Cytokines regulate fibroblast-like synovial cell differentiation to adipocyte-like cells

Rheumatology

Volumn 43, Issue 4, 2004, Pages 448-452

  Yamasaki, S ^a   Nakashima, T ^a   Kawakami, A ^a   Miyashita, T ^a   Tanaka, F ^a   Ida, H ^a   Migita, K ^a   Origuchi, T ^a   Eguchi, K ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adipogenesis; CCAAT enhancer binding protein; Cytokines; NF B; PPAR

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STROMELYSIN; TROGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; SYNOVIUM;

ADIPOCYTES; ARTHRITIS, RHEUMATOID; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMANS; CYTOKINES; FIBROBLASTS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MATRIX METALLOPROTEINASE 3; OSTEOARTHRITIS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SYNOVIAL MEMBRANE; THIAZOLIDINEDIONES; TRANSCRIPTION FACTORS;

EID: 1842833395     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/keh092     Document Type: Article

References (21)

1. Feldmann M, Brennan FM, Maini, RN. Rheumatoid arthritis. Cell 1996;85:307-10.
2. Arend WP. Physiology of cytokine pathways in rheumatoid arthritis. Arthritis Rheum 2001;45:101-6.
3. Yamasaki S, Nakashima T, Kawakami A et al. Functional alterations of rheumatoid fibroblast-like synovial cells through activation of PPARγ-mediated signaling pathway. Clin Exp Immunol 2002;129:379-84.
4. Bari CD, Dell'Accio F, Tylzanowski P, Luyten P. Multipotent mesenchymal stem cells from adult human synovial membrane. Arthritis Rheum 2001;44:1928-42.
5. Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 1994;79:1147-56.
6. 2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 1995;83:813-9.
7. Nanbu-Wakao R, Fujitani Y, Masuho Y, Muramatu M, Wakao H. Prolactin enhances CCAAT enhancer-binding protein-β (C/EBPβ) and peroxisome proliferator-activated receptor γ (PPARγ) messenger RNA expression and stimulates adipogenic conversion of NIH-3T3 cells. Mol Endocrinol 2000;14:307-16.
8. Meng L, Zhou J, Sasano H, Suzuki T, Zeitoun KM, Bulun SE. Tumor necrosis factor α and interleukin 11 secreted by malignant breast epithelial cells inhibit adipocyte differentiation by selectively down-regulating CCAAT/Enhancer binding protein α and peroxisome proliferator-activated receptor γ: Mechanism of desmoplastic reaction. Cancer Res 2001;61:2250-5.
9. Oates JC, Reilly CM, Crosby MB, Gilkeson GS. Peroxisome proliferator-activated receptor γ agonists: Potential use for treating chronic inflammatory diseases. Arthritis Rheum 2002;46:598-605.
10. 2 induces synoviocytes apoptosis and suppresses adjuvant-induced arthritis in rats. J Clin Invest 2000;106:189-97.
11. Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
12. Kawakami A, Nakashima T, Sakai H et al. Inhibition of caspase cascade by HTLV-I Tax through induction of NF-κB nuclear translocation. Blood 1999;94:3847-54.
13. Arend WP, Dayer JM. Cytokines and cytokine inhibitor or antagonists in rheumatoid arthritis. Arthritis Rheum 1990;33:305-15.
14. Baeuerle PA, Henkel T. Function and activation of NF-κB in the immune system. Annu Rev Immunol 1994;12:141-79.
15. Bond M, Baker AH, Newby AC. Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts. Biochem Biophys Res Commun 1999;264:561-7.
16. Yamanishi Y, Boyle DL, Rosengren S, Green DR, Zvaifler NJ, Firestein GS. Regional analysis of p53 mutations in rheumatoid arthritis synovium. Proc Natl Acad Sci USA 2002;99:10025-30.
17. Pap T, Franz JK, Hummel KM, Jeisy E, Gay R, Gay S. Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction. Arthritis Res 2000;2:59-64.
18. Suzawa M, Takada I, Yanagisawa J et al. Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade. Nature Cell Biol 2003;5:224-30.
19. Kinger AA, Jones DL, Schulz C, Rogers MB, Fuller MT. Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science 2001;294:2542-55.
20. Tulina N, Matunis E. Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science 2001;294:2546-9.
21. Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-7.