Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3264-3268

  Dix, David J ^a,c,f   Allen, James W ^b   Collins, Barbara W ^b   Mori, Chisato ^d   Nakamura, Noriko ^d   Poorman Allen, Patricia ^e   Goulding, Eugenia H ^c   Eddy, E M ^c  

^a Gamete and Early Embryo Biol Branch   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d KYOTO UNIVERSITY   (Japan)

^e GLAXOSMITHKLINE   (United States)

^f U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

gametogenesis; heat shock protein; programmed cell death; spermatogenesis; stress protein

Indexed keywords

HEAT SHOCK PROTEIN;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; FEMALE; GENE TARGETING; GERM CELL; HAMSTER; MALE; MALE INFERTILITY; MEIOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPHASE; PROTEIN SYNTHESIS; SPERMATOGENESIS; SYNAPTONEMAL COMPLEX;

ANIMALS; APOPTOSIS; CRICETINAE; FEMALE; GENE TARGETING; HSP70 HEAT-SHOCK PROTEINS; INFERTILITY, MALE; MALE; MEIOSIS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; PREGNANCY; SPERMATOCYTES; SPERMATOGENESIS; SYNAPTONEMAL COMPLEX; TESTIS;

EID: 0029991234     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3264     Document Type: Article

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