Substrate binding tunes conformational flexibility and kinetic stability of an amino acid antiporter

Journal of Biological Chemistry

Volumn 284, Issue 28, 2009, Pages 18651-18663

  Bippes, Christian A ^a   Zeltina, Antra ^a   Casagrande, Fabio ^b   Ratera, Merce ^c   Palacin, Manuel ^c   Muller, Daniel J ^a   Fotiadis, Dimitrios ^d  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTERS; BACILLUS SUBTILIS; BOUND STATE; CONFORMATIONAL FLEXIBILITY; FLEXIBLE CONFORMATION; KINETIC STABILITY; LOCALIZED INTERACTION; MEMBRANE SURFACE; RAPID SWITCHING; SINGLE-MOLECULE DYNAMICS; SUBSTRATE BINDING; SUBSTRATE-BOUND; UNBOUND STATE; WEAK INTERACTIONS; WORKING MODELS;

AMINES; AMINO ACIDS; BACTERIOLOGY; BINDING ENERGY; CELL MEMBRANES; CONFORMATIONS; CYTOLOGY; ENERGY BARRIERS; MECHANICAL PROPERTIES; ORGANIC ACIDS;

SUBSTRATES;

ANTIPORTER; SERINE THREONINE ANTIPORTER; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; CONTROLLED STUDY; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; SPECTROSCOPY;

AMINO ACIDS; ANTIPORTERS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BINDING SITES; BIOLOGICAL TRANSPORT; BIOPHYSICS; CLONING, MOLECULAR; ION TRANSPORT; KINETICS; MOLECULAR CONFORMATION; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

BACILLUS SUBTILIS;

EID: 67650632375     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.004267     Document Type: Article

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