Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Aβ accumulation in transgenic APP-C100 mice

Cellular and Molecular Neurobiology

Volumn 29, Issue 5, 2009, Pages 757-767

  Maynard, Christa J ^a,b,d   Cappai, Roberto ^a,b   Volitakis, Irene ^b   Laughton, Katrina M ^a,b   Masters, Colin L ^a,b   Bush, Ashley I ^a,b,c   Li, Qiao Xin ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Alzheimer's disease; Amyloid beta peptide; APP C100; Copper; Zinc

Indexed keywords

AMYLOID PRECURSOR PROTEIN; ANTIOXIDANT; CARBOXY TERMINAL TELOPEPTIDE; COPPER; DRINKING WATER; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; DIETARY INTAKE; ENZYME LINKED IMMUNOSORBENT ASSAY; GLIOSIS; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; METAL HOMEOSTASIS; MOUSE; NERVE CELL; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOLUBILITY; TISSUE HOMOGENATE; TRANSGENIC MOUSE; UPREGULATION; WESTERN BLOTTING;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BIOLOGICAL MARKERS; BRAIN; COPPER; DIET; DRINKING; ENVIRONMENTAL EXPOSURE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEEDING BEHAVIOR; GLIAL FIBRILLARY ACIDIC PROTEIN; HOMEOSTASIS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; NEURONS; STRESS, PHYSIOLOGICAL; ZINC;

MUS; MUS MUSCULUS;

EID: 67650831663     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-009-9401-7     Document Type: Article

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