Alcohol dehydrogenases in Xenopus development: Conserved expression of ADG1 and ADH4 in epithelial retinoid target tissues

Developmental Dynamics

Volumn 213, Issue 3, 1998, Pages 261-270

  Hoffmann, Ines ^a   Ang, Hwee Luan ^a   Duester, Gregg ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

Alcohol dehydrogenase; Class IADH; Class IV ADH; Embryogenesis; Esophagus; Intestine; Liver; Pronephros; Retinol dehydrogenase; Skin; Stomach; Xenopus

Indexed keywords

ALCOHOL DEHYDROGENASE; RETINOID; RETINOL DEHYDROGENASE;

ANIMAL CELL; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ANALYSIS; ENZYME SYNTHESIS; GENE EXPRESSION; IN SITU HYBRIDIZATION; MESONEPHROS; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; XENOPUS;

ALCOHOL DEHYDROGENASE; ALCOHOL OXIDOREDUCTASES; ANIMALS; EPITHELIUM; ESOPHAGUS; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; IN SITU HYBRIDIZATION; INTESTINES; LIVER; MAMMALS; MICE; MOLECULAR SEQUENCE DATA; PHYLOGENY; RNA, MESSENGER; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SKIN; STOMACH; TRETINOIN; XENOPUS;

EID: 0031766890     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199811)213:3<261::AID-AJA3>3.0.CO;2-V     Document Type: Article

References (63)

