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We are aware of only one example of nucleophilic attack on such species, described by Yagupolskii and co-workers concerning the specific reaction of trifluoromethanesulfonamine with trifluoromethyl phenyl sulfoxide: N. V. Kondratenko, V. I. Popov, G. N. Timofeeva, N. V. Ignat'ev, L. M. Yagupolskii, Zh. Org. KMm. 1984, 20, 2599-2604;
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a) We are aware of only one example of nucleophilic attack on such species, described by Yagupolskii and co-workers concerning the specific reaction of trifluoromethanesulfonamine with trifluoromethyl phenyl sulfoxide: N. V. Kondratenko, V. I. Popov, G. N. Timofeeva, N. V. Ignat'ev, L. M. Yagupolskii, Zh. Org. KMm. 1984, 20, 2599-2604;
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and references cited herein
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67650884003
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19F NMR spectroscopy. See the corresponding spectra in Supporting Information.
-
19F NMR spectroscopy. See the corresponding spectra in Supporting Information.
-
-
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35
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67650874174
-
-
X-ray structure of sulfoximine 23 has also been obtained. The crystal data for 5, 10 and 23 are detailed in the Supporting Information. CCDC-724941 (5), -724942 (10) and -724943 (23) contain the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data-request/cif.
-
X-ray structure of sulfoximine 23 has also been obtained. The crystal data for 5, 10 and 23 are detailed in the Supporting Information. CCDC-724941 (5), -724942 (10) and -724943 (23) contain the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data-request/cif.
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46
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67650916279
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Safety remarks When this reaction is conducted on a large scale (1.0 g of sulfoxide or more), the addition of sodium azide can set the reaction mixture on fire.
-
Safety remarks When this reaction is conducted on a large scale (1.0 g of sulfoxide or more), the addition of sodium azide can set the reaction mixture on fire.
-
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48
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0000057992
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67650913211
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[18.19]), probably due to secondary oxidation process on benzylic position.
-
[18.19]), probably due to secondary oxidation process on benzylic position.
-
-
-
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53
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0001780558
-
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The sulfoxides have been prepared from the corresponding thiol by our previously described methods: a A. Anselmi, J.C. Blazejewski, M. Tordeux, C. Wakselman, J. Fluorine Chem. 2000, 105, 41-44;
-
The sulfoxides have been prepared from the corresponding thiol by our previously described methods: a) A. Anselmi, J.C. Blazejewski, M. Tordeux, C. Wakselman, J. Fluorine Chem. 2000, 105, 41-44;
-
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54
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0142185103
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E. Magnier, M. Tordeux, R. Goumont, K. Magder, C Wakselman, J. Fluorine Chem. 2003, 124, 55-59. See also the Supporting Information.
-
b) E. Magnier, M. Tordeux, R. Goumont, K. Magder, C Wakselman, J. Fluorine Chem. 2003, 124, 55-59. See also the Supporting Information.
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-
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