Positional scanning for peptide secondary structure by systematic solid-phase synthesis of amino lactam peptides

Journal of the American Chemical Society

Volumn 131, Issue 22, 2009, Pages 7917-7927

  Jamieson, Andrew G ^a,c   Boutard, Nicolas ^a   Beauregard, Kim ^b   Bodas, Mandar S ^a,d   Ong, Huy ^a   Quiniou, Christiane ^b   Chemtob, Sylvain ^b   Lubell, William D ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

^c YALE UNIVERSITY   (United States)

^d Biocon Foundation   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC MODULATORS; BINDING AFFINITIES; BIOLOGICAL ACTIVITIES; BIOLOGICALLY ACTIVE PEPTIDES; CONFIGURATIONALLY; CONFORMATIONAL MOBILITY; GROWTH HORMONES; N-ALKYLATION; PEPTIDE SECONDARY STRUCTURES; PROTECTION STRATEGY; RAPID IDENTIFICATION; SECONDARY STRUCTURES; SIDE CHAINS; SOLID PHASE SYNTHESIS; SOLID-PHASE; SOLID-PHASE METHOD; THYMOCYTE;

ALKYLATION; AMIDES; AMINATION; BINDING ENERGY; HYDROCARBONS; PEPTIDES; SILANES; SYNTHESIS (CHEMICAL);

AMINES;

AMINO ACID DERIVATIVE; GHRELIN RECEPTOR; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; INTERLEUKIN 1 RECEPTOR; LACTAM DERIVATIVE; PEPTIDE; AMINO ACID; FLUORENE DERIVATIVE; GROWTH HORMONE RELEASING HEXAPEPTIDE; LACTAM; N(ALPHA) FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS; N(ALPHA)-FLUORENYLMETHYLOXYCARBONYLAMINO ACIDS; OLIGOPEPTIDE; SULFONAMIDE;

ALKYLATION; ALLOSTERISM; ANIMAL CELL; ANNULATION REACTION; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CELL PROLIFERATION; COMPETITIVE INHIBITION; CONFORMATION; MICROWAVE COOKING; NONHUMAN; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PROTEIN STRUCTURE; RAT; SOLID PHASE SYNTHESIS; THYMOCYTE; CHEMISTRY; PROTEIN SECONDARY STRUCTURE; STEREOISOMERISM; SYNTHESIS;

AMINO ACIDS; FLUORENES; LACTAMS; OLIGOPEPTIDES; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, INTERLEUKIN-1; STEREOISOMERISM; SULFONAMIDES;

EID: 67650549812     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9010628     Document Type: Article

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