Characterization of Potassium Channel Modulators with QPatch™ Automated Patch-Clamp Technology: System Characteristics and Performance

Assay and Drug Development Technologies

Volumn 1, Issue 5, 2003, Pages 685-693

  Kutchinsky, Jonatan ^a   Friis, Søren ^a   Asmild, Margit ^a   Taboryski, Rafael ^a   Pedersen, Simon ^a   Vestergaard, Ras K ^a   Jacobsen, Rasmus B ^a   Krzywkowski, Karen ^a   Schrøder, Rikke L ^a   Ljungstrøm, Trine ^a   Hélix, Nathalie ^a   Sørensen, Claus B ^a   Bech, Morten ^a   Willumsen, Niels J ^a,b  

^a Sophion Bioscience A/S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL; ARTICLE; BIOTECHNOLOGY; CELL CULTURE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHO CELL; COMPARATIVE STUDY; CRICETULUS; CULTURE TECHNIQUE; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; ELECTROPHYSIOLOGY; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; FEASIBILITY STUDY; HAMSTER; HUMAN; INSTRUMENTATION; KIDNEY; METHODOLOGY; MICROELECTRODE; PATCH CLAMP; PHYSIOLOGY; REPRODUCIBILITY; ROBOTICS; SENSITIVITY AND SPECIFICITY; VALIDATION STUDY;

ANIMALS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; ELECTROPHYSIOLOGY; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEASIBILITY STUDIES; HUMANS; ION CHANNEL GATING; KIDNEY; MEMBRANE POTENTIALS; MICROELECTRODES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; REPRODUCIBILITY OF RESULTS; ROBOTICS; SENSITIVITY AND SPECIFICITY;

EID: 1942529810     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/154065803770381048     Document Type: Article

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