1. Ang HL, Duester G. Initiation of retinoid signaling in primitive streak mouse embryos: Spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis. Dev. Dyn. 1997;208:536-543.
2. Ang HL, Deltour L, Hayamizu TF, Zgombic-Knight M, Duester G. Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression. J. Biol. Chem. 1996a;271:9526-9534.
3. Ang HL, Deltour L, Zgombic-Knight M, Wagner MA, Duester G. Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis. Alcohol. Clin. Exp. Res. 1996b;20:1050-1064.
4. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K. Current Protocols in Molecular Biology, vol 2. New York: John Wiley & Sons, 1989.
5. Blumberg B, Bolado J Jr, Derguini F, Craig AG, Moreno TA, Chakravarti D, Heyman RA, Buck J, Evans RM. Novel retinoic acid receptor ligands in Xenopus embryos. Proc. Natl. Acad. Sci. USA 1996;93: 4873-4878.
6. Boleda MD, Saubi N, Farrés J, Parés X. Physiological substrates for rat alcohol dehydrogenase classes: Aldehydes of lipid peroxidation, omega-hydroxyfatty acids, and retinoids. Arch. Biochem. Biophys. 1993;307:85-90.
7. Cederlund E, Peralba JM, Parés X, Jörnvall H. Amphibian alcohol dehydrogenase, the major frog liver enzyme. Relationships to other forms and assessment of an early gene duplication separating vertebrate class I and class III alcohol dehydrogenases. Biochemistry 1991;30:2811-2816.
8. Chai X, Boerman MHEM, Zhai Y, Napoli JL. Cloning of a cDNA for liver microsomal retinol dehydrogenase. A tissue-specific, short-chain alcohol dehydrogenase. J. Biol. Chem. 1995a;270:3900-3904.
9. Chai X, Zhai Y, Popescu G, Napoli JL. Cloning of a cDNA for a second retinol dehydrogenase type II-Expression of its mRNA relative to type I. J. Biol. Chem. 1995b;270:28408-28412.
10. Chai X, Zhai Y, Napoli JL. Cloning of a rat cDNA encoding retinol dehydrogenase isozyme type III. Gene 1996;169:219-222.
11. Chen Y, Huang L, Solursh M. A concentration gradient of retinoids in the early Xenopus laevis embryo. Dev. Biol. 1994;161:70-76.
12. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987;162:156-159.
13. Connor MJ, Smit MH. Terminal-group oxidation of retinol by mouse epidermis: Inhibition in vitro and in vivo. Biochem. J. 1987;244:489-492.
14. Creech Kraft J, Schuh T, Juchau M, Kimelman D. The retinoid X receptor ligand, 9-cis-retinoic acid, is a potential regulator of early Xenopus development. Proc. Natl. Acad. Sci. USA 1994a;91:3067-3071.
15. Creech Kraft J, Schuh T, Juchau MR, Kimelman D. Temporal distribution, localization and metabolism of all-trans-retinol. didehydroretinol and all-trans-retinal during Xenopus development. Biochem. J. 1994b;301:111-119.
16. Danielsson O, Eklund H, Jörnvall H. The major piscine liver alcohol dehydrogenase has class-mixed properties in relation to mammalian alcohol dehydrogenases of classes I and III. Biochemistry 1992;31:3751-3759.
17. Danielsson O, Atrain S, Luque T, Hjelmqvist L, Gonzàlez-Duarte R, Jörnvall H. Fundamental molecular differences between alcohol dehydrogenase classes. Proc. Natl. Acad. Sci. USA 1994;91:4980-4984.
18. De Luca L, Little EP, Wolf G. Vitamin A and protein synthesis by rat intestinal mucosa. J. Biol. Chem. 1969;244:701-708.
19. De Luca L, Schumacher M, Wolf, G. Biosynthesis of a fucosecontaining glycopeptide from rat small intestine in normal and vitamin A-deficient conditions. J. Biol. Chem. 1970;245:4551-4558.
20. Duester G. Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis. Biochemistry 1996;35:12221-12227.
21. Duester G, Deltour L, Ang HL. Evidence that class IV alcohol dehydrogenase may function in embryonic retinoic acid synthesis. Adv. Exp. Med. Biol. 1997;414:357-364.
22. Durston AJ, Timmermans JPM, Hage WJ, Hendriks HFJ, De Vries NJ, Heideveld M, Nieuwkoop PD. Retinoic acid causes an anteroposterior transformation in the developing central nervous system. Nature 1989;340:140-144.
23. Fisher GJ, Voorhees JJ. Molecular mechanisms of retinoid actions in skin. FASEB J. 1996;10:1002-1013.
24. Frazier CN, Hu CK. Cutaneous lesions associated with a deficiency in vitamin A in man. Arch Intern. Med. 1931;48:507-514.
25. Gudas LJ, Sporn MB, Roberts AB. Cellular biology and biochemistry of the retinoids. In: Sporn MB, Roberts AB, Goodman DS, eds. The Retinoids: Biology, Chemistry, and Medicine. 2nd ed. New York: Raven Press, 1994:443-520.
26. Harland RM. In situ hybridization: An improved whole-mount method for Xenopus embryos. In: Kay BK, Peng HB, eds. Methods in Cell Biology, vol. 36. Xenopus laevis: Practical Uses in Cell and Molecular Biology. San Diego: Academic Press 1991:685-695.
27. Haselbeck RJ, Duester G. Regional restriction of alcohol/retinol dehydrogenases along the mouse gastrointestinal epithelium. Alcohol. Clin. Exp. Res. 1997;21.1484-1490.
28. Haselbeck RJ, Ang HL, Deltour L, Duester G. Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: A potential endocrine source of retinoic acid during development. Endocrinology 1997a;138:3035-3041.
29. Haselbeck RJ, Ang HL, Duester G. Class IV alcohol/retinol dehydrogenase localization in epidermal basal layer: Potential site of retinoic acid synthesis during skin development. Dev. Dyn. 1997b;208:447-453.
30. Hofmann C, Eichele G. Retinoids in development in Sporn MB, Roberts AB, Goodman DS, eds. The Retinoids: Biology, Chemistry, and Medicine. 2nd ed. New York: Raven Press, 1994:387-441.
31. Jörnvall H, Danielsson O, Hjelmqvist L, Persson B, Shafqat J. The alcohol dehydrogenase system. Adv. Exp. Med. Biol. 1995;372:281-294.
32. Kastner P, Chambon P, Leid M. Role of nuclear retinoic acid receptors in the regulation of gene expression. In: Blomhoff, R, ed. Vitamin A in Health and Disease. New York: Marcel Dekker, 1994:189-238.
33. Kaufman MH. The Atlas of Mouse Development. San Diego: Academic Press 1992.
