Selenium variation induced oxidative stress regulates p53 dependent germ cell apoptosis: Plausible involvement of HSP70-2

European Journal of Nutrition

Volumn 48, Issue 4, 2009, Pages 221-227

  Kaushal, Naveen ^a   Bansal, M P ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Apoptosis, apoptotic index; HSP70 2; Oxidative stress; P53; Selenium

Indexed keywords

GLUTATHIONE; GLUTATHIONE DISULFIDE; HEAT SHOCK PROTEIN 70; MESSENGER RNA; PROTEIN P53; SELENIUM; SODIUM SELENITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA DAMAGE; DNA FRAGMENTATION; GERM CELL; MALE; MOUSE; NICK END LABELING; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN EXPRESSION; SELENIUM DEFICIENCY; SPERMATOGENESIS; TESTIS; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; DNA DAMAGE; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GLUTATHIONE PEROXIDASE; HSP70 HEAT-SHOCK PROTEINS; IN SITU NICK-END LABELING; INFERTILITY, MALE; MALE; MICE; MICE, INBRED BALB C; OXIDATION-REDUCTION; OXIDATIVE STRESS; RANDOM ALLOCATION; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SELENIUM; SPERMATOGENESIS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MUS;

EID: 67650869566     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-009-0005-2     Document Type: Article

References (35)

