메뉴 건너뛰기




Volumn 2, Issue 5-6, 2009, Pages 295-305

Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; RETINAL DEHYDROGENASE; ALDEHYDE OXIDASE; HOMEODOMAIN PROTEIN; RALDH2 PROTEIN, XENOPUS; RETINOIC ACID; XENOPUS PROTEIN;

EID: 67650333184     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.001420     Document Type: Article
Times cited : (75)

References (61)
  • 1
    • 0000090925 scopus 로고    scopus 로고
    • Retinoic acid biosynthetic enzyme ALDH1 localizes in a subset of retinoid-dependent tissues during xenopus development
    • Ang, H. L. and Duester, G. (1999a). Retinoic acid biosynthetic enzyme ALDH1 localizes in a subset of retinoid-dependent tissues during xenopus development. Dev. Dyn. 215, 264-272.
    • (1999) Dev. Dyn. , vol.215 , pp. 264-272
    • Ang, H.L.1    Duester, G.2
  • 2
    • 0033558125 scopus 로고    scopus 로고
    • Stimulation of premature retinoic acid synthesis in Xenopus embryos following premature expression of aldehyde dehydrogenase ALDH1
    • Ang, H. L. and Duester, G. (1999b). Stimulation of premature retinoic acid synthesis in Xenopus embryos following premature expression of aldehyde dehydrogenase ALDH1. Eur. J. Biochem. 260, 227-234.
    • (1999) Eur. J. Biochem. , vol.260 , pp. 227-234
    • Ang, H.L.1    Duester, G.2
  • 3
    • 0034850924 scopus 로고    scopus 로고
    • The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain
    • Begemann, G., Schilling, T. F., Rauch, G. J., Geisler, R. and Ingham, P. W. (2001). The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development 128, 3081-3094. (Pubitemid 32825753)
    • (2001) Development , vol.128 , Issue.16 , pp. 3081-3094
    • Begemann, G.1    Schilling, T.F.2    Rauch, G.-J.3    Geisler, R.4    Ingham, P.W.5
  • 4
    • 2942601239 scopus 로고    scopus 로고
    • Beyond the neckless phenotype: Influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain
    • DOI 10.1016/j.ydbio.2004.03.033, PII S0012160604002490
    • Begemann, G., Marx, M., Mebus, K., Meyer, A. and Bastmeyer, M. (2004). Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain. Dev. Biol. 271, 119-129. (Pubitemid 38757780)
    • (2004) Developmental Biology , vol.271 , Issue.1 , pp. 119-129
    • Begemann, G.1    Marx, M.2    Mebus, K.3    Meyer, A.4    Bastmeyer, M.5
  • 5
    • 0345020436 scopus 로고    scopus 로고
    • Ethanol impairs migration of the prechordal plate in the zebrafish embryo
    • DOI 10.1006/dbio.1998.8995
    • Blader, P. and Strahle, U. (1998). Ethanol impairs migration of the prechordal plate in the zebrafish embryo. Dev. Biol. 201, 185-201. (Pubitemid 28447213)
    • (1998) Developmental Biology , vol.201 , Issue.2 , pp. 185-201
    • Blader, P.1    Strahle, U.2
  • 6
    • 35349027768 scopus 로고    scopus 로고
    • Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation
    • DOI 10.1002/dvdy.21312
    • Cammas, L., Romand, R., Fraulob, V., Mura, C. and Dolle, P. (2007). Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation. Dev. Dyn. 236, 2899-2908. (Pubitemid 47613253)
    • (2007) Developmental Dynamics , vol.236 , Issue.10 , pp. 2899-2908
    • Cammas, L.1    Romand, R.2    Fraulob, V.3    Mura, C.4    Dolle, P.5
  • 7
    • 0033777205 scopus 로고    scopus 로고
    • Alcohol and the developing fetus-a review
    • Chaudhuri, J. D. (2000). Alcohol and the developing fetus-a review. Med. Sci. Monit. 6, 1031-1041.