34. Kedishvili, NY, Bosron WF, Stone CL, Hurley TD, Peggs CF, Thomasson HR, Popov KM, Carr LG, Edenberg HJ, Li T-K. Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase. Active-site amino acid sequence explains substrate specificity compared with liver isozymes. J. Biol. Chem. 1995;270: 3625-3630.
35. Kedishvili NY, Gough WH, Chernoff EAG, Hurley TD, Stone CL, Bowman KD, Popov KM, Bosron WF, Li TK. cDNA sequence and catalytic properties of a chick embryo alcohol dehydrogenase that oxidizes retinol and 3β,5α-hydroxysteroids. J. Biol. Chem. 1997;272: 7494-7500.
36. Klein-Szanto A, Martin D, Pine A. Cutaneous manifestations in rats with advanced vitamin A deficiency. J. Cutan. Pathol. 1980;7:260-270.
37. Kraft JC, Kimelman D, Juchau MR. Xenopus laevis: A model system for the study of embryonic retinoid metabolism: I. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols to their corresponding acid forms. Drug Metab. Dispos. 1995;23:72-82.
38. Lohnes D, Mark M, Mendelsohn C, Dollé P, Dierich A, Gorry P, Gansmuller A, Chambon P. Function of the retinoic acid receptors (RARs) during development. (I) Craniofacial and skeletal abnormalities in RAR double mutants. Development 1994;120:2723-2748.
39. Luo JM, Sucov HM, Bader JA, Evans RM, Giguère V. Compound mutants for retinoic acid receptor (RAR) β and RARα1 reveal development functions for multiple RARβ isoforms. Mech. Dev. 1996;55:33-44.
40. Luque T, Atrian S, Danielsson O, Jörnvall H, Gonzàlez-Duarte R. Structure of the Drosphila melanogaster glutathione-dependent formaldehyde dehyrdogenase/octanol dehydrogenase gene (class III alcohol dehydrogenase) - Evolutionary pathway of the alcohol dehydrogenase genes. Eur. J. Biochem. 1994;225:985-993.
41. Mak KM, Leo MA, Lieber CS. Effect of ethanol and vitamin A deficiency on epithelial cell proliferation and structure in the rat esophagus. Gastroenterology 1987;93:362-370.
42. Mangelsdorf DJ, Umesono K, Evans RM. The retinoid receptors. In: Sporn MB, Roberts AB, Goodman DS, eds. The Retinoids: Biology, Chemistry, and Medicine. 2nd ed. New York: Raven Press, 1994:319-349.
43. Mendelsohn C, Lohnes D, Décimo D, Lufkin T, LeMeur M, Chambon P, Mark M. Function of the retinoic acid receptors (RARs) during development. (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 1994;120:2749-2771.
44. Moreno A, Farrés J, Parés X, Jörnvall H, Persson B. Molecular modelling of human gastric alcohol dehydrogenase (class IV) and substrate docking: Differences towards the classical liver enzyme (class I). FEBS Lett. 1996;395:99-102.
45. Nieuwkoop PD, Faber J. Normal Table of Xenopus Laevis (Daudin). New York: Garland Publishing 1994.
46. Parés X, Cederlund E, Moreno A, Hjelmqvist L, Farrés J, Jörnvall H. Mammalian class IV alcohol dehydrogenase (stomach alcohol dehydrogenase): Structure, origin, and correlation with enzymology. Proc. Natl. Acad. Sci. USA 1994;91:1893-1897.
47. Rosenthal D, Lancillotti F, Darwiche N, Sinha R, De Luca LM. Regulation of epithelial differentiation by retinoids. In: Blomhoff R, ed. Vitamin A in Health and Disease. New York: Marcel Dekker, 1994:425-450.
48. Sambrook J, Fritsch EF, Maniatis T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory 1989.
49. Schuh TJ, Hall BL, Creech Kraft J, Privalsky ML, Kimelman D. (1993) v-erbA and citral reduce the teratogenic effects of all-trans retinoic acid and retinol, respectively, in Xenopus embryogenesis. Development 1993;119:785-798.
50. Sharpe CR, Goldstone K. Retinoid receptors promote primary neurogenesis in Xenopus Development 1997;124:515-523.
51. Sive HL, Draper BW, Harland RM, Weintraub H. Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis. Genes Dev. 1990;4:932-942.
52. Smith JC. Purifying and assaying mesoderm-inducing factors from vertebrate embryos. In: Hartley DA, ed. Cellular Interactions in Development - A Practical Approach. Oxford: Oxford University Press, 1993:181-204.
53. Vallee BL, Bazzone TJ. Isozymes of human liver alcohol dehydrogenase. Curr. Top. Biol. Med. Res. 1983;8:219-244.
54. Wesolowski MH, Lyerla TA. The developmental appearance of hexokinase and alcohol dehydrogenase in Xenopus laevis. J. Exp. Zool. 1979;210:211-220.
55. solowski MH, Lyerla TA. Alcohol dehydrogenase isozymes in the clawed frog, Xenopus laevis. Biochem. Genet. 1983;21:1003-1017.
56. Whitmire D, Bowen JP, Shim JY, Whitmire PS. Computational modeling of a putative fetal alcohol syndrome mechanism. Alcohol Clin. Exp. Res. 1995;19:1587-1593.
57. Wilson JG, Roth CB, Warkany J. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am. J. Anat. 1953;92:189-217.
58. Wolbach SB, Howe PR. Tissue changes following deprivation of fat-soluble A vitamin. J. Exp. Med. 1925;42:753-777.
59. Xie PG, Parsons SH, Speckhard DC, Bosron WF, Hurley TD. X-ray structure of human class IV σσalcohol dehydrogenase - Structural basis for substrate specificity. J. Biol. Chem. 1997;272:18558-18563.
60. Yang Z-N, Davis GJ, Hurley TD, Stone CL, Li T-K, Bosron WF. Catalytic efficiency of human alcohol dehydrogenases for retinol oxidation and retinal reduction. Alcohol Clin. Exp. Res. 1994;18:587-591.
61. Zgombic-Knight M, Ang HL, Foglio MH, Duester G. Cloning of the mouse class IV alcohol dehydrogenase (reginol dehydrogenase) cDNA and tissue-specific expression patterns of the murine ADH gene family. J. Biol. Chem. 1995a;270:10868-10877.
62. Zgombic-Knight M, Foglio MH, Duester G. Genomic structure and expression of the ADH7 gene encoding human class IV alcohol dehydrogenase, the form most efficient for retinol metabolism in vitro. J. Biol. Chem. 1995b;270:4305-4311.
63. Zile M, Bunge EC, DeLuca HF. Effect of vitamin A deficiency on intestinal proliferation in the rat. J. Nutr. 1997;107:552-560.