Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells

Chemico-Biological Interactions

Volumn 181, Issue 1, 2009, Pages 52-60

  Matsunaga, Toshiyuki ^a   Arakaki, Marina ^a   Kamiya, Tetsuro ^a   Endo, Satoshi ^a   El Kabbani, Ossama ^b   Hara, Akira ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^b MONASH UNIVERSITY   (Australia)

Author keywords

9,10 Phenanthrenequinone; Aldo keto reductase 1C3; Apoptosis; Endothelial cells; Oxidative stress; Redox cycling

Indexed keywords

ALDO KETO REDUCTASE 1C3; CASPASE; FLUFENAMIC ACID; GLUTATHIONE; INDOMETACIN; MESSENGER RNA; OXIDOREDUCTASE; PHENANTHRENEQUINONE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; UNCLASSIFIED DRUG;

AORTA; APOPTOSIS; ARTICLE; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

3-HYDROXYSTEROID DEHYDROGENASES; APOPTOSIS; BASE SEQUENCE; CELLS, CULTURED; DNA PRIMERS; ENDOTHELIUM, VASCULAR; HUMANS; HYDROXYPROSTAGLANDIN DEHYDROGENASES; OXIDATION-REDUCTION; PHENANTHRENES; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES;

EID: 67650663252     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.05.005     Document Type: Article

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