-
1
-
-
0017258698
-
Single-channel currents recorded from membrane of denervated frog muscle fibres
-
Neher E., Sakmann B., Single-channel currents recorded from membrane of denervated frog muscle fibres, Nature 1976, 260(5554), 799-802.
-
(1976)
Nature
, vol.260
, Issue.5554
, pp. 799-802
-
-
Neher, E.1
Sakmann, B.2
-
2
-
-
0019441262
-
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
-
Hamill O. P., Marty A., Neher E., Sakmann B., Sigworth F. J., Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches, Pflugers Arch. 1981, 391(2), 85-100.
-
(1981)
Pflugers Arch.
, vol.391
, Issue.2
, pp. 85-100
-
-
Hamill, O.P.1
Marty, A.2
Neher, E.3
Sakmann, B.4
Sigworth, F.J.5
-
3
-
-
0021288941
-
Patch clamp techniques for studying ionic channels in excitable membranes
-
Review
-
Sakmann B., Neher E., Patch clamp techniques for studying ionic channels in excitable membranes, Annu Rev. Physiol. 1984, 46, 455-472. (Review.)
-
(1984)
Annu Rev. Physiol.
, vol.46
, pp. 455-472
-
-
Sakmann, B.1
Neher, E.2
-
4
-
-
0036107267
-
Patch clamp on a chip
-
Sigworth F. J., Klemic K. G., Patch clamp on a chip, Biophys. J. 2002, 82(6), 2831-2832.
-
(2002)
Biophys. J.
, vol.82
, Issue.6
, pp. 2831-2832
-
-
Sigworth, F.J.1
Klemic, K.G.2
-
5
-
-
1942529811
-
Automated electrophysiology: high throughput of art
-
Wang X., Li M., Automated electrophysiology: high throughput of art, Assay Drug Dev. Technol. 2003, 1(5), 695-708.
-
(2003)
Assay Drug Dev. Technol.
, vol.1
, Issue.5
, pp. 695-708
-
-
Wang, X.1
Li, M.2
-
6
-
-
1942517758
-
Patch clamping by numbers
-
Wood C.,Williams C.,Waldron G. J., Patch clamping by numbers, Drug Discovery Today 2004, 9(10), 434-441.
-
(2004)
Drug Discovery Today
, vol.9
, Issue.10
, pp. 434-441
-
-
Wood, C.1
Williams, C.2
Waldron, G.J.3
-
7
-
-
33846855062
-
Patch clamp electrophysiology steps up a gear
-
Trezise, D. J., Patch clamp electrophysiology steps up a gear, Eur. Pharm. Rev. 2005, 2, 69-73.
-
(2005)
Eur. Pharm. Rev.
, vol.2
, pp. 69-73
-
-
Trezise, D.J.1
-
8
-
-
0026738801
-
Patch clamp techniques: an overview
-
Cahalan M., Neher E., Patch clamp techniques: an overview, Methods Enzymol. 1992, 207, 3-14.
-
(1992)
Methods Enzymol.
, vol.207
, pp. 3-14
-
-
Cahalan, M.1
Neher, E.2
-
9
-
-
33645902542
-
Patch Clamping: an Introductory Guide to Patch Clamp Electrophysiology
-
John Wiley & Sons Ltd
-
Molleman, A., Patch Clamping: an Introductory Guide to Patch Clamp Electrophysiology, John Wiley & Sons Ltd, 1992.
-
(1992)
-
-
Molleman, A.1
-
10
-
-
0036106307
-
Whole cell patch clamp recording performed on a planar glass chip
-
Fertig N., Blick R. H., Behrends J. C., Whole cell patch clamp recording performed on a planar glass chip, Biophys. J. 2002, 82(6), 3056-3062.
-
(2002)
Biophys. J.
, vol.82
, Issue.6
, pp. 3056-3062
-
-
Fertig, N.1
Blick, R.H.2
Behrends, J.C.3
-
11
-
-
0037236253
-
Microstructured apertures in planar glass substrates for ion channel research
-
Fertig N., George M., Klau M., Meyer C.,Tilke A., Sobotta C., Blick R. H., Behrends J. C., Microstructured apertures in planar glass substrates for ion channel research, Receptors Channels 2003, 9(1), 29-40.
