A unified scheme for initiation and conformational adaptation of human apolipoprotein E N-terminal domain upon lipoprotein binding and for receptor binding activity

Journal of Biological Chemistry

Volumn 284, Issue 21, 2009, Pages 14657-14666

  Sivashanmugan, Arun ^a   Wang, Jianjun ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN; APOLIPOPROTEIN E; H-BONDS; HELIX BUNDLE; HIGH RESOLUTION; HYDROPHILIC RESIDUES; N-TERMINAL DOMAINS; NMR STRUCTURES; OPEN CONFORMATION; PROTEIN-LIPID INTERACTIONS; RECEPTOR BINDING; RECEPTOR-BINDING DOMAINS; STRUCTURAL FEATURE;

BINDING SITES; HYDROPHILICITY; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CRYSTAL STRUCTURE;

APOLIPOPROTEIN E; APOLIPOPROTEIN E3; BUFFER; LIPOPROTEIN RECEPTOR;

ADAPTATION; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HUMAN; HYDROGEN BOND; HYDROPHILICITY; INTERMETHOD COMPARISON; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RECEPTOR BINDING; AMINO ACID SEQUENCE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; APOLIPOPROTEIN E3; BUFFERS; HUMANS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, LIPOPROTEIN; SEQUENCE ALIGNMENT;

EID: 67649785032     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M901012200     Document Type: Article

References (39)

1. Weisgraber, K. H. (1994) Adv. Protein Chem. 45, 249-302
2. Mahley, R. W., Huang, Y., and Weisgraber, K. H. (2006) J. Clin. Invest. 116, 1226-1229
3. Huang, Y., von Eckardstein, A., Wu, S., Maeda, N., and Assmann, G. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1834-1838
4. Mahley, R. W., and Rall, S. C., Jr. (2000) Annu. Rev. Genomics Hum. Genet. 1, 507-537
5. Wilson, C., Wardell, M. R., Weisgraber, K. H., Mahley, R. W., and Agard, D. A. (1991) Science 252, 1817-1822
6. Rudenko, G., and Deisenhofer, J. (2003) Curr. Opin. Struct. Biol. 13, 683-689
7. Morrow, J. A., Arnold, K. S., Dong, J., Balestra, M. E., Innerarity, T. L., and Weisgraber, K. H. (2000) J. Biol. Chem. 275, 2576-2580
8. Wardell, M. R., Rall, S. C., Jr., Schaefer, E. J., Kane, J. P., and Weisgraber, K. H. (1991) J. Lipid Res. 32, 521-528
9. Lalazar, A., and Mahley, R. W. (1989) J. Biol. Chem. 264, 8447-8450
10. Fisher, C. A., Wang, J., Francis, G. A., Sykes, B. D., Kay, C. M., and Ryan, R. O. (1997) Biochem. Cell Biol. 75, 45-53
11. Xu, C., Sivashanmugam, A., Hoyt, D., and Wang, J. (2005) J. Biomol. NMR 32, 177
12. Zheng, Y., Giovannelli, J. L., Ho, N. T., Ho, C., and Yang, D. (2004) J. Biomol. NMR 30, 423-429
13. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
14. Johnson, B. A., and Blevins, R. A. (1994) J. Biomol. NMR 4, 603-614
15. Garrett, D. S., Powers, R., Gronenborn, A. M., and Clore, G. M. (1991) J. Magn. Reson. 95, 214-220
16. Cornilescu, G., Delaglio, F., and Bax, A. (1999) J. Biomol. NMR 13, 289-302
17. Eghbalnia, H. R., Wang, L., Bahrami, A., Assadi, A., and Markley, J. L. (2005) J. Biomol. NMR 32, 71-81
18. Wishart, D. S., Sykes, B. D., and Richards, F. M. (1992) Biochemistry 31, 1647-1651
19. Guntert, P. (2004) Methods Mol. Biol. 278, 353-378
20. Willard, L., Ranjan, A., Zhang, H., Monzavi, H., Boyko, R. F., Sykes, B. D., and Wishart, D. S. (2003) Nucleic Acids Res. 31, 3316-3319
21. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
22. Hatters, D. M., Peters-Libeu, C. A., and Weisgraber, K. H. (2006) Trends Biochem. Sci. 31, 445-454
23. Hatters, D. M., Peters-Libeu, C. A., and Weisgraber, K. H. (2005) J. Biol. Chem. 280, 26477-26482
24. Gupta, V., Narayanaswami, V., Budamagunta, M. S., Yamamato, T., Voss, J. C., and Ryan, R. O. (2006) J. Biol. Chem. 281, 39294-39299
25. Breiter, D. R., Kanost, M. R., Benning, M. M., Wesenberg, G., Law, J. H., Wells, M. A., Rayment, I., and Holden, H. M. (1991) Biochemistry 30, 603-608
26. Fisher, C. A., Narayanaswami, V., and Ryan, R. O. (2000) J. Biol. Chem. 275, 33601-33606
27. Lu, B., Morrow, J. A., and Weisgraber, K. H. (2000) J. Biol. Chem. 275, 20775-20781
28. Peters-Libeu, C. A., Newhouse, Y., Hatters, D. M., and Weisgraber, K. H. (2006) J. Biol. Chem. 281, 1073-1079
29. Fan, D., Zheng, Y., Yang, D., and Wang, J. (2003) J. Biol. Chem. 278, 21212-21220
30. Wang, J., Sykes, B. D., and Ryan, R. O. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 1188-1193
31. Fisher, C. A., and Ryan, R. O. (1999) J. Lipid Res. 40, 93-99
32. Bryson, J. W., Betz, S. F., Lu, H. S., Suich, D. J., Zhou, H. X., O'Neil, K. T., and DeGrado, W. F. (1995) Science 270, 935-941
33. Zhang, Y., Chen, J., and Wang, J. (2008) Biomol. NMR Assign. 2, 207-210
34. Zhang, Y., Vasudevan, S., Sojitrawala, R., Zhao, W., Cui, C., Xu, C., Fan, D., Newhouse, Y., Balestra, R., Jerome, W. G., Weisgraber, K., Li, Q., and Wang, J. (2007) Biochemistry 46, 10722-10732
35. Segelke, B. W., Forstner, M., Knapp, M., Trakhanov, S. D., Parkin, S., Newhouse, Y. M., Bellamy, H. D., Weisgraber, K. H., and Rupp, B. (2000) Protein Sci. 9, 886-897
36. Redmond, K. A., Murphy, C., Narayanaswami, V., Kiss, R. S., Hauser, P., Guigard, E., Kay, C. M., and Ryan, R. O. (2006) FEBS J. 273, 558-567
37. Ruiz, J., Kouiavskaia, D., Migliorini, M., Robinson, S., Saenko, E. L., Gorlatova, N., Li, D., Lawrence, D., Hyman, B. T., Weisgraber, K. H., and Strickland, D. K. (2005) J. Lipid Res. 46, 1721-1731
38. Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M. S., Goldstein, J. L., and Deisenhofer, J. (2002) Science 298, 2353-2358
39. Fisher, C., Beglova, N., and Blacklow, S. C. (2006) Mol. Cell 22, 277-283