    • (2000) Med. Sci. Monit. , vol.6 , pp. 1031-1041
    • Chaudhuri, J.D.1
  • 8
    • 0027058751 scopus 로고
    • Comparison of Hensen's node and retinoic acid in secondary axis induction in the early chick embryo
    • Chen, Y., Huang, L., Russo, A. F. and Solursh, M. (1992). Retinoic acid is enriched in Hensen's node and is developmentally regulated in the early chicken embryo. Proc. Natl. Acad. Sci. USA 89, 10056-10059. (Pubitemid 23088942)
    • (1992) Developmental Dynamics , vol.195 , Issue.2 , pp. 142-151
    • Chen, Y.1    Solursh, M.2
  • 9
    • 0028158930 scopus 로고
    • A concentration gradient of retinoids in the early Xenopus laevis embryo
    • DOI 10.1006/dbio.1994.1008
    • Chen, Y., Huang, L. and Solursh, M. (1994). A concentration gradient of retinoids in the early Xenopus laevis embryo. Dev. Biol. 161, 70-76. (Pubitemid 24049155)
    • (1994) Developmental Biology , vol.161 , Issue.1 , pp. 70-76
    • Chen, Y.1    Huang, L.2    Solursh, M.3
  • 10
    • 0035117914 scopus 로고    scopus 로고
    • Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos
    • DOI 10.1016/S0925-4773(00)00558-X, PII S092547730000558X
    • Chen, Y., Pollet, N., Niehrs, C. and Pieler, T. (2001). Increased XRALDH2 activity has a posteriorizing effect on the central nervous system of Xenopus embryos. Mech. Dev. 101, 91-103. (Pubitemid 32186313)
    • (2001) Mechanisms of Development , vol.101 , Issue.1-2 , pp. 91-103
    • Chen, Y.1    Pollet, N.2    Niehrs, C.3    Pieler, T.4
  • 11
    • 0026342562 scopus 로고
    • Molecular nature of Spemann's organizer: The role of the xenopus homeobox gene goosecoid
    • Cho, K. W. Y., Blumberg, B., Steinbeisser, H. and De Robertis, E. M. (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120. (Pubitemid 121001524)
    • (1991) Cell , vol.67 , Issue.6 , pp. 1111-1120
    • Cho, K.W.Y.1    Blumberg, B.2    Steinbeisser, H.3    De Robertis, E.M.4
  • 12
    • 0036029643 scopus 로고    scopus 로고
    • The role of vitamin a in mammalian reproduction and embryonic development
    • DOI 10.1146/annurev.nutr.22.010402.102745E
    • Clagett-Dame, M. and DeLuca, H. F. (2002). The role of vitamin A in mammalian reproduction and embryonic development. Annu. Rev. Nutr. 22, 347-381. (Pubitemid 35229924)
    • (2002) Annual Review of Nutrition , vol.22 , pp. 347-381
    • Clagett-Dame, M.1    Deluca, H.F.2
  • 13
    • 0000986921 scopus 로고
    • Excessive intake of vitamin A as a cause of congenital abnormalities in the rat
    • Cohlan, S. Q. (1953). Excessive intake of vitamin A as a cause of congenital abnormalities in the rat. Science 117, 535-536.
    • (1953) Science , vol.117 , pp. 535-536
    • Cohlan, S.Q.1
  • 14
    • 0026784387 scopus 로고
    • 4- Methylpyrazole partially ameliorated the teratogenicity of retinol and reduced the metabolic formation of all-trans-retinoic acid in the mouse
    • Collins, M. D., Eckhoff, C., Chahoud, I., Bochert, G. and Nau, H. (1992). 4- Methylpyrazole partially ameliorated the teratogenicity of retinol and reduced the metabolic formation of all-trans-retinoic acid in the mouse. Arch. Toxicol. 66, 652-659.
