The enigma of fetal alcohol neurotoxicity

Annals of Medicine

Volumn 34, Issue 2, 2002, Pages 109-119

  Olney, John W ^a   Wozniak, David F ^a   Farber, Nuri B ^a   Jevtovic Todorovic, Vesna ^a   Bittigau, Petra ^a   Ikonomidou, Chrysanthy ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alcohol; Apoptosis; Ethanol; Fetal alcohol syndrome; GABA; Glutamate; Neurodegeneration

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ALCOHOL; ANESTHETIC AGENT; ANTICONVULSIVE AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; GLUTAMATE RECEPTOR; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITROUS OXIDE; PHENCYCLIDINE;

ALCOHOL INTOXICATION; APOPTOSIS; BRAIN GROWTH; DRUG ABUSE; FETAL ALCOHOL SYNDROME; GESTATIONAL AGE; GROWTH ACCELERATION; HUMAN; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYNAPTOGENESIS;

ALCOHOL-INDUCED DISORDERS, NERVOUS SYSTEM; ALCOHOLIC INTOXICATION; ANIMALS; APOPTOSIS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FEMALE; FETAL ALCOHOL SYNDROME; HUMANS; MICE; NERVE DEGENERATION; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0036260254     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.1080/07853890252953509     Document Type: Review

References (43)

1. Recognition of the fetal alcohol syndrome in early infancy
2. Pattern of malformation in offspring of chronic alcoholic mothers
3. Magnetic resonance imaging of brain anomalies in fetal alcohol syndrome
4. Brain malformations related to prenatal exposure to ethanol
5. Neuropsychiatric implications and long-term consequences of fetal alcohol spectrum disorders
6. Mental illness in adults with fetal alcohol syndrome or fetal alcohol effects
7. The fetal alcohol syndrome
8. Identifying maternal self-reported alcohol use associated with fetal alcohol spectrum disorders
9. Blockade of glutamate receptors triggers apoptotic neurodegeneration in the developing brain
10. Ethanol-induced apoptotic neurodegeneration and the fetal alcohol syndrome
11. The brain growth spurt in various mammalian species
12. Cell death: The significance of apoptosis
13. Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain
14. Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis
15. Apoptosis: A basic biological phenomenon with wideranging implications in tissue kinetics
16. Apoptosis in the in vivo mammalian forebrain
17. Prevention of trauma-induced neurodegeneration in infant rat brain
18. Apoptotic cell death triggered by head injury in infant rats is potentiated by NMDA antagonists
19. N-methyl-D-aspartate receptors and ethanol: Inhibition of calcium flux and cyclic GMP production
20. Ethanol inhibits NMDA-activated ion current in hippocampal neurons
21. A responses in cells stably transfected with receptor subunits
22. Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain
23. An improved cupric-silver method for impregnation of axonal and terminal degeneration
24. Ethanol-induced caspase-3 activation in the in vivo developing mouse brain
25. Antiepileptic drugs which block sodium channels cause neuronal apoptosis in the developing rat brain
26. Histological characterization of apoptotic neurodegeneration induced in the developing rat brain by drugs that block sodium channels
27. Neural activity and survival in the developing nervous system
28. Slow death of postnatal hippocampal neurons by GABA(A) receptor overactivation
29. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
30. NMDA antagonist neurotoxicity: Mechanism and prevention
31. Multifocal brain damage induced by phencyclidine is augmented by pilocarpine
32. Disseminated corticolimbic neuronal degeneration induced in rat brain by MK801
33. Age-specific neurotoxicity in the rat associated with NMDA receptor blockade: Potential relevance to schizophrenia?
34. Halothane prevents MK801 neurotoxicity in the rat cingulate cortex
35. Isoflurane and propofol block neurotoxicity caused by MK801 in the rat posterior cingulate/retrosplenial cortex
36. A receptors blocks neurotoxicity in the adult brain, but augments neurotoxicity in the developing brain
37. Deficits in small interneurons in cingulate cortex of schizophrenic and schizoaffective patients
38. The density of pyramidal and non-pyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects
39. Thalamic abnormalities in schizophrenia visualized through magnetic resonance image averaging
40. Association of prenatal phenobarbital and phenytoin exposure with small head size and with learning problems
41. Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin
42. Effect of nitrous oxide on excitatory and inhibitory synaptic transmission in hippocampal cultures