메뉴 건너뛰기




Volumn 36, Issue 3, 2009, Pages 323-330

Effects of pcsk9 siRNA on THP-1 derived macrophages apoptosis induced by oxLDL

Author keywords

Apoptosis; Macrophages; Oxidized low density lipoprotein; Proprotein convertase subtilisin kexin 9 neural apoptosis regulated convertase 1; Small interfering RNA

Indexed keywords


EID: 67650751404     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2008.00427     Document Type: Article
Times cited : (11)

References (18)
  • 1
    • 0037192792 scopus 로고    scopus 로고
    • Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: Ectodomain shedding requires SKI-lactivity
    • Elagoz A, Benjannel S, Mammarbassi A, et al. Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: ectodomain shedding requires SKI-lactivity. J Biol Chem, 2002, 277 (13): 11265-11275
    • (2002) J Biol Chem , vol.277 , Issue.13 , pp. 11265-11275
    • Elagoz, A.1    Benjannel, S.2    Mammarbassi, A.3
  • 2
    • 0037417807 scopus 로고    scopus 로고
    • Seidah N G, Benjannet S, Wickham L, et al. The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.Proc Natl Acad Sci USA, 2003, 100(3): 928̃933
    • Seidah N G, Benjannet S, Wickham L, et al. The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation.Proc Natl Acad Sci USA, 2003, 100(3): 928̃933
  • 3
    • 13844310887 scopus 로고    scopus 로고
    • Over expression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment
    • Maxwell K N, Fisher E A, Breslow J L, et al. Over expression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment. Proc Natl Acad Sci USA, 2005, 102(6): 2069-2074
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.6 , pp. 2069-2074
    • Maxwell, K.N.1    Fisher, E.A.2    Breslow, J.L.3
  • 5
    • 33745875635 scopus 로고    scopus 로고
    • Implication of the proprotein convertase PCSK9/NARC-1 in the development of the nervous system
    • Poirier S, Prat A, Marcinkiewicz E, et al. Implication of the proprotein convertase PCSK9/NARC-1 in the development of the nervous system. J Neurochem, 2006, 98(3): 838-850
    • (2006) J Neurochem , vol.98 , Issue.3 , pp. 838-850
    • Poirier, S.1    Prat, A.2    Marcinkiewicz, E.3
  • 6
    • 48549091854 scopus 로고    scopus 로고
    • PCSK9 function and physiology
    • Peterson A S, Fong L G, Young S G. PCSK9 function and physiology. J Lipid Res, 2008, 49(6): 1152-1156
    • (2008) J Lipid Res , vol.49 , Issue.6 , pp. 1152-1156
    • Peterson, A.S.1    Fong, L.G.2    Young, S.G.3
  • 7
    • 33750974195 scopus 로고    scopus 로고
    • Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase
    • Bingham B, Shen R, Kotnis S, et al. Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase. Cytometry A, 2006, 69(11): 1123-1131
    • (2006) Cytometry A , vol.69 , Issue.11 , pp. 1123-1131
    • Bingham, B.1    Shen, R.2    Kotnis, S.3
  • 8
    • 33645225775 scopus 로고    scopus 로고
    • Lowing LDL-not only how low, but how long?
    • Brown M S, Goldstein J L. Lowing LDL-not only how low, but how long?. Science, 2006, 311(5768): 1721-1723
    • (2006) Science , vol.311 , Issue.5768 , pp. 1721-1723
    • Brown, M.S.1    Goldstein, J.L.2
  • 10
    • 0029807088 scopus 로고    scopus 로고
    • Macrophage and atherosclerotic plaque stability
    • Libby P, Geng Y J, Aikawa M, et al. Macrophage and atherosclerotic plaque stability. Curr Opin Lipidol, 1996, 7(5): 330-335
    • (1996) Curr Opin Lipidol , vol.7 , Issue.5 , pp. 330-335
    • Libby, P.1    Geng, Y.J.2    Aikawa, M.3
  • 11
    • 11844262719 scopus 로고    scopus 로고
    • Macrophage activation in atherosclerosis: Pathogenesis and pharmacology of plaque rupture
    • Boyle J J. Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture. Curr Vasc Pharmacol, 2005, 3 (1): 63-68
    • (2005) Curr Vasc Pharmacol , vol.3 , Issue.1 , pp. 63-68
    • Boyle, J.J.1
  • 12
    • 46349103159 scopus 로고    scopus 로고
    • Secreted proprotein convertase subtilisin/kexin type 9 reduces both hepatic and extrahepatic low-density lipoprotein receptors in vivo
    • Schmidt R J, Beyer T P, Bensch W R, et al. Secreted proprotein convertase subtilisin/kexin type 9 reduces both hepatic and extrahepatic low-density lipoprotein receptors in vivo. Biochem Biophys Res Commun, 2008, 370(4): 634-640
    • (2008) Biochem Biophys Res Commun , vol.370 , Issue.4 , pp. 634-640
    • Schmidt, R.J.1    Beyer, T.P.2    Bensch, W.R.3
  • 14
    • 0033793081 scopus 로고    scopus 로고
    • RNA interference: Genetic wand and genetic watchdog
    • Bosher J M, Labouesse M. RNA interference: genetic wand and genetic watchdog. Nat Cell Biol, 2000, 2(2): E31-E36
    • (2000) Nat Cell Biol , vol.2 , Issue.2
    • Bosher, J.M.1    Labouesse, M.2
  • 15
    • 17444365809 scopus 로고    scopus 로고
    • Local RNA target tructure influences siRNA efficacy: A systematic global analysis
    • Overhoff M, Alken M, Far R K, et al. Local RNA target tructure influences siRNA efficacy: A systematic global analysis. J Mol Biol, 2005, 348(4): 871-881
    • (2005) J Mol Biol , vol.348 , Issue.4 , pp. 871-881
    • Overhoff, M.1    Alken, M.2    Far, R.K.3
  • 16
    • 0344321890 scopus 로고    scopus 로고
    • RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells
    • Wilson J A, Jayasena S, Khvorova A, et al. RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells. Proc Natl Acad Sci USA, 2003, 100 (5): 2783-2788
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.5 , pp. 2783-2788
    • Wilson, J.A.1    Jayasena, S.2    Khvorova, A.3
  • 17
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • Bröker L E, Kruyt F A, Giaccone G. Cell death independent of caspases: a review. Clin Cancer Res, 2005, 11(9): 3155-3162
    • (2005) Clin Cancer Res , vol.11 , Issue.9 , pp. 3155-3162
    • Bröker, L.E.1    Kruyt, F.A.2    Giaccone, G.3
  • 18
    • 34250867475 scopus 로고    scopus 로고
    • The emerging role of serine proteases in apoptosis
    • Moffitt K L, Martin S L, Walker B. The emerging role of serine proteases in apoptosis. Biochem Soc Trans, 2007, 35(Pt 3): 559 - 560
    • (2007) Biochem Soc Trans , vol.35 , Issue.PART 3 , pp. 559-560
    • Moffitt, K.L.1    Martin, S.L.2    Walker, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.