Prodrugs of bisthiazolium salts are orally potent antimalarials

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 43, 2004, Pages 15458-15463

  Vial, Henri J ^a   Wein, Sharon ^a   Farenc, Christine ^a   Kocken, Clemens ^b   Nicolas, Olivier ^c   Ancelin, Marie Laure ^a   Bressolle, Francoise ^c   Thomas, Alan ^b   Calas, Michèle ^a  

^a CNRS   (France)

^b BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^c UNIV MONTPELLIER   (France)

Author keywords

Chemotherapy; Drug resistance; Malaria; Phospholipid metabolism; Plasmodium

Indexed keywords

HEMOZOIN; PHOSPHATIDYLCHOLINE; THIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG EFFICACY; DRUG POTENCY; DRUG PROTEIN BINDING; LIPID METABOLISM; MALARIA; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM CYNOMOLGI; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; ANTIMALARIALS; FEMALE; MACACA MULATTA; MICE; PLASMODIUM FALCIPARUM; PRODRUGS; THIAZOLES;

ANIMALIA; MACACA MULATTA; MURINAE; PLASMODIUM CYNOMOLGI; PROTOZOA;

EID: 7444260721     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0404037101     Document Type: Article

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