Anti-inflammatory cytokines induce lipopolysaccharide tolerance in human monocytes without modifying toll-like receptor 4 membrane expression

Scandinavian Journal of Immunology

Volumn 59, Issue 6, 2004, Pages 553-558

  Moreno, C ^a   Merino, J ^a   Vazquez B ^a   Ramirez N ^a   Echeverria A ^a   Pastor, F ^a   Sanchez Ibarrola A ^a,b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; INCUBATION TIME; MALE; MODEL; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION;

ADULT; CELLS, CULTURED; CYTOKINES; FEMALE; HUMANS; IMMUNE TOLERANCE; LIPOPOLYSACCHARIDES; MALE; MEMBRANE GLYCOPROTEINS; MONOCYTES; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 2942703977     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0300-9475.2004.01445.x     Document Type: Article

References (23)

1. Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol 2001;2:675-80.
2. Janeway CA, Medzhitov R. Innate immune recognition. Annu Rev Immunol 2002;20:197-216.
3. Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature 2000;406:782-7.
4. Nomura F, Akashi S, Sakao Y et al. Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J Immunol 2000;164:3476-9.
5. Akashi S, Shimazu R, Ogata H et al. Cell surface expression and lipopolysaccharide signaling via the Toll-like receptor 4-MD2 complex on mouse peritoneal macrophages. J Immunol 2000;164:3471-5.
6. Visintin A, Mazzoni A, Spitzer JH et al. Regulation of Toll-like receptors in human monocytes and dendritic cells. J Immunol 2001;166:249-55.
7. Bosisio D, Polentarutti N, Sironi M et al. Stimulation of Toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood 2002;99:3427-31.
8. Sabroe I, Jones E, Usher L et al. Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses. J Immunol 2002;168:4701-10.
9. Randow F, Syrbe U, Meisel CH et al. Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor β. J Exp Med 1995;181:1887-92.
10. Warwick-Davies J, Lowrie D, Cole P. Selective deactivation of human monocyte functions by TGF-β. J Immunol 1995;155:3186-93.
11. Muzio M, Bosisio D, Polentarutti N et al. Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol 2000; 164:5998-6004.
12. Hoshino K, Takeuchi O, Kawai T et al. Toll-like receptor 4 (TLR4)-deficient mice are hyporresponsive to lipopolysacccharide: evidence for TLR4 as the Lps gene product. J Immunol 1999;162:3749-52.
13. Medvedev AE, Lentschat A, Wahl LM et al. Dysregulation of LPS-induced Toll-like receptor 4-MyD88 complex formation and IL-1 receptor associated kinase 1 activation in endotoxin-tolerant cells. J Immunol 2002;169:5209-16.
14. Dobrovolskaia MA, Medvedev AE, Thomas KE et al. Induction of in vitro reprogramming by Toll-like receptor (TLR) 2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-κB signaling pathway components. J Immunol 2003;170:508-19.
15. Li L, Cousart S, Hu J, McCall CE. Characterization of interleukin 1 receptor associated kinase in normal and endotoxin-tolerant cells. J Biol Chem 2000;275:23340-5.
16. Henneke P, Golenbock DT. Tirap: how Toll receptors fraternize. Nat Immunol 2001;2:828-30.
17. Kobayashi K, Inohara N, Hernandez LD et al. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 2002;416:194-9.
18. Suzuki N, Suzuki S, Duncan GS et al. Severe impairment of interleukine 1 and Toll-like receptor signaling in mice lacking IRAK-4. Nature 2002;416:750-6.
19. Jacinto R, Hartung T, McCall C, Li L. Lipopolisaccharide- and lipoteichoic acid-induced tolerance and cross-tolerance: distinct alterations in IL-1 receptor-associated kinase. J Immunol 2002;168:6136-41.
20. 2 production. J Immunol 2003;170:158-66.
21. Pilette Ch, Ouadrhiri Y, Van Snick J et al. IL-9 inhibits oxidative burst and TNF-α release in lipopolysaccharide-stimulated human monocytes through TGF-β. J Immunol 2002;168:4103-11.
22. Medvedev AE, Henneke P, Schromm A et al. Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4. J Immunol 2001;167:2257-67.
23. Adib-Conquy M, Cavaillon JM. Gamma interferon and granulocyte/monocyte colony-stimulating factor prevent endotoxin tolerance in human monocytes by promoting interleukin-1 receptor-associated kinase expression and its association to MyD88 and not by modulating TLR4 expression. J Biol Chem 2002;277:27927-34.