Endotoxin tolerance in sepsis: Concentration-dependent augmentation or inhibition of LPS-stimulated macrophage TNF secretion by LPS pretreatment

Journal of Trauma - Injury, Infection and Critical Care

Volumn 65, Issue 4, 2008, Pages 893-898

  West, Michael A ^a   Koons, Ann ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Immunoparalysis; Lipopolysaccharide; Macrophage activation; Peptidoglycan; Tumor necrosis factor

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; ENDOTOXIN; TUMOR NECROSIS FACTOR; ENDOTOXIN, ESCHERICHIA COLI; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BACTERIUM; CHI SQUARE TEST; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; EXPOSURE; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SEPSIS; SUPERNATANT; TREATMENT DURATION; ANIMAL; CELL CULTURE; CHI SQUARE DISTRIBUTION; DOSE RESPONSE; DRUG EFFECT; METABOLISM; MICROBIOLOGY; MONOCYTE; PATHOPHYSIOLOGY; PROBABILITY; SECRETION; SENSITIVITY AND SPECIFICITY;

ANIMALS; CELLS, CULTURED; CHI-SQUARE DISTRIBUTION; CULTURE MEDIA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; PROBABILITY; SENSITIVITY AND SPECIFICITY; SEPSIS; TUMOR NECROSIS FACTORS;

EID: 67650620771     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e3181877fde     Document Type: Article

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