Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1

Journal of Virology

Volumn 83, Issue 14, 2009, Pages 7194-7201

  Tian, Wang ^a   Hwang, Ying T ^a   Lu, Qiangsheng ^a   Hwang, Charles B C ^a  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; EXONUCLEASE; POL PROTEIN;

ARTICLE; DNA REPLICATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME KINETICS; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; HERPES SIMPLEX VIRUS 1; MUTAGENICITY; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MOTIF; VIROGENESIS; VIRUS RECOMBINANT; VIRUS REPLICATION; VIRUS SURVIVAL;

AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; EXODEOXYRIBONUCLEASES; HERPESVIRUS 1, HUMAN; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; VERO CELLS; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 67650424326     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00632-09     Document Type: Article

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