Anti-tumor and anti-angiogenic activity of novel hydantoin derivatives: Inhibition of VEGF secretion in liver metastatic osteosarcoma cells

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 14, 2009, Pages 4928-4934

  Basappa, ^a,c   Ananda Kumar, C S ^b   Nanjunda Swamy, S ^b   Sugahara, Kazuyuki ^a   Rangappa, Kanchugarakoppal S ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UNIVERSITY OF MYSORE   (India)

^c BANGALORE UNIVERSITY   (India)

Author keywords

Anti angiogenesis; Anti tumor; Hydantoin; Metastasis; VEGF

Indexed keywords

8 (3 FLUOROBENZYL) 10 [4 (METHYLSULFONYL)BENZYL] 8 AZASPIRO(BICYCLO[3.2.1]OCTANE 3,40 IMIDAZOLIDINE) 20,50 DIONE; 8 (3,4 DIFLUOROBENZYL) 10 [4 (METHYLSULFONYL)BENZYL] 8 AZASPIRO(BICYCLO[3.2.1]OCTANE 3,40 IMIDAZOLIDINE) 20,50 DIONE; HYDANTOIN DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG STRUCTURE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; LIVER METASTASIS; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL; STRUCTURE ACTIVITY RELATION;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; HYDANTOINS; LIVER; LIVER NEOPLASMS; MICE; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PATHOLOGIC; OSTEOSARCOMA; OVARIAN NEOPLASMS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MURINAE;

EID: 67650095563     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.06.004     Document Type: Article

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