1. E Almon N Goldfinger A Kapon D Schwartz AJ Levine V Rotter 1993 Testicular tissue-specific expression of the p53 suppressor gene Dev Biol 156 107 116
2. EI Azzam SM De Toledo MJ Pykett H Nagasawa JB Little 1997 CDC2 is down-regulated by ionizing radiation in a p53-dependent manner Cell Growth Differ 8 1161 1169 (Pubitemid 27481652)
3. B Baccetti G Collodel P Piomboni 1996 Apoptosis in human ejaculated sperm cells J Submicrosc Cytol Pathol 28 587 596
4. D Behne H Weiler A Kyriakopoulos 1996 Effects of selenium deficiency on testicular morphology and function in rats J Reprod Fertil 106 291 297
5. RF Burk 1987 Production of selenium deficiency in the rat Methods Enzymol 143 307 313 (Pubitemid 18105253)
6. NS Chandel MG Vander Heiden CB Thompson PT Schumacker 2000 Redox regulation of p53 during hypoxia Oncogene 19 3840 3848 (Pubitemid 30658974)
7. M Daugaard M Jaatela M Rohde 2005 Hsp70-2 is required for tumor cell growth and survival Cell Cycle 4 7 877 880 (Pubitemid 41359749)
8. DJ Dix JW Allen BW Collins C Mori N Nakamura P Poorman-Allen EH Goulding EM Eddy 1996 Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility Proc Natl Acad Sci USA 93 3264 3268 (Pubitemid 26125606)
9. S Dorthe J Jutta H Guido T Klauf-Rudiger 2005 Radiation treatment of acute inflammation in mice Int J Radiat Biol 81 657 667
10. EM Eddy 1994 Role of heat shock protein HSP70-2 in spermatogenesis Rev Reprod 4 23 30
11. W Edelmann PE Cohen M Kane K Lau B Morrow S Benett A Umar T Kunkel G Cattoretti R Chaganti JW Pollard RD Kolodner R Kucherlapati 1996 Meiotic pachytene arrest in MLH1-deficient mice Cell 85 1125 1134 (Pubitemid 26231177)
12. A Fischer J Pallauf K Gohil SU Weber L Packer G Rimbach 2001 Effect of selenium and vitamin E deficiency on differential gene expression in rat liver Biochem Biophys Res Commun 285 2 470 475 (Pubitemid 32918094)
13. Flohe L, Brigelius-Flohe R, Maiorino M, Roveri A, Wissing J, Urcini F (2001) Selenium and male reproduction. In: Hatfield DL (ed) Selenium: its molecular biology and role in human health, Kluwer, Norwell, Chp. 22, pp 273-281
14. PJ Hissin R Hilf 1976 A fulorometric method for determination of oxidized and reduced glutathione in tissues Anal Biochem 74 214 226
15. G Huszar K Stone D Dix L Vigue 2000 Putative creatine kinase M-isoform in human sperm is identified as the 70-kilodalton heat shock protein Hsp A2 Biol Reprod 63 925 932 (Pubitemid 30659291)
16. SA Innocente JL Abrahamson JP Cogswell JM Lee 1999 p53 regulates a G2 checkpoint through cyclin B1 Proc Natl Acad Sci USA 96 2147 2152 (Pubitemid 29117882)
17. DS Irvine JP Twigg EL Gordon N Fulton PA Milne RJ Aitken 2000 DNA integrity in human spermatozoa: relationships with semen quality J Androl 21 33 44 (Pubitemid 30069079)
18. R Kaur V Parshad 1994 Effects of dietary selenium on differentiation, morphology and functions of spermatozoa of the house mouse, rat, Rattus rattus L. Mutat Res 309 29 35 (Pubitemid 24233069)
19. N Kaushal MP Bansal 2007 Inhibition of CDC2/Cyclin B1 in response to selenium-induced oxidative stress during spermatogenesis: potential role of Cdc25c and p21 Mol Cell Biochem 298 1-2 139 150 (Pubitemid 46605291)
20. N Kaushal MP Bansal 2007 Inhibition of CDC2/Cyclin B1 in response to selenium-induced oxidative stress during spermatogenesis: potential role of Cdc25c and p21 Mol Cell Biochem 298 1-2 139 150 (Pubitemid 46605291)
21. JM Kim SR Ghosh A Well BR Zirkin 2001 Caspase-3 and caspase-activated deoxyribonuclease are associated with testicular germ cell apoptosis resulting from reduced intratesticular testosterone Endocrinology 142 3809 3816 (Pubitemid 32802651)
22. Kumar TR, Doreswamy K, Shrilatha B and Muralidhara (2002) Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects of fertility. Mutat Res 513:103-111 (Pubitemid 33096329)
23. PJ Moos K Edes P Cassidy E Massuda FA Fitzpatrick 2003 Electrophilic prostaglandins and lipid aldehydes repress redox sensitive transcription factors p53 and HIF by impairing the selenoprotein thioredoxin reductase J Biol Chem 278 745 750 (Pubitemid 36790745)
24. C Mori N Nakamura DJ Dix M Fujioka S Nakagawa K Shiota EM Eddy 1997 Morphological analysis of germ cell apoptosis during postnatal testis development in normal and Hsp 70-2 knockout mice Dev Dyn 208 125 136 (Pubitemid 27030490)
25. L Rao B Puschner TA Prolla 2001 Gene expression profiling of low selenium status in the mouse intestine: transcriptional activation of genes linked to DNA damage, cell cycle control and oxidative stress J Nutr 131 3175 3181 (Pubitemid 33136131)
26. D Schwartz N Goldfinger V Rotter 1993 Expression of p53 protein in spermatogenesis is confined to the tetraploid pachytene primary spermatocytes Oncogene 8 1487 1494
27. YR Seo MR Kelley ML Smith 2002 Selenomethionine regulation of p53 by a ref1-dependent redox mechanism Proc Natl Acad Sci USA 99 14548 14553 (Pubitemid 35257708)
28. H Shen C Yang W Ding J Liu C Ong 2001 Superoxide radical-initiated apoptotic signaling pathway in selenite-treated HepG2 cell: mitochondria serve as the main target Free Radic Biol Med 30 9 21 (Pubitemid 32008084)
29. WY Son SH Hwang CT Han JH Lee S Kim YC Kim 1999 Specific expression of heat shock protein HspA2 in human male germ cells Mol Hum Reprod 5 1122 1126
30. JE Spallholz 1994 On the nature of selenium toxicity and carcinostatic activity Free Radic Biol Med 17 1 45 64 (Pubitemid 24212711)
31. JE Spallholz BJ Shriver TW Reid 2001 Dimethyldiselenide and methylseleninic acid generates superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of l-selenomethionine and l-Se-methylselenocysteine Nutr Cancer 40 1 34 41 (Pubitemid 34037512)
32. J Yun HD Chae HE Choi J Chung HS Yoo MH Han DY Shin 1999 p53 negatively regulates cdc2 transcription via the CCAAT-binding NF-Y transcription factor J Biol Chem 274 29677 29682
33. ZF Zakeri DJ Wolgemuth CR Hung 1988 Identification and sequence analysis of a new member of the mouse HSP70 gene family and characterization of its unique cellular and developmental pattern of expression in the male germ line Mol Cell Biol 8 2925 2932 (Pubitemid 18165075)
34. D Zhu DJ Dix EM Eddy 1997 HSP70-2 is required for CDC2 kinase activity in meiosis I of mouse spermatocytes Development 124 3007 3014 (Pubitemid 27370915)
35. A Zini R Bielcki D Phang MT Zenzes 2001 Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile me Fertil Steril 75 674 677 (Pubitemid 32273501)