Dihydrotestosterone modulates spatial working-memory performance in male mice

Journal of Neurochemistry

Volumn 110, Issue 3, 2009, Pages 902-911

  Benice, Ted S ^a   Raber, Jacob ^a,b  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Anxiety; Cognition; Dihydrotestosterone; Spatial working memory

Indexed keywords

ANDROSTANOLONE;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CASTRATION; COGNITION; CONTROLLED STUDY; HORMONE ACTION; MALE; MAZE TEST; MEMORY CONSOLIDATION; MOTOR COORDINATION; MOUSE; NONHUMAN; OPEN FIELD TEST; PASSIVE AVOIDANCE; PRIORITY JOURNAL; RECOGNITION; REFERENCE MEMORY; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY;

ANIMALS; AVOIDANCE LEARNING; DIHYDROTESTOSTERONE; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; ORCHIECTOMY; PSYCHOMOTOR PERFORMANCE; RANDOM ALLOCATION; SPATIAL BEHAVIOR;

ANIMALIA; MUS; RATTUS;

EID: 67650434973     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06183.x     Document Type: Article

References (32)

1. Benice T. S. Raber J. (2008) Object recognition analysis in mice using nose-point digital video tracking. J. Neurosci. Methods 168, 422 430.
2. Benice T. S., Rizk A., Kohama S., Pfankuch T. Raber J. (2006) Sex-differences in age-related cognitive decline in C57BL/6J mice associated with increased brain microtubule-associated protein 2 and synaptophysin immunoreactivity. Neuroscience 137, 413 423. (Pubitemid 43031508)
3. Cherrier M. M., Asthana S., Plymate S. et al. (2001) Testosterone supplementation improves spatial and verbal memory in healthy older men. Neurology 57, 80 88. (Pubitemid 32634854)
4. Cherrier M. M., Anawalt B. D., Herbst K. L., Amory J. K., Craft S., Matsumoto A. M., Bremner W. J. Cherrier M. M. (2002) Cognitive effects of short-term manipulation of serum sex steroids in healthy young men. J. Clin. Endocrinol. Metab. 87, 3090 3096. (Pubitemid 34816350)
5. Cherrier M. M., Rose A. L. Higano C. (2003) The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer [see comment]. J. Urol. 170, 1808 1811. (Pubitemid 37254933)
6. Cherrier M. M., Matsumoto A. M., Amory J. K., Ahmed S., Bremner W., Peskind E. R., Raskind M. A., Johnson M. Craft S. (2005) The role of aromatization in testosterone supplementation: effects on cognition in older men. Neurology 64, 290 296.
7. Clement Y., Calatayud F. Belzung C. (2002) Genetic basis of anxiety-like behaviour: a critical review. Brain Res. Bull. 57, 57 71. (Pubitemid 34097771)
8. Contarino A., Dellu F., Koob G. F., Smith G. W., Lee K. F., Vale W. Gold L. H. (1999) Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1. Brain Res. 835, 1 9. (Pubitemid 29336544)
9. Duva C. A., Floresco S. B., Wunderlich G. R., Lao T. L., Pinel J. P. Phillips A. G. (1997) Disruption of spatial but not object-recognition memory by neurotoxic lesions of the dorsal hippocampus in rats. Behav. Neurosci. 111, 1184 1196. (Pubitemid 28010896)
10. Ennaceur A. Aggleton J. P. (1997) The effects of neurotoxic lesions of the perirhinal cortex combined to fornix transection on object recognition memory in the rat. Behav. Brain Res. 88, 181 193. (Pubitemid 27498504)
11. Frye C. A. Lacey E. H. (2001) Posttraining androgens' enhancement of cognitive performance is temporally distinct from androgens' increases in affective behavior. Cogn. Affect. Behav. Neurosci. 1, 172 182. (Pubitemid 38392492)
12. Frye C. A. Seliga A. M. (2001) Testosterone increases analgesia, anxiolysis, and cognitive performance of male rats. Cogn. Affect. Behav. Neurosci. 1, 371 381. (Pubitemid 38391258)
13. Gibbs R. B. (2005) Testosterone and estradiol produce different effects on cognitive performance in male rats. Horm. Behav. 48, 268 277. (Pubitemid 41160533)
