Quantitation of SAR97276 in mouse tissues by rapid resolution liquid chromatography-mass spectrometry

Journal of Separation Science

Volumn 32, Issue 11, 2009, Pages 1808-1815

  Margout, Delphine ^a   Wein, Sharon ^b   Gandon, Hermine ^a   Gattacceca, Florence ^a   Vial, Henri J ^b   Bressolle, Françoise M M ^a  

^a UNIV MONTPELLIER   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

Antimalarial drug; Pharmacokinetic study; RRLC ESI MS; SAR97276; Tissue distribution

Indexed keywords

ANTIMALARIAL DRUG; PHARMACOKINETIC STUDY; RRLC-ESI-MS; SAR97276; TISSUE DISTRIBUTION;

CHROMATOGRAPHIC ANALYSIS; HISTOLOGY; LIQUID CHROMATOGRAPHY; LIQUID NITROGEN; LIQUIDS; MASS SPECTROMETRY; PHARMACOKINETICS;

TISSUE;

1,12 DODECAMETHYLENEBIS [4 METHYL 5 (2 HYDROXYETHYL)THIAZOL 3 IUM] DIBROMIDE; 1,12 DODECAMETHYLENEBIS [4 METHYL 5 (2 METHOXYETHYL)THIAZOL 3 IUM] DIBROMIDE; ANTIMALARIAL AGENT; CITRIC ACID; LIOTHYRONINE; SAR 97276; T 4; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG ISOLATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FLOW RATE; HEART; LIQUID CHROMATOGRAPHY; LIVER LEVEL; MASS SPECTROMETRY; MOUSE; NONHUMAN; PH; PHASE SEPARATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; TISSUE DISTRIBUTION; TISSUE HOMOGENATE;

ANIMALS; BRAIN; CALIBRATION; CHROMATOGRAPHY, LIQUID; FEMALE; HEART; LIVER; MASS SPECTROMETRY; MICE; MOLECULAR STRUCTURE; THIAZOLES; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 67649970217     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900059     Document Type: Article

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