Apnea of Prematurity, Sudden Infant Death Syndrome, and Apparent Life-Threatening Events

Pediatric Respiratory Medicine

Volumn , Issue , 2008, Pages 413-434

  Poets, Christian F ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 67649671320     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-032304048-8.50034-7     Document Type: Chapter

References (345)

1. American Academy of Pediatrics Task Force on Sudden Infant Death Syndrome (2005) The changing concept of sudden infant death syndrome: Diagnostic coding shifts, controversies regarding the sleeping environment, and new variables to consider in reducing risk. Pediatrics 116 1245-1255.
2. RG Carpenter, LM Irgens, PS Blair, et al. (2004) Sudden unexplained infant death in 20 regions in Europe: Case control study. Lancet 363 185-191.
3. CE Hunt, MJ Corwin, T Baird, et al. (2004) Collaborative Home Infant Monitoring Evaluation study group. Cardiorespiratory events detected by home memory monitoring and one-year neurodevelopmental outcome. J Pediatr 145 465-471.
4. A Kahn (2004) European Society for the Study and Prevention of Infant Death. Recommended clinical evaluation of infants with an apparent life-threatening event. Consensus document of the European Society for the Study and Prevention of Infant Death, 2003. Eur J Pediatr 163 108-115.
5. A Khan, M Qurashi, K Kwiatkowski, et al. (2005) Measurement of the CO 2 apneic threshold in newborn infants: Possible relevance for periodic breathing and apnea. J Appl Physiol 98 1171-1176.
6. HC Kinney (2005) Abnormalities of the brainstem serotonergic system in the sudden infant death syndrome. A review. Pediatr Dev Pathol 5 507-524.
7. RJ Martin, JM DiFiore, RL Davis, et al. (1998) Persistence of the biphasic ventilatory response to hypoxia in preterm infants. J Pediatr 132 960-964.
8. SH Opdal and TO Rognum (2004) The sudden infant death syndrome gene: Does it exist? Pediatrics 114 e506-e512.
9. CF Poets (2003) Pathophysiology of apnea of prematurity: implications from observational studies. OP Mathew (Eds) Respiratory Control and Its Disorders in the Newborn New York: Dekker 295-316.
10. CF Poets (2001) The role of monitoring. RW Byard, HF Krous (Eds) Sudden Infant Death Syndrome—Problems, Progress and Possibilities London: Arnold 236-242.
11. B Schmidt, RS Roberts, P Davis, et al. (2006) Caffeine therapy for apnea of prematurity. N Engl J Med 354 2112-2121.
12. B Schmidt (1999) Methylxanthine therapy in premature infants: Sound practice, disaster, or fruitless byway? J Pediatr 135 526-528.
13. DJ Henderson-Smart (1981) The effect of gestational age on the incidence and duration of recurrent apnoea in newborn babies. Aust Paediatr J 17 273-276.
14. DI Tudehope, YM Rogers, YR Burns, et al. (1986) Apnoea in very low birthweight infants: Outcome at 2 years. Aust Paediatr J 22 131-134.
15. GA Levitt, A Mushin, S Bellman and DR Harvey (1988) Outcome of preterm infants who suffered neonatal apnoeic attacks. Early Hum Dev 16 235-243.
16. A Janvier (2004) Apnea is associated with neurodevelopmental impairment in very low birth weight infants. J Perinatol 24 763-768.
17. AH Koons, N Mojica, N Jadeja, et al. (1993) Neurodevelopmental outcome of infants with apnea of infancy. Am J Perinatol 10 208-211.
18. PY Cheung, KJ Barrington, NN Finer and CM Robertson (1999) Early childhood neurodevelopment in very low birth weight infants with predischarge apnea. Pediatr Pulmonol 27 14-20.
