Phenethyl pyridines with non-polar internal substitutents as selective ligands for estrogen receptor beta

European Journal of Medicinal Chemistry

Volumn 44, Issue 9, 2009, Pages 3560-3570

  Waibel, Michael ^a   Kieser, Karen J ^a   Carlson, Kathryn E ^a   Stossi, Fabio ^b   Katzenellenbogen, Benita S ^b   Katzenellenbogen, John A ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Estrogen receptor; Estrogen receptor beta; Hexestrol; Pyridine estrogen; Selective ligand; Stilbestrol

Indexed keywords

6 [1 ETHYL 2 (4 HYDROXYPHENYL)BUTYL]PYRIDIN 3 OL; 6 [1 ETHYL 2 (4 HYDROXYPHENYL)PROPYL]PYRIDIN 3 OL; ALKYL GROUP; BIBENZYL DERIVATIVE; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; LIGAND; PHENOL; PICOLINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRIDINOL; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIGAND BINDING; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

CELL LINE, TUMOR; ENDOMETRIAL NEOPLASMS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIGANDS; MOLECULAR STRUCTURE; PROTEIN BINDING; PYRIDINES; TRANSCRIPTION, GENETIC;

EID: 67650455954     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.03.013     Document Type: Article

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