    • (1992) Arch. Toxicol. , vol.66 , pp. 652-659
    • Collins, M.D.1    Eckhoff, C.2    Chahoud, I.3    Bochert, G.4    Nau, H.5
  • 15
    • 0030021669 scopus 로고    scopus 로고
    • Endogenous retinoids in the zebrafish embryo and adult
    • DOI 10.1002/(SICI)1097-0177(199601)205:1<41::AID-AJA4>3.0.CO;2-5
    • Costaridis, P., Horton, C., Zeitlinger, J., Holder, N. and Maden, M. (1996). Endogenous retinoids in the zebrafish embryo and adult. Dev. Dyn. 205, 41-51. (Pubitemid 26005402)
    • (1996) Developmental Dynamics , vol.205 , Issue.1 , pp. 41-51
    • Costaridis, P.1    Horton, C.2    Zeitlinger, J.3    Holder, N.4    Maden, M.5
  • 16
    • 2142650784 scopus 로고    scopus 로고
    • Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology
    • DOI 10.1079/PNS2003327
    • Crabb, D. W., Matsumoto, M., Chang, D. and You, M. (2004). Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology. Proc. Nutr. Soc. 63, 49-63. (Pubitemid 38543873)
    • (2004) Proceedings of the Nutrition Society , vol.63 , Issue.1 , pp. 49-63
    • Crabb, D.W.1    Matsumoto, M.2    Chang, D.3    You, M.4
  • 17
    • 0028282623 scopus 로고
    • Temporal distribution, localization and metabolism of all-trans-retinol, didehydroretinol and all-trans-retinal during Xenopus development
    • Creech Kraft, J., Schuh, T., Juchau, M. R. and Kimelman, D. (1994). Temporal distribution, localization and metabolism of all-trans-retinol, didehydroretinol and all-trans-retinal during Xenopus development. Biochem. J. 301, 111-119. (Pubitemid 24214689)
    • (1994) Biochemical Journal , vol.301 , Issue.1 , pp. 111-119
    • Creech Kraft, J.1    Schuh, T.2    Juchau, M.R.3    Kimelman, D.4
  • 18
    • 0043166515 scopus 로고    scopus 로고
    • Retinoid receptors and vitamin a deficiency: Differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid
    • DOI 10.1016/S0012-1606(03)00257-4
    • Cui, J., Michaille, J. J., Jiang, W. and Zile, M. H. (2003). Retinoid receptors and vitamin A deficiency: differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid. Dev. Biol. 260, 496-511. (Pubitemid 36966085)
    • (2003) Developmental Biology , vol.260 , Issue.2 , pp. 496-511
    • Cui, J.1    Michaille, J.-J.2    Jiang, W.3    Zile, M.H.4
  • 19
    • 9444279057 scopus 로고    scopus 로고
    • Ethanol inhibition of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome
    • Deltour, L., Ang, H. L. and Duester, G. (1996). Ethanol inhibiton of retinoic acid synthesis as a potential mechanism for fetal alcohol syndrome. FASEB J. 10, 1050-1057. (Pubitemid 26285981)
    • (1996) FASEB Journal , vol.10 , Issue.9 , pp. 1050-1057
    • Deltour, L.1    Ang, H.L.2    Duester, G.3
  • 20
    • 1942421270 scopus 로고    scopus 로고
    • Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo
    • DOI 10.1016/j.mod.2004.02.008, PII S092547730400036X
    • Dobbs-McAuliffe, B., Zhao, Q. and Linney, E. (2004). Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo. Mech. Dev. 121, 339-350. (Pubitemid 38510590)
    • (2004) Mechanisms of Development , vol.121 , Issue.4 , pp. 339-350
    • Dobbs-McAuliffe, B.1    Zhao, Q.2    Linney, E.3
  • 21
    • 0025733960 scopus 로고
    • A hypothetical mechanism for fetal alcohol syndrome involving ethanol inhibition of retinoic acid synthesis at the alcohol dehydrogenase step
    • Duester, G. (1991). A hypothetical mechanism for fetal alcohol syndrome involving ethanol inhibition of retinoic acid synthesis at the alcohol dehydrogenase step. Alcohol. Clin. Exp. Res. 15, 568-572.
    • (1991) Alcohol. Clin. Exp. Res. , vol.15 , pp. 568-572
    • Duester, G.1
  • 22
    • 0029778148 scopus 로고    scopus 로고
    • Involvement of alcohol dehydrogenase, short-chain dehydrogenase/ reductase, aldehyde dehydrogenase, and cytochromo P450 in the control of retinoid signaling by activation of retinoic acid synthesis
    • Duester, G. (1996). Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochromo P450 in the control of retinoid signaling by activation of retinoic acid synthesis. Biochemistry 35, 12221-12227.