19. CE Hunt, MJ Corwin, T Baird, et al. (2004) Collaborative Home Infant Monitoring Evaluation study group. Cardiorespiratory events detected by home memory monitoring and one-year neurodevelopmental outcome. J Pediatr 145 465-471.
20. PG Davis, LW Doyle, AL Rickards, et al. (2000) Methylxanthines and sensorineural outcome at 14 years in children <1501 g birthweight. J Paediatr Child Health 36 47-50.
21. C Sreenan, PC Etches, N Demianczuk and CM Robertson (2001) Isolated mental developmental delay in very low birth weight infants: Association with prolonged doxapram therapy for apnea. J Pediatr 139 832-837.
22. C Poets, P Bartmann and P Groneck Vorstand der Gesellschaft für Neonatologie und Pädiatrische Intensivmedizin. Therapie der idiopathischen Apnoe-Anfälle bei Frühgeborenen. http://www.leitlinien.net
23. CF Poets and DP Southall (1991) Patterns of oxygenation during periodic breathing in preterm infants. Early Hum Dev 26 1-12.
24. DJ Girling (1972) Changes in heart rate, blood pressure, and pulse pressure during apnoeic attacks in newborn babies. Arch Dis Child 47 405-410.
25. CN Storrs (1977) Cardiovascular effects of apnoea in preterm infants. Arch Dis Child 52 534-540.
26. M Gabriel and M Albani (1976) Cardiac slowing and respiratory arrest in preterm infants. Eur J Pediatr 122 257-261.
27. H Vyas, AD Milner and IE Hopkin (1981) Relationship between apnoea and bradycardia in preterm infants. Acta Paediatr Scand 70 785-790.
28. CF Poets, VA Stebbens, MP Samuels and DP Southall (1993) The relationship between episodes of bradycardia, apnea and hypoxemia in preterm infants. Pediatr Res 34 144-147.
29. D.M. de B Daly M (1986) Interactions between respiration and circulation. AP Fishman (Eds) Handbook of Physiology, Section 3, Vol 2, Part 1 Bethesda, Md: American Physiological Society 529-594. 198
30. JE Angell-James and B Daly M de (1969) Cardiovascular responses in apnoeic asphyxia: Role of arterial chemoreceptors and the modification of their effects by a pulmonary vagal inflation relfex. J Physiol 201 87-104.
31. NN Finer, KJ Barrington, BJ Hayes and A Hugh (1992) Obstructive, mixed, and central apnea in the neonate: Physiologic correlates. J Pediatr 121 943-950.
32. JA Adams, IA Zabaleta and MA Sackner (1997) Hypoxemic events in spontaneously breathing premature infants: Etiologic basis. Pediatr Res 42 463-471.
33. A Olinsky, MH Bryan and AC Bryan (1974) Influence of lung inflation on respiratory control in neonates. J Appl Physiol 36 426-429.
34. Agostoni E, Mead J: Statics of the respiratory system. In Fishman AP (ed): Handbook of Physiology. Respiration. Am Physiol Soc Washington 3(1):387-409, 1965.
35. PC Kosch and AR Stark (1984) Dynamic maintenance of end-expiratory lung volume in full-term infants. J Appl Physiol: Respirat Environ Exercise Physiol 57 1126-1133.
36. AH Numa and CJL Newth (1996) Anatomic dead space in infants and children. J Appl Physiol 80 1485-1489.
37. AR Stark, BA Cohlan, TB Waggener, et al. (1987) Regulation of end-expiratory lung volume during sleep in premature infants. J Appl Physiol 62 1117-1123.
38. CF Poets, GA Rau, K Neuber, et al. (1997) Determinants of lung volume in spontaneously breathing preterm infants. Am J Respir Crit Care Med 155 649-653.
39. GM Davis and J Moscato (1994) Changes in lung mechanics following sighs in premature newborns without lung disease. Pediatr Pulmonol 17 26-30.
40. BT Thach and HW Taeusch (1976) Sighing in newborn human infants: Role of inflation-augmenting reflex. J Appl Physiol 41 502-507.
41. DJ Henderson-Smart (1980) Vulnerability to hypoxaemia in the newborn. Sleep 3 331-342.
