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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 820, Issue 1, 2005, Pages 83-93

Liquid chromatography-electrospray mass spectrometry determination of a bis-thiazolium compound with potent antimalarial activity and its neutral bioprecursor in human plasma, whole blood and red blood cells

(6) Nicolas, Olivier a Margout, Delphine a Taudon, Nicolas a Calas, Michele a Vial, Henri J b Bressolle, Françoise a

a UNIV MONTPELLIER (France)

b UNIVERSITÉ DE MONTPELLIER (France)

Author keywords

Antimalarial activity; Bis thiazolium compound; Human plasma; Liquid chromatography electrospray mass spectrometry; Neutral bioprecursor; Red blood cells; Validation; Whole blood

Indexed keywords

BLOOD; CELLS; DISEASE CONTROL; DRUG PRODUCTS; IONIZATION; MASS SPECTROMETRY; SOLVENT EXTRACTION;

BIS-THIAZOLIUM; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; HUMAN PLASMA; SOLID PHASE EXTRACTION;

LIQUID CHROMATOGRAPHY;

1,12 BIS[4 METHYL 5 (2 HYDROXYETHYL) 3 THIAZOL 3 IUM 3 YL]DODECANE DIBROMIDE; ACETONITRILE; AMMONIA; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; VERAPAMIL;

ACCURACY; ANALYTIC METHOD; ANTIMALARIAL ACTIVITY; ARTICLE; AUTOMATION; BLOOD; CALIBRATION; CONTROLLED STUDY; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; ERYTHROCYTE; FLOW RATE; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; PLASMA; PRIORITY JOURNAL; PROTON TRANSPORT; SOLID PHASE EXTRACTION;

EID: 18144366635 PISSN: 15700232 EISSN: None Source Type: Journal
DOI: 10.1016/j.jchromb.2005.03.022 Document Type: Article

Times cited : (7)

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