    • (1996) Biochemistry , vol.35 , pp. 12221-12227
    • Duester, G.1
  • 23
    • 0033911401 scopus 로고    scopus 로고
    • Families of retinoid dehydrogenases regulating vitamin A function: Production of visual pigment and retinoic acid
    • Duester, G. (2000). Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid. Eur. J. Biochem. 267, 4315-4324.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 4315-4324
    • Duester, G.1
  • 24
    • 0024362874 scopus 로고
    • Retinoic acid causes an anteroposterior transformation in the developing central nervous system
    • DOI 10.1038/340140a0
    • Durston, A. J., Timmermans, J. P. M., Hage, W. J., Hendriks, H. F. J., de Vries, N. J., Heideveld, M. and Nieuwkoop, P. D. (1989). Retinoic acid causes an anteroposterior transformation in the developing central nervous system. Nature 340, 140-144. (Pubitemid 19175364)
    • (1989) Nature , vol.340 , Issue.6229 , pp. 140-144
    • Durston, A.J.1    Timmermans, J.P.M.2    Hage, W.J.3    Hendriks, H.F.J.4    De Vries, N.J.5    Heideveld, M.6    Nieuwkoop, P.D.7
  • 25
    • 0030840280 scopus 로고    scopus 로고
    • Patterning of the embryo along the anterior-posterior axis: The role of the caudal genes
    • Epstein, M., Pillemer, G., Yelin, R., Yisraeli, J. K. and Fainsod, A. (1997). Patterning of the embryo along the anterior-posterior axis: the role of the caudal genes. Development 124, 3805-3814. (Pubitemid 27482977)
    • (1997) Development , vol.124 , Issue.19 , pp. 3805-3814
    • Epstein, M.1    Pillemer, G.2    Yelin, R.3    Yisraeli, J.K.4    Fainsod, A.5
  • 27
    • 0031469373 scopus 로고    scopus 로고
    • Formation and function of Spemann's organizer
    • Harland, R. and Gerhart, J. (1997). Formation and function of Spemann's organizer. Annu. Rev. Cell Dev. Biol. 13, 611-667.
    • (1997) Annu. Rev. Cell Dev. Biol. , vol.13 , pp. 611-667
    • Harland, R.1    Gerhart, J.2
  • 28
    • 0032713404 scopus 로고    scopus 로고
    • Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways
    • Haselbeck, R. J., Hoffmann, I. and Duester, G. (1999). Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways. Dev. Genet. 25, 353-364.
    • (1999) Dev. Genet. , vol.25 , pp. 353-364
    • Haselbeck, R.J.1    Hoffmann, I.2    Duester, G.3
  • 29
    • 0037086052 scopus 로고    scopus 로고
    • Morpholino oligos: Making sense of antisense?
    • Heasman, J. (2002). Morpholino oligos: making sense of antisense? Dev. Biol. 243, 209-214.
    • (2002) Dev. Biol. , vol.243 , pp. 209-214
    • Heasman, J.1
  • 30
    • 0025187556 scopus 로고
    • Localization of specific mRNAs in Xenopus embryos by whole-mount in situ hybridization
    • Hemmati-Brivanlou, A., Frank, D., Bolce, M. E., Brown, B. D., Sive, H. L. and Harland, R. M. (1990). Localization of specific mRNAs in Xenopus embryos by wholemount in situ hybridization. Development 110, 325-330. (Pubitemid 20330508)
    • (1990) Development , vol.110 , Issue.2 , pp. 325-330
    • Hemmati-Brivanlou, A.1    Frank, D.2    Bolce, M.E.3    Brown, B.D.4    Sive, H.L.5    Harland, R.M.6
  • 31
    • 0024469507 scopus 로고
    • Arrest of epidermal growth factor-dependent growth in fetal hepatocytes after ethanol exposure
    • Henderson, G. I., Baskin, G. S., Horbach, J., Porter, P. and Schenker, S. (1989). Arrest of epidermal growth factor-dependent growth in fetal hepatocytes after ethanol exposure. J. Clin. Invest. 84, 1287-1294. (Pubitemid 19247602)
    • (1989) Journal of Clinical Investigation , vol.84 , Issue.4 , pp. 1287-1294
    • Henderson, G.I.1    Baskin, G.S.2    Horbach, J.3    Porter, P.4    Schenker, S.5
  • 32
    • 0031766890 scopus 로고    scopus 로고
    • Alcohol dehydrogenases in Xenopus development: Conserved expression of ADG1 and ADH4 in epithelial retinoid target tissues
    • DOI 10.1002/(SICI)1097-0177(199811)213:3<261::AID-AJA3>3.0.CO;2-V
    • Hoffmann, I., Ang, H. L. and Duester, G. (1998). Alcohol dehydrogenases in Xenopus development: conserved expression of ADH1 and ADH4 in epithelial retinoid target tissues. Dev. Dyn. 213, 261-270. (Pubitemid 28507232)
    • (1998) Developmental Dynamics , vol.213 , Issue.3 , pp. 261-270
    • Hoffmann, I.1    Ang, H.L.2    Duester, G.3
  • 33
    • 0026783379 scopus 로고
    • Evidence that Hensen's node is a site of retinoic acid synthesis
    • Hogan, L. M., Thaller, C. and Eichele, G. (1992). Evidence that Hensen's node is a site of retinoic acid synthesis. Nature 359, 237-241.
