Expression profiling of genes involved in collagen turnover in tendons from cerebral palsy patients

Connective Tissue Research

Volumn 50, Issue 3, 2009, Pages 203-208

  Gagliano, Nicoletta ^a   Pelillo, Francesco ^b   Chiriva Internati, Maurizio ^c   Picciolini, Odoardo ^d   Costa, Francesco ^a   Schutt Jr , Robert C ^c   Gioia, Magda ^a   Portinaro, Nicola ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^d FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Cerebral Palsy; Collagen Turnover; Matrix Metalloproteinases; SPARC; Spasticity; Tendons

Indexed keywords

COLLAGEN; COLLAGEN TYPE 1 ALPHA2; INTERSTITIAL COLLAGENASE; MESSENGER RNA; OSTEONECTIN; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE; PROCOLLAGEN LYSINE 2 OXOGLUTARATE 5 DIOXYGENASE 2B; SCLEROPROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; ALPHA 2(I) COLLAGEN;

ADOLESCENT; ARTICLE; CEREBRAL PALSY; CLINICAL ARTICLE; COLLAGEN METABOLISM; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE SEQUENCE; GENETIC ANALYSIS; GRACILIS MUSCLE; HUMAN; MALE; MATURATION; PARAPLEGIA; PHENOTYPE; QUADRIPLEGIA; REAL TIME POLYMERASE CHAIN REACTION; SEMITENDINOUS MUSCLE; SPASTICITY; TENDON; BIOSYNTHESIS; EXTRACELLULAR MATRIX; GENETICS; METABOLISM;

ADOLESCENT; CEREBRAL PALSY; COLLAGEN; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MATRIX METALLOPROTEINASE 1; OSTEONECTIN; PROCOLLAGEN-LYSINE, 2-OXOGLUTARATE 5-DIOXYGENASE; RNA, MESSENGER; TENDONS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TRANSFORMING GROWTH FACTOR BETA1;

EID: 67650488989     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.1080/03008200802613630     Document Type: Article

References (32)