-
(2003)
Receptors Channels
, vol.9
, Issue.1
, pp. 29-40
-
-
Fertig, N.1
George, M.2
Klau, M.3
Meyer, C.4
Tilke, A.5
Sobotta, C.6
Blick, R.H.7
Behrends, J.C.8
-
12
-
-
0041888478
-
Ionworks HT: a new highthroughput electrophysiology measurement platform
-
Schroeder K., Neagle B.,Trezise D. J.,Worley J., Ionworks HT: a new highthroughput electrophysiology measurement platform, J. Biomol. Screen. 2003, 8(1), 50-64.
-
(2003)
J. Biomol. Screen.
, vol.8
, Issue.1
, pp. 50-64
-
-
Schroeder, K.1
Neagle, B.2
Trezise, D.J.3
Worley, J.4
-
13
-
-
0028809337
-
The jellyfish green fluorescent protein: a new tool for studying ion channel expression and function
-
Marshall J., Molloy R., Moss G. W., Howe J. R., Hughes T. E., The jellyfish green fluorescent protein: a new tool for studying ion channel expression and function, Neuron 1995, 14(2), 211-215.
-
(1995)
Neuron
, vol.14
, Issue.2
, pp. 211-215
-
-
Marshall, J.1
Molloy, R.2
Moss, G.W.3
Howe, J.R.4
Hughes, T.E.5
-
14
-
-
0037474225
-
Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells
-
Crociani O., Guasti L., Balzi M., Becchetti A.,Wanke E., Olivotto M., Wymore R. S., Arcangeli A., Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells, J. Biol. Chem. 2003, 278(5), 2947-2955.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.5
, pp. 2947-2955
-
-
Crociani, O.1
Guasti, L.2
Balzi, M.3
Becchetti, A.4
Wanke, E.5
Olivotto, M.6
Wymore, R.S.7
Arcangeli, A.8
-
15
-
-
21144435502
-
Human ether-a-gogo-related gene 1 channels are physically linked to {beta}1 integrins and modulate adhesion-dependent signaling
-
Cherubini A. et al., Human ether-a-gogo-related gene 1 channels are physically linked to {beta}1 integrins and modulate adhesion-dependent signaling, Mol. Biol. Cell 2005, 16(6), 2972-2983.
-
(2005)
Mol. Biol. Cell
, vol.16
, Issue.6
, pp. 2972-2983
-
-
Cherubini, A.1
-
16
-
-
0002359693
-
Science and technology of patch recording electrodes
-
Sakmann, B., Neher, E. (Eds.), Plenum Press, New York
-
Corey D. P., Stevens, C. F., Science and technology of patch recording electrodes, in Single Channel Recording, Sakmann, B., Neher, E. (Eds.), Plenum Press, New York 1983, pp. 53-86.
-
(1983)
Single Channel Recording
, pp. 53-86
-
-
Corey, D.P.1
Stevens, C.F.2
-
17
-
-
0028012354
-
Lipid-glass adhesion in giga-sealed patch-clamped membranes
-
Opsahl L. R.,Webb W.W., Lipid-glass adhesion in giga-sealed patch-clamped membranes, Biophys. J. 1994, 66(1), 75-79.
-
(1994)
Biophys. J.
, vol.66
, Issue.1
, pp. 75-79
-
-
Opsahl, L.R.1
Webb, W.W.2
-
18
-
-
0035338920
-
Location is key-recent progress in single-cell-based high-throughput assays
-
Worley J., Li M., Location is key-recent progress in single-cell-based high-throughput assays, Drug Discovery Today 2001, 6(9), 454.
-
(2001)
Drug Discovery Today
, vol.6
, Issue.9
, pp. 454
-
-
Worley, J.1
Li, M.2
-
19
-
-
1942433697
-
A benchmark study with sealchip planar patch-clamp technology
-
Xu J., Guia A., Rothwarf D., Huang M., Sithiphong K., Ouang J., Tao G.,Wang X.,Wu L., A benchmark study with sealchip planar patch-clamp technology, Assay Drug Dev. Technol. 2003, 1(5), 675-684.