    • (1992) Nature , vol.359 , pp. 237-241
    • Hogan, L.M.1    Thaller, C.2    Eichele, G.3
  • 34
    • 0032535144 scopus 로고    scopus 로고
    • Regionalized metabolic activity establishes boundaries of retinoic acid signalling
    • DOI 10.1093/emboj/17.24.7361
    • Hollemann, T., Chen, Y., Grunz, H. and Pieler, T. (1998). Regionalized metabolic activity establishes boundaries of retinoic acid signalling. EMBO J. 17, 7361-7372. (Pubitemid 29002704)
    • (1998) EMBO Journal , vol.17 , Issue.24 , pp. 7361-7372
    • Hollemann, T.1    Chen, Y.2    Grunz, H.3    Pieler, T.4
  • 35
    • 0037083266 scopus 로고    scopus 로고
    • Moderate alcohol intake during pregnancy and the risk of stillbirth and death in the first year of life
    • DOI 10.1093/aje/155.4.305
    • Kesmodel, U., Wisborg, K., Olsen, S. F., Henriksen, T. B. and Secher, N. J. (2002a). Moderate alcohol intake during pregnancy and the risk of stillbirth and death in the first year of life. Am. J. Epidemiol. 155, 305-312. (Pubitemid 34132048)
    • (2002) American Journal of Epidemiology , vol.155 , Issue.4 , pp. 305-312
    • Kesmodel, U.1    Wisborg, K.2    Olsen, S.F.3    Henriksen, T.B.4    Secher, N.J.5
  • 36
    • 0036177327 scopus 로고    scopus 로고
    • Moderate alcohol intake in pregnancy and the risk of spontaneous abortion
    • Kesmodel, U., Wisborg, K., Olsen, S. F., Henriksen, T. B. and Secher, N. J. (2002b). Moderate alcohol intake in pregnancy and the risk of spontaneous abortion. Alcohol Alcohol. 37, 87-92. (Pubitemid 34173315)
    • (2002) Alcohol and Alcoholism , vol.37 , Issue.1 , pp. 87-92
    • Kesmodel, U.1    Wisborg, K.2    Olsen, S.F.3    Henriksen, T.B.4    Secher, N.J.5
  • 37
    • 0026772226 scopus 로고
    • Respecification of vertebral identities by retinoic acid
    • Kessel, M. (1992). Respecification of vertebral identities by retinoic acid. Development 115, 487-501.
    • (1992) Development , vol.115 , pp. 487-501
    • Kessel, M.1
  • 38
    • 0345376187 scopus 로고    scopus 로고
    • Fetal alcohol spectrum disorder
    • Koren, G., Nulman, I., Chudley, A. E. and Loocke, C. (2003). Fetal alcohol spectrum disorder. CMAJ 169, 1181-1185.
    • (2003) CMAJ , vol.169 , pp. 1181-1185
    • Koren, G.1    Nulman, I.2    Chudley, A.E.3    Loocke, C.4
  • 39
    • 0028846081 scopus 로고
    • Ethanol-induced teratogenesis: Free radical damage as a possible mechanism
    • Kotch, L. E., Chen, S. Y. and Sulik, K. K. (1995). Ethanol-induced teratogenesis: free radical damage as a possible mechanism. Teratology 52, 128-136.
