grandl, J.1    Hu, H.2    Bandell, M.3    Bursulaya, B.4    Schmidt, M.5    Petrus, M.6
  • 14
    • 0035793024 scopus 로고    scopus 로고
    • Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1
    • Savidge JR, Ranasinghe SP, Rang HP: Comparison of intracellular calcium signals evoked by heat and capsaicin in cultured rat dorsal root ganglion neurons and in a cell line expressing the rat vanilloid receptor, VR1. Neuroscience 2001 ; 102: 177-184.
    • (2001) Neuroscience , vol.102 , pp. 177-184
    • Savidge, J.R.1    Ranasinghe, S.P.2    Rang, H.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.