Toward selective ERβ agonists for central nervous system disorders: Synthesis and characterization of aryl benzthiophenes

Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2002, Pages 1399-1401

  Schopfer, Ulrich ^a   Schoeffter, Philippe ^a   Bischoff, Serge F ^a   Nozulak, Joachim ^a   Feuerbach, Dominik ^a   Floersheim, Philipp ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

17ALPHA ESTRADIOL; BENZOTHIOPHENE DERIVATIVE; DIETHYLSTILBESTROL; ESTRADIOL; ESTROGEN DERIVATIVE; ESTROGEN RECEPTOR BETA; ESTRONE; GENISTEIN; RALOXIFENE; BENZOTHIOPHENE; ESTROGEN RECEPTOR; LIGAND; THIOPHENE DERIVATIVE;

ARTICLE; BREAST CARCINOMA; CELL CULTURE; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENDOMETRIUM CARCINOMA; HELA CELL; HUMAN; HUMAN CELL; LEARNING; LIGAND BINDING; MEMORY; MOOD; REPORTER GENE; STRUCTURE ANALYSIS; BINDING SITE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; LETTER; METABOLISM; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; BINDING SITES; CENTRAL NERVOUS SYSTEM DISEASES; CRYSTALLOGRAPHY, X-RAY; ESTROGEN RECEPTOR BETA; HELA CELLS; HUMANS; LIGANDS; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ESTROGEN; THIOPHENES; TUMOR CELLS, CULTURED;

EID: 0037187189     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm015577l     Document Type: Article

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