How to find simple and accurate rules for viral protease cleavage specificities

BMC Bioinformatics

Volumn 10, Issue , 2009, Pages

  Rögnvaldsson, Thorsteinn ^a,b   Etchells, Terence A ^c   You, Liwen ^a,d   Garwicz, Daniel ^e,f   Jarman, Ian ^c   Lisboa, Paulo J G ^c  

^a HALMSTAD UNIVERSITY   (Sweden)

^b ÖREBRO UNIVERSITY   (Sweden)

^c LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^d LUND UNIVERSITY   (Sweden)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^f UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CLEAVAGE SPECIFICITY; CONSENSUS SEQUENCE; HUMAN IMMUNODEFICIENCY VIRUS TYPE-1; ORTHOGONAL SEARCH-BASED RULE EXTRACTIONS; PREDICTION PERFORMANCE; RULE EXTRACTION METHOD; SPECTRAL CLUSTERING; SUBSTRATE SPECIFICITY;

EXTRACTION; VIRUSES;

DISEASES;

SERINE PROTEINASE; NS3 PROTEIN, HEPATITIS C VIRUS; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1; PEPTIDE HYDROLASE; PROTEINASE; PROTEINASE INHIBITOR; VIRUS PROTEIN;

ACCURACY; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DATA ANALYSIS; DRUG TARGETING; ENZYME DEGRADATION; ENZYME SPECIFICITY; GENOTYPE; HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; METHODOLOGY; NUCLEOTIDE SEQUENCE; PREDICTION; SENSITIVITY AND SPECIFICITY; VIRAL GENETICS; AMINO ACID SEQUENCE; CHEMISTRY; CLUSTER ANALYSIS; COMPUTER SIMULATION; ENZYME ACTIVE SITE; GENETICS; HUMAN; METABOLISM; PROTEIN DATABASE; PROTEOMICS; REPRODUCIBILITY; ROC CURVE; STATISTICAL ANALYSIS;

HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CLUSTER ANALYSIS; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DATABASES, PROTEIN; HIV PROTEASE; HUMANS; PEPTIDE HYDROLASES; PROTEASE INHIBITORS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; ROC CURVE; SERINE ENDOPEPTIDASES; VIRAL NONSTRUCTURAL PROTEINS; VIRAL PROTEINS;

EID: 67650914275     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-10-149     Document Type: Article

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