1. Egger, J., Kendall, B.E., Erdohazi, M., Lake, B.D., Wilson, J., and Brett, E.M. (1983). Involvement of the central nervous system in congenital muscular dystrophies. Dev. Med. Child. Neurol., 25, 32-42.
2. Benjamin,M., and Ralphs, J.R. (2000). The cell and developmental biology of tendons and ligaments. In.t Rev. Cytol., 196, 85-130.
3. Kannus, P. (2000). Structure of the tendon connective tissue. Scand. J. Med. Sci. Sports, 10, 312-320.
4. Silver, F.H., Christiansen, D., Snowhill, P.B., Chen, Y., and Landis, W.J. (2000). The role of mineral in the storage of elastic energy in turkey tendons. Biomacromolecules, 1, 180-185.
5. Silver, F.H., Freeman, J.W., and Seehra, G.P. (2003). Collagen selfassembly and the development of tendon mechanical properties. J. Biomechanics, 36, 1529-1553.
6. McNeilly, C.M., Banes, A.J., Benjamin, M., and Ralphs, J.R. (1996). Tendon cells in vivo form a three dimensional network of cell processes linked by gap junctions. J. Anat., 189, 593-600.
7. Chiquet, M. (1999). Regulation of extracellular matrix gene expression by mechanical stress. Matrix Biol., 18, 417-426.
8. Gillard, G.C., Reilly, H.C., Bell-Booth, P.G., and Flint, M.H. (1979). The influence of mechanical forces on the glycosaminoglycan content of the rabbit flexor digitorum profundus tendon. Connect. Tissue Res. 7, 37-46.
9. Woo, S.L., Gomez, M.A., Amiel, D., Ritter, M.A., Gelberman, R.H., and Akeson, W.H. (1981). The effects of exercise on the biomechanical and biochemical properties of swine digital flexor tendons. J. Biomech. Eng., 103, 51-56.
10. Woo, S.L., Gomez, M.A.,Woo,Y.K., andAkeson,W.H. (1982).Mechanical properties of tendons and ligaments. II. The relationships of immobilization and exercise on tissue remodeling. Biorheology, 19, 397-408.
11. Tipton, C.M., Vailas, A.C., andMatthes, R.D. (1986). Experimental studies on the influences of physical activity on ligaments, tendons and joints: A brief review. Acta Med. Scand., Suppl.711, 157-168.
12. Livak, K.J., and Schmittgen, T.D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(- delta deltaC(T)) method. Methods, 25, 402-408.
13. Jozsa, L., and Kannus, P. (1997). Effects of activity and inactivity on tendons. In Human tendons. L. Jozsa and L. Kannus (eds.), pp. 127-160 (Human kinetics: Champaign, IL).
14. Koman, L.A., Smith, B.P., and Shilt, J.S. (2004). Cerebral palsy. Lancet, 363, 1619-1631.
15. Evans, C.E., and Trail, I.A. (1998). Fibroblast-like cells from tendons differ from skin fibroblasts in their ability to form three-dimensional structures in vitro. J. Hand Surg. [Br.], 23, 633-641.
16. Berglund, M.,Wiig, M., Torstensson, M., Reno, C., and Hart, D.A. (2004). Assessment of mRNA levels for matrix molecules and TGF- beta1 in rabbit flexor and peroneus tendons reveals regional differences in steady-state expression. J. Hand Surg. [Br.], 29, 165-169.
17. Woessner, F.J. (1991). Matrix metalloproteinases and their inhibitors in connective tissue remodelling. FASEB J., 5, 2145-2154.
18. Sakai, T., and Gross, J. (1967). Some properties of the products of reaction of tadpole collagenase with collagen. Biochem., 6, 518-528.
19. Amiel, D.,Woo, S.L., Harwood, F.L., and Akeson,W. (1982). The effect of immobilization on collagen turnover in connective tissue: A biochemicalbiomechanical correlation. Acta Orthop. Scand., 53, 325-332.
20. Arnoczky, S.P., Tian, T., Lavagnino, M., and Gardner, K. (2004). Ex vivo static tensile loading inhibits MMP-1 expression in rat tail tendon cells through a cytoskeletally basedmechanotransductionmechanism. J. Orthop. Res., 22, 328-333.
21. Rley, G.P., Curry, V., DeGroot, J., van El, B., Verzijl, N., Hazleman, B.L., and Bank, R.A. (2002). Matrix metalloproteinase activities and their relationship with collagen remodelling in tendon pathology. Matrix Biol., 21, 185-195.
22. Riley, G.P. (2005). Gene expression and matrix turnover in overused and damaged tendons. Scand. J. Med. Sci. Sports, 15, 241-251.
23. Brew, K., Dinakarpandian, D., and Nagase, H. (2001). Tissue inhibitors of metalloproteinases: Evolution, structure and function. Biochim. Biophys. Acta, 1477, 267-283.
24. van der Slot, A.J., Zuurmond, A., van der Bogaerdt, A.J., Ulrich, M., Middelkoop, E.,Boers,W., Ronday, K., DeGroot, J., Huizinga,T., andBank, R.A. (2004). Increased formation of pyridoline cross-links due to highetr telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon. Matrix Biol., 23, 251-257.
25. Bornstein, P., and Sage, E.H. (2002). Matricellular proteins: Extracellular modulators of cell function. Curr. Opin. Cell. Biol. 14, 608-616.
26. Bradshaw, A.D., and Sage, E.H. (2001). SPARC: A matricellular protein that functions in cellular differentiation and tissue response to injury. J. Clin. Invest., 107, 1049-1054.
27. Brekken, R.A., and Sage, E.H. (2000). SPARC a matricellular protein: At the crossroads of cell-matrix communication. Matrix Biol., 19, 569- 580.
28. Ignotz, R.A., and Massague, J. (1986). Transforming growth factor-beta1 stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol. Chem., 261, 4337-4345.
29. Sporn, M.B., and Roberts, A.B. (1990). The transforming growth factor-βs: Past, present and future. Ann. NY Acad. Sci., 593, 1-6.
30. Border, W.A., and Ruoslahti, E. (1992). Transforming growth factor-β in disease: The dark side of tissue repair. J. Clin. Invest., 90, 1-7.
31. Gutierrez, J.A., and Perr, H.A. (1999). Mechanical stretch modulates TGFbeta1 and alpha1(I) collagen expression in fetal human intestinal smooth muscle cells. Am. J. Physiol., 277, G1074-G1080.
32. Heinemeier, K., Langberg, H., Olesen, J.L., and Kjaer, M. (2003). Role of TGF-beta1 in relation to exercise-induced type I collagen synthesis in human tendinous tissue. J. Appl. Physiol., 95, 2390-2397.