    • (1995) Teratology , vol.52 , pp. 128-136
    • Kotch, L.E.1    Chen, S.Y.2    Sulik, K.K.3
  • 40
    • 0031043536 scopus 로고    scopus 로고
    • A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate
    • Li, H., Tierney, C., Wen, L., Wu, J. Y. and Rao, Y. (1997). A single morphogenetic field gives rise to two retina primordia under the influence of the prechordal plate. Development 124, 603-615. (Pubitemid 27092426)
    • (1997) Development , vol.124 , Issue.3 , pp. 603-615
    • Li, H.-S.1    Tierney, C.2    Wen, L.3    Wu, J.Y.4    Rao, Y.5
  • 41
    • 0035710746 scopus 로고    scopus 로고
    • -δδCT method
    • DOI 10.1006/meth.2001.1262
    • Livak, K. J. and Schmittgen, T. D. (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 42
    • 0030113685 scopus 로고    scopus 로고
    • Vitamin A-deficient quail embryos have half a hindbrain and other neural defects
    • Maden, M., Gale, E., Kostetskii, I. and Zile, M. (1996). Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Curr. Biol. 6, 417-426. (Pubitemid 126656289)
    • (1996) Current Biology , vol.6 , Issue.4 , pp. 417-426
    • Maden, M.1    Gale, E.2    Kostetskii, I.3    Zile, M.4
  • 43
    • 0037303259 scopus 로고    scopus 로고
    • Retinoic acid metabolism and mechanism of action: A review
    • DOI 10.2174/1389200033336900
    • Marill, J., Idres, N., Capron, C. C., Nguyen, E. and Chabot, G. G. (2003). Retinoic acid metabolism and mechanism of action: a review. Curr. Drug Metab. 4, 1-10. (Pubitemid 36131681)
    • (2003) Current Drug Metabolism , vol.4 , Issue.1 , pp. 1-10
    • Marill, J.1    Idres, N.2    Capron, C.C.3    Nguyen, E.4    Chabot, G.5
  • 44
    • 0021021470 scopus 로고
    • Craniofacial malformation in Xenopus laevis tadpoles caused by the exposure of early embryos to ethanol
    • Nakatsuji, N. (1983). Craniofacial malformation in Xenopus laevis tadpoles caused by the exposure of early embryos to ethanol. Teratology 28, 299-305.
    • (1983) Teratology , vol.28 , pp. 299-305
    • Nakatsuji, N.1
  • 45
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse post- Implantation development
    • DOI 10.1038/7788
    • Niederreither, K., Subbarayan, V., Dolle, P. and Chambon, P. (1999). Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 21, 444-448. (Pubitemid 29159586)
    • (1999) Nature Genetics , vol.21 , Issue.4 , pp. 444-448
    • Niederreither, K.1    Subbarayan, V.2    Dolle, P.3    Chambon, P.4
  • 48
    • 0025799778 scopus 로고
    • Hypothesis: Prenatal ethanol-induced birth defects and retinoic acid
    • Pullarkat, R. K. (1991). Hypothesis: prenatal ethanol-induced birth defects and retinoic acid. Alcohol Clin. Exp. Res. 15, 565-567.