-
(2003)
Assay Drug Dev. Technol.
, vol.1
, Issue.5
, pp. 675-684
-
-
Xu, J.1
Guia, A.2
Rothwarf, D.3
Huang, M.4
Sithiphong, K.5
Ouang, J.6
Tao, G.7
Wang, X.8
Wu, L.9
-
20
-
-
20144389310
-
Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp
-
Dubin A. E. et al., Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp, J. Biomol. Screen. 2005, 10(2), 168-81.
-
(2005)
J. Biomol. Screen.
, vol.10
, Issue.2
, pp. 168-181
-
-
Dubin, A.E.1
-
21
-
-
84889830348
-
Rapid ICE (Rapid Ion Channel Electrophysiology): an ion channel screening service using the PatchXpress 7000A system
-
Presentation at Molecular Devices Electrophysiology User's Meeting, Long Beach CA, February
-
Quinn, C., Rapid ICE (Rapid Ion Channel Electrophysiology): an ion channel screening service using the PatchXpress 7000A system, Presentation at Molecular Devices Electrophysiology User's Meeting, Long Beach CA, February 2005.
-
(2005)
-
-
Quinn, C.1
-
22
-
-
1942529810
-
Characterization of potassium channel modulators with QPatch automated patch-clamp technology: system characteristics and performance
-
Kutchinsky J. et al., Characterization of potassium channel modulators with QPatch automated patch-clamp technology: system characteristics and performance, Assay Drug Dev. Technol. 2003, 1(5), 685-93.
-
(2003)
Assay Drug Dev. Technol.
, vol.1
, Issue.5
, pp. 685-693
-
-
Kutchinsky, J.1
-
23
-
-
0042895988
-
High throughput ionchannel pharmacology: planar-arraybased voltage clamp
-
Kiss L., Bennett P. B., Uebele V. N., Koblan K. S., Kane S. A., Neagle B., Schroeder K., High throughput ionchannel pharmacology: planar-arraybased voltage clamp, Assay Drug Dev. Technol. 2003, 1(2), 127-35.
-
(2003)
Assay Drug Dev. Technol.
, vol.1
, Issue.2
, pp. 127-135
-
-
Kiss, L.1
Bennett, P.B.2
Uebele, V.N.3
Koblan, K.S.4
Kane, S.A.5
Neagle, B.6
Schroeder, K.7
-
24
-
-
22444443481
-
Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation
-
in press
-
Guo L., Guthrie H., Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation, J. Pharmacol. Toxicol. Methods 2005, in press.
-
(2005)
J. Pharmacol. Toxicol. Methods
-
-
Guo, L.1
Guthrie, H.2
-
25
-
-
0015823874
-
Aqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B
-
Finkelstein A., Holz R., Aqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B, Membranes 1973, 2, 377-408.
-
(1973)
Membranes
, vol.2
, pp. 377-408
-
-
Finkelstein, A.1
Holz, R.2
-
26
-
-
0031766409
-
Perforated patch recording with beta-escin
-
Fan J. S., Palade P., Perforated patch recording with beta-escin, Pflugers Arch. 1998, 436(6), 1021-1023.
-
(1998)
Pflugers Arch.
, vol.436
, Issue.6
, pp. 1021-1023
-
-
Fan, J.S.1
Palade, P.2
-
27
-
-
0026756316
-
Access resistance and space clamp problems associated with whole-cell patch clamping
-
Armstrong C. M., GillyW. F., Access resistance and space clamp problems associated with whole-cell patch clamping, Methods Enzymol. 1992, 207, 100-122.
-
(1992)
Methods Enzymol.
, vol.207
, pp. 100-122
-
-
Armstrong, C.M.1
Gilly, W.F.2
-
28
-
-
1942465537
-
High quality ion channel analysis on a chip with the NPC technology
-
Bruggemann A., George M., Klau M., Beckler M., Steindl J., Behrends J. C., Fertig N., High quality ion channel analysis on a chip with the NPC technology, Assay Drug Dev. Technol. 2003, 1(5), 665-673.
