Novel chondroitin sulfate-binding cationic liposomes loaded with cisplatin efficiently suppress the local growth and liver metastasis of tumor cells in vivo

Cancer Research

Volumn 62, Issue 15, 2002, Pages 4282-4288

  Lee, Chun Man ^a   Tanaka, Toshiyuki ^a   Murai, Toshiyuki ^a   Kondo, Masayo ^b   Kimura, Junji ^b   Su, Wei ^a   Kitagawa, Toru ^a   Ito, Toshinori ^a   Matsuda, Hikaru ^a   Miyasaka, Masayuki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TERUMO CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3,5 DIPENTADECYLOXYBENZAMIDINE; BENZAMIDINE DERIVATIVE; CHONDROITIN 4 SULFATE; CHONDROITIN SULFATE; CHONDROITIN SULFATE BINDING CATIONIC LIPOSOME; CHONDROITIN SULFATE D; CHONDROITIN SULFATE E; CISPLATIN; DERMATAN SULFATE; LIPOSOME; MACROGOL; TRX 20; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL GROWTH; CELL SURFACE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; DRUG TARGETING; FEMALE; HUMAN; HUMAN CELL; LIVER CANCER; LIVER METASTASIS; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; TUMOR GROWTH;

ANIMALS; CATIONS; CELL DIVISION; CHONDROITIN SULFATES; CISPLATIN; FEMALE; HUMANS; LIPOSOMES; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C3H; MICE, INBRED ICR; MICE, NUDE; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036682017     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Proteoglycans: Structures and interactions
2. CD44-related chondroitin sulfate proteoglycan, a cell surface receptor implicated with tumor cell invasion, mediates endothelial cell migration on fibrinogen and invasion into a fibrin matrix
3. A role of chondroitin sulfate glycosaminoglycan binding site in α4β1 integrin-mediated melanoma cell adhesion
4. Endocan is a novel chondroitin sulfate/dermatan sulfate proteoglycan which promotes hepatocyte growth factor/scatter factor mitogenic activity
5. Melanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen
6. Evidence for an interaction of herpes simplex virus with chondroitin sulfate proteoglycans during infection
7. Biology of disease: Proteoglycans: Structure, function, and role in neoplasia
8. Proteoglycans and neoplasia
9. Sulfated mucopolysaccharides from normal and virus transformed rodent fibroblasts
10. Partial characterization of proteoglycans isolated from neoplastic and nonneoplastic human breast tissues
11. Glycosaminoglycans in human breast cancer
12. Human tumor antigens
13. Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells
14. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors
15. Polyethylene glycol modification: Relevance of improved methodology to turnout targeting
16. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
17. Possibility of active targeting to tumor tissues with liposomes
18. Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice
19. Therapy of a xenografted human colonic carcinoma using cisplatin or doxorubicin encapsulated in long-circulating pegylated stealth liposomes
20. Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma
21. Liposomes as vehicles for targeted therapy of cancer. Part 2: Clinical development
22. Preferential binding of polyethylene glycol-coated liposomes containing a novel cationic lipid, TRX-20, to human subendothelial cells via chondroitin sulfate
23. Effect of steroid-liposome on immunohistopathology of IgA nephropathy in ddY mice
24. Establishment and characterization of a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung
25. Immunocytochemical localization of native chondroitin-sulfate in tissues and cultured cells using specific monoclonal antibody
26. Structural domains in chondroitin sulfate identified by anti-chondroitin sulfate monoclonal antibodies. Immunosequencing of chondroitin sulfates
27. Novel cell proliferation and cytotoxicity assays using a tetrazolium salt that produces a water-soluble formazan dye
28. A rapid method of total lipid extraction and purification
29. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma
30. Antibody targeting of doxorubicine-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice
31. Ligand-targeted liposomes
32. Immunolocalization of hyaluronic acid and inter-α-trypsin inhibitor in mice
33. Cell surface chondroitin sulfate proteoglycans in tumor cell adhesion, motility and invasion
34. A cell surface chondroitin sulfate proteoglycan, immunologically related to CD44, is involved in type I collagen-mediated melanoma cell motility and invasion
35. Pharmacological studies of cisplatin encapsulated in long-circulating liposomes in mouse tumor models
36. Pancreatic carcinoma is characterized by elevated content of chondroitin sulfate with altered disaccharide composition
37. Proteoglycan changes in the intercellular matrix of human colon carcinoma: An integrated biochemical and stereologic analysis
38. Distribution and changes of glycosaminoglycans in neoplasias of rectum
39. Altered glycosaminoglycan composition in reactive and neoplastic human liver
40. Analysis of glycosaminoglycans in human prostate by high-performance liquid chromatography
41. Increased content of chondroitin sulfate proteoglycan in human colorectal carcinoma metastases compared with the primary tumor as determined by an anti-chondroitin-sulfate monoclonal antibody
42. Anti-tumor activities of chondroitinase AC and chondroitinase B: Inhibition of angiogenesis, proliferation, and invasion