Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S

Journal of Biological Chemistry

Volumn 284, Issue 19, 2009, Pages 13004-13012

  Mitchell, Douglas A ^a,b   Lee, Shaun W ^a,b   Pence, Morgan A ^a   Markley, Andrew L ^a   Limm, Joyce D ^a   Nizet, Victor ^a   Dixon, Jack E ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL THERAPY; BIOSYNTHETIC ENZYMES; CHEMICAL STRUCTURE; CYTOLYTIC TOXIN; CYTOTOXIN; HUMAN PATHOGENS; POST-TRANSLATIONAL MODIFICATIONS; STREPTOCOCCUS PYOGENES; STREPTOLYSIN; STRUCTURAL INFORMATION; SUBSTRATE RECOGNITION;

BIOSYNTHESIS; SEMICONDUCTOR QUANTUM DOTS;

AMINES;

AGAR; STREPTOLYSIN S;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIUM TRANSFORMATION; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOLYSIS; ENZYME SPECIFICITY; GENE MUTATION; HEMOLYSIS; MOUSE; MUTATIONAL ANALYSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; STREPTOCOCCUS PYOGENES;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; MICE; MOLECULAR SEQUENCE DATA; OXAZOLES; PROLINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOCOCCUS PYOGENES; STREPTOLYSINS; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE; THIAZOLES; VIRULENCE;

STREPTOCOCCUS PYOGENES;

EID: 67649730080     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M900802200     Document Type: Article

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