Failed interleukin-6 signal transduction in murine sepsis: Attenuation of hepatic glycoprotein 130 phosphorylation

Critical Care Medicine

Volumn 37, Issue 5, 2009, Pages 1729-1734

  Abcejo, Arnoley S ^a   Andrejko, Kenneth M ^a   Raj, Nichelle R ^a   Deutschman, Clifford S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Animal models; Cytokines; Janus kinase; Liver; Signal transducer and activator of transcription 3; Signal transduction

Indexed keywords

DNA; GLYCOPROTEIN; GLYCOPROTEIN 130; INTERLEUKIN 6; JANUS KINASE 1; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DNA BINDING; ENZYME PHOSPHORYLATION; FLUID RESUSCITATION; GEL MOBILITY SHIFT ASSAY; LIGATION; LIVER; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; PUNCTURE; SEPSIS; SHAM PROCEDURE; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; CYTOKINE RECEPTOR GP130; DISEASE MODELS, ANIMAL; ELECTROPHORESIS; IMMUNOBLOTTING; INTERLEUKIN-6; LIVER; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; RANDOM ALLOCATION; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SEPSIS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION;

EID: 67650483308     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31819dee81     Document Type: Article

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