Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 15, 2009, Pages 4079-4083

  Xu, Peng ^a   Liu, Lu ^a   Chen, Xiao zhuo ^a   Li, Yun ^b   Liu, Jian ^b   Jin, Zhi ping ^c   Wang, Guang qiang ^c   Lei, Ping sheng ^a  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b PEKING UNIVERSITY   (China)

^c Jingxin Pharmaceutical Co   (China)

Author keywords

Acylide; Antibacterial activity; Ketolide; Structure modification

Indexed keywords

CLARITHROMYCIN; ERYTHROMYCIN; HYDROXYL GROUP; IMIDAZO[4,5 B]PYRIDINYL SULFUR; KETOLIDE; MACROLIDE; PYRIDINE DERIVATIVE; TELITHROMYCIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; CLARITHROMYCIN; DRUG DESIGN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ERYTHROMYCIN; HUMANS; IMIDAZOLES; KETOLIDES; MACROLIDES; MICROBIAL SENSITIVITY TESTS; MODELS, CHEMICAL; RESPIRATORY TRACT INFECTIONS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; SULFIDES; SULFUR;

EID: 67649993432     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.06.023     Document Type: Article

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