14. Gomez F., Manalo S., Dallman M. F., Gomez F., Manalo S. Dallman M. F. (2004) Androgen-sensitive changes in regulation of restraint-induced adrenocorticotropin secretion between early and late puberty in male rats. Endocrinology 145, 59 70. (Pubitemid 38094501)
15. Guzowski J. F. McGaugh J. L. (1997) Antisense oligodeoxynucleotide- mediated disruption of hippocampal cAMP response element binding protein levels impairs consolidation of memory for water maze training. Proc. Natl Acad. Sci. USA 94, 2693 2698. (Pubitemid 27136938)
16. Hebbard P. C., King R. R., Malsbury C. W. Harley C. W. (2003) Two organizational effects of pubertal testosterone in male rats: transient social memory and a shift away from long-term potentiation following a tetanus in hippocampal CA1. Exp. Neurol. 182, 470 475. (Pubitemid 36937100)
17. Janowsky J. S. (2006) The role of androgens in cognition and brain aging in men. Neuroscience 138, 1015 1020. (Pubitemid 43306842)
18. Janowsky J. S., Chavez B. Orwoll E. (2000) Sex steroids modify working memory. J. Cogn. Neurosci. 12, 407 414. (Pubitemid 30410281)
19. Kritzer M. F., McLaughlin P. J., Smirlis T. Robinson J. K. (2001) Gonadectomy impairs T-maze acquisition in adult male rats. Horm. Behav. 39, 167 174. (Pubitemid 32217592)
20. Mendez I. A., Montgomery K. S., LaSarge C. L., Simon N. W., Bizon J. L. Setlow B. (2008) Long-term effects of prior cocaine exposure on Morris water maze performance. Neurobiol. Learn. Mem. 89, 185 191. (Pubitemid 350235970)
21. Muller M. B., Zimmermann S., Sillaber I. et al. (2003) Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress [see comment]. Nat. Neurosci. 6, 1100 1107. (Pubitemid 37186203)
22. Pfankuch T., Rizk A., Olsen R., Poage C. Raber J. (2005) Role of circulating androgen levels in effects of apoE4 on cognitive function. Brain Res. 1053, 88 96. (Pubitemid 41116793)
23. Raber J. (2004) Androgens, apoE, and Alzheimer's disease. Sci. Aging Knowledge Environ. 2004, re2.
24. Raber J., Bongers G., LeFevour A., Buttini M. Mucke L. (2002) Androgens protect against apolipoprotein E4-induced cognitive deficits. J. Neurosci. 22, 5204 5209. (Pubitemid 37465633)
25. Salminen E., Portin R., Korpela J., Backman H., Parvinen L. M., Helenius H. Nurmi M. (2003) Androgen deprivation and cognition in prostate cancer. Br. J. Cancer 89, 971 976. (Pubitemid 37239197)
26. Sandstrom N. J., Kim J. H. Wasserman M. A. (2006) Testosterone modulates performance on a spatial working memory task in male rats. Horm. Behav. 50, 18 26. (Pubitemid 43776835)
27. Schafe G. E., Atkins C. M., Swank M. W., Bauer E. P., Sweatt J. D. LeDoux J. E. (2000) Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning. J. Neurosci. 20, 8177 8187. (Pubitemid 30804670)
28. Spritzer M. D., Gill M., Weinberg A. Galea L. A. (2007) Castration differentially affects spatial working and reference memory in male rats. Arch. Sex. Behav. 37, 19 29.
29. Stough S., Shobe J. L. Carew T. J. (2006) Intermediate-term processes in memory formation. Curr. Opin. Neurobiol. 16, 672 678. (Pubitemid 44791929)
30. Swartzwelder H. S. (1981) Deficits in passive avoidance and fear behavior following bilateral and unilateral amygdala lesions in mice. Physiol. Behav. 26, 323 326. (Pubitemid 11147339)
31. Viau V., Soriano L. Dallman M. (2001) Androgens alter corticotropin releasing hormone and arginine vasopressin mRNA within forebrain sites known to regulate activity in the hypothalamic-pituitary-adrenal axis. J. Neuroendocrinol. 13, 442 452. (Pubitemid 32377560)
32. van Wimersma Greidanus T. B., Burbach J. P. Veldhuis H. D. (1986) Vasopressin and oxytocin. Their presence in the central nervous system and their functional significance in brain processes related to behaviour and memory. Acta Endocrinol. Suppl. (Copenh) 276, 85 94. (Pubitemid 16010541)