The effect of wasabi rhizome extract on atopic dermatitis-like symptoms in HR-1 hairless mice

Journal of Nutritional Science and Vitaminology

Volumn 55, Issue 2, 2009, Pages 195-200

  Nagai, Masashi ^a   Okunishi, Isao ^a  

^a Kinjirushi Co Ltd   (Japan)

Author keywords

6 methylsulfinylhexyl isothiocyanate; Atopic dermatitis; HR 1 hairless mice; Wasabi

Indexed keywords

CD4 ANTIGEN; DERMATOLOGICAL AGENT; EOTAXIN; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN 4; INTERLEUKIN 5; PLANT EXTRACT; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG; WASABI EXTRACT; ANTIBODY; BETA CHEMOKINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DIET THERAPY; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; HISTOPATHOLOGY; MALE; MEDIATOR RELEASE; MOUSE; NONHUMAN; PLANT ROOT; SKIN PRURITUS; WASABI; ANIMAL; ANIMAL BEHAVIOR; BLOOD; BRASSICACEAE; CALORIC INTAKE; DISEASE MODEL; DRUG EFFECT; HAIRLESS MOUSE; IMMUNOLOGY; PHYTOTHERAPY; PRURITUS; RHIZOME; SKIN; WEIGHT GAIN;

EUTREMA WASABI; MUS;

ANIMALS; ANTIBODIES; BEHAVIOR, ANIMAL; BRASSICACEAE; CHEMOKINE CCL17; CHEMOKINES, CC; DERMATITIS, ATOPIC; DISEASE MODELS, ANIMAL; ENERGY INTAKE; HISTAMINE; IMMUNOGLOBULIN E; MALE; MICE; MICE, HAIRLESS; PHYTOTHERAPY; PLANT EXTRACTS; PRURITUS; RHIZOME; SKIN; WEIGHT GAIN;

EID: 67650760277     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.55.195     Document Type: Article

References (29)