    • (1991) Alcohol Clin. Exp. Res. , vol.15 , pp. 565-567
    • Pullarkat, R.K.1
  • 49
    • 0026055409 scopus 로고
    • Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis
    • Rossant, J., Zirngibl, R., Cado, D., Shago, M. and Giguère, V. (1991). Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev. 5, 1333-1344. (Pubitemid 21906042)
    • (1991) Genes and Development , vol.5 , Issue.8 , pp. 1333-1344
    • Rossant, J.1    Zirngibl, R.2    Cado, D.3    Shago, M.4    Giguere, V.5
  • 50
    • 0023937876 scopus 로고
    • Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde
    • DOI 10.1016/0006-2952(88)90030-5
    • Russo, J. E., Hauguitz, D. and Hilton, J. (1988). Inhibition of mouse cytosolic aldehyde dehydrogenase by 4-(diethylamino)benzaldehyde. Biochem. Pharmacol. 37, 1639-1642. (Pubitemid 18093362)
    • (1988) Biochemical Pharmacology , vol.37 , Issue.8 , pp. 1639-1642
    • Russo, J.E.1    Hauquitz, D.2    Hilton, J.3
  • 51
    • 0035862976 scopus 로고    scopus 로고
    • The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo
    • DOI 10.1101/gad.851501
    • Sakai, Y., Meno, C., Fujii, H., Nishino, J., Shiratori, H., Saijoh, Y., Rossant, J. and Hamada, H. (2001). The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev. 15, 213-225. (Pubitemid 32107666)
    • (2001) Genes and Development , vol.15 , Issue.2 , pp. 213-225
    • Sakai, Y.1    Meno, C.2    Fujii, H.3    Nishino, J.4    Shiratori, H.5    Saijoh, Y.6    Rossant, J.7    Hamada, H.8
  • 53
    • 0027967380 scopus 로고
    • Xenopus chordin: A novel dorsalizing factor activated by organizer- Specific homeobox genes
    • DOI 10.1016/0092-8674(94)90068-X
    • Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M. (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790. (Pubitemid 24371969)
    • (1994) Cell , vol.79 , Issue.5 , pp. 779-790
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    Geissert, D.4    Gont, L.K.5    De Robertis, E.M.6
  • 55
    • 0027466005 scopus 로고
    • Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm
    • DOI 10.1038/361547a0
    • Smith, W. C., Knecht, A. K., Wu, M. and Harland, R. M. (1993). Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature 361, 547-549. (Pubitemid 23055618)
    • (1993) Nature , vol.361 , Issue.6412 , pp. 547-549
    • Smith, W.C.1    Knecht, A.K.2    Wu, M.3    Harland, R.M.4
  • 56
    • 0345600948 scopus 로고    scopus 로고
    • Fetal alcohol spectrum disorder
    • Sokol, R. J., Delaney-Black, V. and Nordstrom, B. (2003). Fetal alcohol spectrum disorder. JAMA 290, 2996-2999.
    • (2003) JAMA , vol.290 , pp. 2996-2999
    • Sokol, R.J.1    Delaney-Black, V.2    Nordstrom, B.3
  • 58
    • 84958699162 scopus 로고
    • An analysis of the syndrome of malformations induced by maternal vitamin A deficeincy. Effects of restoration of vitamin A at various times during gestation
    • Wilson, J. G., Roth, C. B. and Warkany, J. (1953). An analysis of the syndrome of malformations induced by maternal vitamin A deficeincy. Effects of restoration of vitamin A at various times during gestation. Am. J. Anat. 92, 189-217.
    • (1953) Am. J. Anat. , vol.92 , pp. 189-217
    • Wilson, J.G.1    Roth, C.B.2    Warkany, J.3
  • 59
    • 13544267571 scopus 로고    scopus 로고
    • Ethanol exposure affects gene expression in the embryonic organizer and reduces retinoic acid levels
    • DOI 10.1016/j.ydbio.2004.12.014
    • Yelin, R., Ben-Haroush Schyr, R., Kot, H., Zins, S., Frumkin, A., Pillemer, G. and Fainsod, A. (2005). Ethanol exposure affects gene expression in the embryonic organizer and reduces retinoic acid levels. Dev. Biol. 279, 193-204. (Pubitemid 40222179)
    • (2005) Developmental Biology , vol.279 , Issue.1 , pp. 193-204
    • Yelin, R.1    Schyr, R.B.-H.2    Kot, H.3    Zins, S.4    Frumkin, A.5    Pillemer, G.6    Fainsod, A.7
  • 60
    • 34249033937 scopus 로고    scopus 로고
    • Early molecular effects of ethanol during vertebrate embryogenesis
    • DOI 10.1111/j.1432-0436.2006.00147.x
    • Yelin, R., Kot, H., Yelin, D. and Fainsod, A. (2007). Early molecular effects of ethanol during vertebrate embryogenesis. Differentiation 75, 393-403. (Pubitemid 46802151)
    • (2007) Differentiation , vol.75 , Issue.5 , pp. 393-403
    • Yelin, R.1    Kot, H.2    Yelin, D.3    Fainsod, A.4
  • 61
    • 0035095989 scopus 로고    scopus 로고
    • Function of vitamin A in vertebrate embryonic development
    • Zile, M. H. (2001). Function of vitamin A in vertebrate embryonic development. J. Nutr. 131, 705-708.
    • (2001) J. Nutr. , vol.131 , pp. 705-708
    • Zile, M.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.