-
(2003)
Assay Drug Dev. Technol.
, vol.1
, Issue.5
, pp. 665-673
-
-
Bruggemann, A.1
George, M.2
Klau, M.3
Beckler, M.4
Steindl, J.5
Behrends, J.C.6
Fertig, N.7
-
29
-
-
10244245061
-
Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compounds
-
Tao H. et al., Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compounds, Assay Drug Dev. Technol. 2004, 2(5), 497-506.
-
(2004)
Assay Drug Dev. Technol.
, vol.2
, Issue.5
, pp. 497-506
-
-
Tao, H.1
-
30
-
-
0037115389
-
A cell-based bar code reader for high-throughput screening of ion channel-ligand interactions
-
Sinclair J., Pihl J., Olofsson J., Karlsson M., Jardemark K., Chiu D. T., Orwar O., A cell-based bar code reader for high-throughput screening of ion channel-ligand interactions, Anal Chem. 2002, 74(24), 6133-6138.
-
(2002)
Anal Chem.
, vol.74
, Issue.24
, pp. 6133-6138
-
-
Sinclair, J.1
Pihl, J.2
Olofsson, J.3
Karlsson, M.4
Jardemark, K.5
Chiu, D.T.6
Orwar, O.7
-
31
-
-
4444339717
-
A microfluidics approach to the problem of creating separate solution environments accessible from macroscopic volumes
-
Olofsson J., Pihl J., Sinclair J., Sahlin E., Karlsson M., Orwar O., A microfluidics approach to the problem of creating separate solution environments accessible from macroscopic volumes, Anal Chem. 2004, 76(17), 4968-4976.
-
(2004)
Anal Chem.
, vol.76
, Issue.17
, pp. 4968-4976
-
-
Olofsson, J.1
Pihl, J.2
Sinclair, J.3
Sahlin, E.4
Karlsson, M.5
Orwar, O.6
-
32
-
-
0033003760
-
A Simple Statistical Parameter for Use in Evaluation andValidation of High Throughput Screening Assays
-
Zhang J. H., Chung T. D., Oldenburg K. R., A Simple Statistical Parameter for Use in Evaluation andValidation of High Throughput Screening Assays, J. Biomol. Screen. 1999, 4(2), 67-73.
-
(1999)
J. Biomol. Screen.
, vol.4
, Issue.2
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
33
-
-
0003443746
-
Ion Channels of Excitable Membranes
-
Sinauer Verlag, Sunderland MA
-
Hille, B., Ion Channels of Excitable Membranes, Sinauer Verlag, Sunderland MA, 2001.
-
(2001)
-
-
Hille, B.1
-
34
-
-
0029952101
-
K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current
-
Barhanin J., Lesage F., Guillemare E., Fink M., Lazdunski M., Romey G., K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current, Nature 1996, 384(6604), 78-80.
-
(1996)
Nature
, vol.384
, Issue.6604
, pp. 78-80
-
-
Barhanin, J.1
Lesage, F.2
Guillemare, E.3
Fink, M.4
Lazdunski, M.5
Romey, G.6
-
35
-
-
0029854263
-
Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel
-
Sanguinetti M. C., Curran M. E., Zou A., Shen J., Spector P. S., Atkinson D. L., Keating M. T., Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel, Nature 1996, 384(6604), 80-83.
-
(1996)
Nature
, vol.384
, Issue.6604
, pp. 80-83
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Zou, A.3
Shen, J.4
Spector, P.S.5
Atkinson, D.L.6
Keating, M.T.7
-
36
-
-
0038575824
-
Molecular determinants of KCNQ1 channel block by a benzodiazepine
-
Seebohm G., Chen J., Strutz N., Culberson C., Lerche C., Sanguinetti M. C., Molecular determinants of KCNQ1 channel block by a benzodiazepine, Mol. Pharmacol. 2003, 64(1), 70-77.
-
(2003)
Mol. Pharmacol.
, vol.64
, Issue.1
, pp. 70-77
-
-
Seebohm, G.1
Chen, J.2
Strutz, N.3
Culberson, C.4
Lerche, C.5
Sanguinetti, M.C.6
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