Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease

Infection and Immunity

Volumn 70, Issue 10, 2002, Pages 5730-5739

  Fuller, Jeffrey D ^a   Camus, Alvin C ^a   Duncan, Carla L ^a   Nizet, Victor ^a   Bast, Darrin J ^a   Thune, Ronald L ^a   Low, Donald E ^a   De Azavedo, Joyce C S ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLYSIN; STREPTOLYSIN S; TRYPAN BLUE;

AMINO ACID SEQUENCE; ANIMAL MODEL; ARTICLE; BACTERIAL SKIN DISEASE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOSYNTHESIS; CONTROLLED STUDY; GENE CLUSTER; GENE IDENTIFICATION; GENE LOCUS; GENETIC COMPLEMENTATION; HEMOLYSIS; MOUSE; MUTAGENESIS; NONHUMAN; OPEN READING FRAME; OPERON; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; STREPTOCOCCUS GROUP A; STREPTOCOCCUS INIAE; TRANSPOSON;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; CHROMOSOME MAPPING; DISEASE MODELS, ANIMAL; DNA, BACTERIAL; FEMALE; FISHES; GENE EXPRESSION; GENES, BACTERIAL; HEMOLYSIS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS, INSERTIONAL; PHAGOCYTOSIS; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS; STREPTOLYSINS; VIRULENCE;

EID: 0036785660     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.10.5730-5739.2002     Document Type: Article

References (50)

1. Basic local alignment search tool
2. Group A streptococcal rofA gene is involved in the control of several virulence genes and eukaryotic cell attachment and internalization
3. Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae
4. Reduced virulence of group A streptococcal Tng16 mutants that do not produce streptolysin S
5. A rapid alkaline extraction procedure for screening recombinant plasmid DNA
6. Generation and surface localization of intact M protein in Streptococcus pyogenes are dependent on sagA
7. Cloning, nucleotide sequence, and expression of the nitroreductase gene from Enterobacter cloacae
8. Blue/white screening of recombinant plasmids in Gram-positive bacteria by interruption of alkaline phosphatase gene (phoZ) expression
9. Construction and evaluation of new drug-resistance cassettes for gene disruption mutagenesis in Streptococcus pneumoniae, using an ami test platform
10. Antibodies against a synthetic peptide of SagA neutralize the cytolytic activity of streptolysin S from group A streptococci
11. High efficiency transformation of Escherichia coli by high voltage electroporation
12. Streptococcus shiloi and Streptococcus difficile: Two new streptococcal species causing a meningoencephalitis in fish
13. Streptococcus shiloi, the name for an agent causing septicemic infection in fish, is a junior synonym of Streptococcus iniae
14. A response regulator that represses transcription of several virulence operons in the group A streptococcus
15. Characterization of the haemolytic activity of Streptococcus equi
16. Constitutive expression of fibronectin binding in Streptococcus pyogenes as a result of anaerobic activation of rofA
17. The identification of rofA, a positive-acting regulatory component of prtF expression: Use of an m gamma delta-based shuttle mutagenesis strategy in Streptococcus pyogenes
18. New genetic techniques for group B streptococci: High-efficiency transformation, maintenance of temperature-sensitive pWV01 plasmids, and mutagenesis with Tn917
19. Streptococcus iniae virulence is associated with a distinct genetic profile
20. DNA sequence, products, and transcriptional pattern of the genes involved in production of the DNA replication inhibitor microcin B17
21. Streptolysin S
22. Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants
23. Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: Preliminary characterization of mutants displaying acid sensitivity and nutritional requirements
24. Crystal structure of NADH oxidase from Thermus thermophilus
25. Streptolysin S and necrotising infections produced by group G streptococcus
26. Single-primer PCR procedure for rapid identification of transposon insertion sites
27. Cloning and expression in Escherichia coli of the streptolysin O determinant from Streptococcus pyogenes: Characterization of the cloned streptolysin O determinant and demonstration of the absence of substantial homology with determinants of other thiol-activated toxins
28. Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis
29. Current knowledge of the type-specific M antigens of group A streptococci
30. PCR ligation mutagenesis in transformable streptococci: Application and efficiency
31. From peptide precursors to oxazole and thiazole-containing peptide antibiotics: Microcin B17 synthase
32. Identification of pel, a Streptococcus pyogenes locus that affects both surface and secreted proteins
33. Role of streptolysin O in a mouse model of invasive group A streptococcal disease
34. Insertional inactivation of streptolysin S expression is associated with altered riboflavin metabolism in Streptococcus pyogenes
35. New thermosensitive plasmid for gram-positive bacteria
36. Cofactor requirements and reconstitution of microcin B17 synthetase: A multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17
37. The role played by the group A streptococcal negative regulator Nra on bacterial interactions with epithelial cells
38. Genetic locus for streptolysin S production by group A streptococcus
39. Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum
40. 2-forming NADH oxidase from the extreme thermophilic Thermus thermophilus HB8 and its expression in Escherichia coli
41. Streptococcus iniae associated with mortality of Tilapia nilotica x T. aurea hybrids
42. Streptococcus iniae sp. nov., a betahemolytic streptococcus isolated from an Amazon freshwater dolphin, Inia geoffrensis
43. Genetic basis for the beta-haemolytic/cytolytic activity of group B Streptococcus
44. Electrotransformation of Streptococcus pyogenes with plasmid and linear DNA
45. Identification of genetic determinants for the hemolytic activity of Streptococcus agalactiae by ISS1 transposition
46. A simple procedure for isolation of cloning vectors and endogenous plasmids from viridans group streptococci and Staphylococcus aureus
47. Purification and characterization of wild-type and mutant "classical" nitroreductases of Salmonella typhimurium. L33R mutation greatly diminishes binding of FMN to the nitroreductase of S. typhimurium
48. Invasive infections due to a fish pathogen, Streptococcus iniae
49. Evaluation of the role of hemolysin and pigment in the pathogenesis of early onset group B streptococcal infection
50. Host/vector interactions which affect the viability of recombinant phage lambda clones