Abnormal postpartum renal development and cystogenesis in the bcl-2 (-/-) mouse

American Journal of Physiology

Volumn 271, Issue 1 PART 2, 1996, Pages

  Sorenson, Christine M ^a,b   Padanilam, Babu J ^a   Hammerman, Marc R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Renal Division   (United States)

Author keywords

Apoptosis; Bax protein; Hypoplasia; Polycystic kidney disease

Indexed keywords

PROTEIN BCL 2;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B CELL LEUKEMIA; DNA SYNTHESIS; HISTOPATHOLOGY; KIDNEY DEVELOPMENT; KIDNEY FAILURE; KIDNEY HYPOPLASIA; KIDNEY MASS; KIDNEY POLYCYSTIC DISEASE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BROMODEOXYURIDINE; CELL DIVISION; GENE DELETION; KIDNEY; MICE; POLYCYSTIC KIDNEY DISEASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REFERENCE VALUES;

EID: 0029756776     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajprenal.1996.271.1.f184     Document Type: Article

References (26)

1. Bernstein, J. Renal hypoplasia and dysplasia. In: Pédiatrie Kidney Disease, edited by C. M. Edelmann, Jr. Boston, MA: Little Brown, 1992, p. 1121-1137.
2. Calvet, J. P. Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation? Kidney Int. 43: 101-108, 1993.
3. Calvet, J. P. Injury and development in polycystic kidney disease. Current Opin. Nephrol. Hypertens. 3: 340-348, 1994.
4. Carone, F. A., R. Bacallao, and Y. S. Kanwar. Biology of disease: biology of polycystic kidney disease. Lab. Invest. 70: 437-448, 1994.
5. Chandler, D., A. K. El-Naggar, S. Brisbay, R. W. Redline, and T. J. McDonnell. Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney: evidence for the contribution of bcl-2 expression to renal carcinogenesis. Human Pathol. 25: 789-796, 1994.
6. Cohn, S, J., and M. W. Lieberman. The use of antibodies to 4-bromo-2'-deoxyuridine for the isolation of DNA sequences. J. Biol. Chem. 259: 12456-12462, 1984.
7. Coles, H. S. R., J. F. Burne, and M. C. Raff. Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development 118: 777-784, 1993.
8. Dunnett, C. W. New tables for multiple comparisons with a control. Biometrics 20: 482-491, 1964.
9. Fick, G, M., and P. Gabow. Hereditary and acquired cystic disease of the kidney. Kidney Int. 46: 951-964, 1994.
10. Gabow, P. Polycystic kidney disease: clues to pathogenesis. Kidney Int. 40: 989-996, 1991.
11. Gavrieli, Y., Y. Sherman, and S. A. Ben-Sasson. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119: 493-501, 1992.
12. Grantham, J. J. Fluid secretion, cellular proliferation, and the pathogenesis of renal epithelial cysts. J. Am. Soc. Nephrol. 3: 1843-1857, 1993.
13. Hammerman, M. R. Growth factors in renal development. Semin. Nephrol. 15: 291-299, 1995.
14. Holthofer, H. Lectin binding sites in kidney. J. Histochem. Cytochem. 31: 531-537, 1983.
15. Knudson, C. M., K. S. K. Tung, W. G. Tourtellotte, G. A. J. Brown, and S. J. Korsmeyer. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science Wash. DC 270: 96-99, 1995.
16. Koseki, C., D. Herzlinger, and A. Al-Awqati. Apoptosis in metanephric development. J. Cell Biol. 119: 1327-1333, 1992.
17. Miller, S. B., P. Rotwein, J. D. Bortz, P. J. Bechtel, V. A. Hansen, S. A. Rogers, and M. R. Hammerman. Renal expression of IGF I in hypersomatotrophic states. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F251-F257, 1990.
18. Munakata, S., and J. B. Hendricks. Effect of fixation time and microwave oven heating time on retrieval of the Ki-67 antigen from paraffin-embedded tissue. J. Histochem. Cytochem. 41: 1241-1246, 1993.
19. Oltvai, Z. N., C. L. Milliman, and S. J. Korsmeyer. Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerated programed cell death. Cell 74: 609-619, 1993.
20. Reed, J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124: 1-6, 1994.
21. Savill, J. Apoptosis and the kidney. J. Am. Soc. Nephrol. 5: 12-21, 1994.
22. Schulte, B. A., and S. S. Spicer. Histochemical evaluation of mouse and rat kidneys with lectin horseradish peroxidase conjugates. am. J. Anat. 168: 345-362, 1983.
23. Sorenson, C. M., S. A. Rogers, S. J. Korsmeyer, and M. R. Hammerman. Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F73-F81, 1995.
24. Welling, L. W., and J. J. Grantham. Cystic and developmental diseases of the kidney. In: The Kidney, edited by B. M. Brenner and F. C. Rector, Jr., Philadelphia, PA: Saunders, 1991.
25. Wilson, P. D., and A. C. Sherwood. Tubulocystic epithelium. Kidney Int. 39: 450-463, 1991.
26. Veis, D. J., C. M. Sorenson, J. R. Shutter, and S. J. Korsmeyer. Bcl-2 deficient mice demonstrate fulminant lympoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75: 229-240, 1993.