1. Furue M, Saeki H, Furukawa F, Hide M, Ohtsuki M, Nakamura T, Sasaki R, Suto H, Takehara K. 2008. Guideline for management of atopic dermatitis. Nippon Hihuka Gakkai Zasshi 118: 325-342 (in Japanese).
2. Hoffman DR, Yamamoto FY, Geller B, Haddad Z. 1975. Specific IgE antibodies in atopic eczema. J Allergy Clin Immunol 55: 256-267.
3. Ring J. 1983. Plasma histamine concentrations in atopic eczema. Clin Allergy 13: 545-552. (Pubitemid 14230851)
4. Welle MM, Olivry T, Grimm S, Suter M. 1999. Mast cell density and subtypes in the skin of dogs with atopic dermatitis. J Comp Pathol 120: 187-197. (Pubitemid 29082004)
5. Inada N, Shoji J, Tabuchi K, Saito K, Sawa M. 2004. Histological study on mast cells in conjunctiva of NC/Nga mice. Jpn J Ophthalmol 48:189-194. (Pubitemid 38691424)
6. + lymphocytes into lesional atopic dermatitis skin. J Invest Dermatol 115: 640-646.
7. Dworzak MN, Fröschl G, Printz D, Fleischer C, Pötschger U, Fritsch G, Gadner H, Emminger W. 1999. Skin-associated lymphocytes in the peripheral blood of patients with atopic dermatitis: signs of subset expansion and stimulation. J Allergy Clin Immunol 103: 901-906. (Pubitemid 29297595)
8. Miyamasu M, Nakajima T, Misaki Y, Izumi S, Tsuno N, Kasahara T, Yamamoto K, Morita Y, Hirai K. 1999. Dermal fibroblasts represent a potent major source of human eotaxin: In vitro production and cytokine-mediated regulation. Cytokine 11: 751-758. (Pubitemid 29460473)
9. Ring J, Bieber T, Vieluf D, Kunz B, Przybilla B. 1991. Atopic eczema, Langerhans cells and allergy. Int Arch Allergy Appl Immunol 94: 194-201.
10. Gleich GJ, Loegering DA, Kueppers F, Bajaj SP, Mann KG. 1974. Physiochemical and biological properties of the major basic protein from guinea pig eosinophil granules. J Exp Med 140: 313-332.
11. Kakinuma T, Nakamura K, Wakugawa M, Mitsui H, Tada Y, Saeki H, Torii H, Asahina A, Onai N, Matsushima K, Tamaki K. 2001. Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity. J Allergy Clin Immunol 107: 535-541. (Pubitemid 32210037)
12. Fujisawa T, Fujisawa R, Kato Y, Nakayama T, Morita A, Katsumata H, Nishimori H, Iguchi K, Kamiya H, Gray PW, Chantry D, Suzuki R, Yoshie O. 2002. Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in patients with atopic dermatitis. J Allergy Clin Immunol 110: 139-146. (Pubitemid 36132740)
13. Jahnz-Rozyk K, Targowski T, Paluchowska E, Owczarek W, Kucharczyk A. 2005. Serum thymus and activation-regulated chemokine, macrophage-derived chemokine and eotaxin as markers of severity of atopic dermatitis. Allergy 60: 685-688. (Pubitemid 40562477)
14. Omoto M, Gu LH, Sugiura H, Uehara M. 2000. Heterogeneity of dermal deposition of eosinophil granule major basic protein in acute lesions of atopic dermatitis. Arch Dermatol Res 292: 51-54. (Pubitemid 30160399)
15. Isshiki K, Tokuoka K, Mori R, Chiba S. 1992. Preliminary examination of allyl isothiocyanate vapor for food preservation. Biosci Biotechnol Biochem 56: 1476-1477.
16. Ono H, Tesaki S, Tanabe S, Watanabe M. 1998. 6-Methylsulfinylhexyl isothiocyanate and its homologues as food-originated compounds with antibacterial activity against Escherichia coli and Staphylococcus aureus. Biosci Biotechnol Biochem 62: 363-365.
17. Fukuchi Y, Kato Y, Okunishi I, Matsutani Y, Osawa T. 2004. 6-Methylsulfinylhexyl isothiocyanate, an antioxidant derived from Wasabia japonica Matsum, ameliorates diabetic nephropathy in type 2 diabetic mice. Food Sci Technol Res 10: 290-295. (Pubitemid 43034162)
18. Morimitsu Y, Hayashi K, Nakagawa Y, Horio F, Uchida K, Osawa T. 2000. Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, wasabi. Biofactors 13: 271-276. (Pubitemid 32107375)
19. Uto T, Fujii M, Hou D-X. 2005. 6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages. Biochem Pharmacol 70: 1211-1221. (Pubitemid 41317515)
20. Kubo M, Kambayashi Y, Takemoto K, Okuda J, Muto M, Ogino K. 2005. Reactive nitrogen species formation in eosinophils and imbalance in nitric oxide metabolism are involved in atopic dermatitis-like skin lesions in NC/Nga mice. Free Radic Res 39: 719-727. (Pubitemid 40959659)
21. Taniuchi S, Kojima T, Hara Mt K, Yamamoto A, Sasai M, Takahashi H, Kobayashi Y. 2001. Increased serum nitrate levels in infants with atopic dermatitis. Allergy 56: 693-695. (Pubitemid 32575446)
22. Fujii M, Tomozawa J, Mizutani N, Nabe T, Danno K, Kohno S. 2005. Atopic dermatitis-like pruritic skin inflammation caused by feeding a special diet to HR-1 hairless mice. Exp Dermatol 14: 460-468. (Pubitemid 40740398)
23. Akamatsu H, Makiura M, Yamamoto N, Yagami A, Shimizu Y, Matsunaga K. 2006. The effect of fexofenadine on pruritus in a mouse model (HR-ADf) of atopic dermatitis. J Int Med Res 34: 495-504. (Pubitemid 44756136)
24. Fujii M, Akita K, Mizutani N, Nabe T, Kohno S. 2007. Development of numerous nerve fibers in the epidermis of hairless mice with atopic dermatitis-like pruritic skin inflammation. J Pharmacol Sci 104: 243-251. (Pubitemid 47122472)
25. Makiura M, Akamatsu H, Akita H, Yagami A, Shimizu Y, Eiro H, Kuramoto M, Suzuki K, Matsunaga K. 2004. Atopic dermatitis-like symptoms in HR-1 hairless mice fed a diet low in magnesium and zinc. J Int Med Res 32: 392-399. (Pubitemid 39069509)
26. Morimitsu Y, Nakagawa Y, Hayashi K, Fujii H, Kumagai T, Nakamura Y, Osawa T, Horio F, Itoh K, Iida K, Yamamoto M, Uchida K. 2002. A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway. J Biol Chem 277: 3456-3463. (Pubitemid 34953214)
27. Uto T, Fujii M, Hou D-X. 2005. Inhibition of lipopolysaccharide-induced cyclooxygenase-2 transcription by 6-(methylsulfinyl)hexyl isothiocyanate, a chemopreventive compound from Wasabia japonica (Miq.) Matsumura, in mouse macrophages. Biochem Pharmacol 70: 1772-1784. (Pubitemid 41612008)
28. Heijink IH, Marcel Kies P, van Oosterhout AJ, Postma DS, Kauffman HF, Vellenga E. 2007. Der p, IL-4, and TGF-β cooperatively induce EGFR-dependent TARC expression in airway epithelium. Am J Respir Cell Mol Biol 36: 351-359. (Pubitemid 46365286)
29. Wong CK, Zhang JP, Ip WK, Lam CW. 2002. Activation of p38 mitogen-activated protein kinase and nuclear factor-kappaB in tumour necrosis factor-induced eotaxin release of human eosinophils. Clin Exp Immunol 128: 483-489.