42. LJ Findley, AL Ries, GM Tisi and PD Wagner (1983) Hypoxemia during apnea in normal subjects: Mechanisms and impact of lung volume. J Appl Physiol: Respirat Environ Exercise Physiol 55 1777-1783.
43. MH Wilkinson, PJ Berger, N Blanch and V Brodecky (1995) Effect of venous oxygenation on arterial desaturation rate during repetitive apneas in lambs. Respir Physiol 101 321-331.
44. S Hannam, DM Ingram and AD Milner (1998) A possible role for the Hering-Breuer deflation reflex in apnea of prematurity. J Pediatr 132 35-39.
45. BD Speidel and PM Dunn (1976) Use of nasal continuous positive airway pressure to treat severe recurrent apnoea in very preterm infants. Lancet 2 658-660.
46. DW Thibeault, MM Wong and PAM Auld (1967) Thoracic gas volume changes in premature infants. Pediatrics 40 403-411.
47. J Kattwinkel, HS Nearman, AA Fanaroff, et al. (1975) Apnea of prematurity. Comparative effects of cutaneous stimulation and nasal continuous positive pressure ventilation. J Pediatr 86 588-592.
48. H Bakwin (1923) Oxygen therapy in premature babies with anoxemia. Am J Dis Child 25 157-162.
49. S Phillips (1936) Cyanosis in infancy. J Arkansas Med Soc 33 99-102.
50. M Garg, SI Kurzner, DB Bautista and TG Keens (1988) Clinically unsuspected hypoxia during sleep and feeding in infants with bronchopulmonary dysplasia. Pediatrics 81 635-642.
51. L Singer, RJ Martin, SW Hawkins, et al. (1992) Oxygen desaturation complicates feeding in infants with bronchopulmonary dysplasia after discharge. Pediatrics 90 380-384.
52. C Guilleminault and S Coons (1984) Apnea and bradycardia during feeding in infants weighing >2000 gm. J Pediatr 104 932-935.
53. CL Rosen, DG Glaze and JD Frost (1984) Hypoxemia associated with feeding in the preterm infant and full-term neonate. Am J Dis Child 138 623-628.
54. CR Shivpuri, RJ Martin, WA Carlo and AA Fanaroff (1983) Decreased ventilation in preterm infants during oral feeding. J Pediatr 103 285-289.
55. A Wilkinson and VYH Yu (1974) Immediate effects of feeding on blood-gases and some cardiorespiratory functions in ill newborn infants. Lancet 1 1083-1085.
56. BD Patel, R Dinwiddie, SP Kumar and WW Fox (1977) The effects of feeding on arterial blood gases and lung mechanics in newborn infants recovering from respiratory disease. J Pediatr 90 435-438.
57. O Blondheim, S Abbasi, WW Fox and VK Bhutani (1993) Effect of enteral gavage feeding rate on pulmonary functions of very low birth weight infants. J Pediatr 122 751-755.
58. GP Heldt (1988) The effect of gavage feeding on the mechanics of the lung, chest wall, and diaphragm of preterm infants. Pediatr Res 24 55-58.
59. OP Mathew (1988) Respiratory control during nipple feeding in preterm infants. Pediatr Pulmonol 5 220-224.
60. AM Davies, JS Koenig and BT Thach (1989) Characteristics of upper airway chemoreflex prolonged apnea in human infants. Am Rev Respir Dis 139 668-673.
61. JM Lopes, NL Muller, MH Bryan and AC Bryan (1981) Synergistic behavior of inspiratory muscles after diaphragmatic fatigue in the newborn. J Appl Physiol 51 547-551.
62. CF Poets, M Langner and B Bohnhorst (1997) Effects of nipple feeding and 2 different methods of gavage feeding on oxygenation in preterm infants. Acta Paediatr 86 419-423.
63. AK Ewer, GM Durbin, MEI Morgan and IW Booth (1994) Gastric emptying in preterm infants. Arch Dis Child 71 F24-F27.
64. JJ Herbst, SD Minton and LS Book (1979) Gastroesophageal reflux causing respiratory distress and apnea in newborn infants. J Pediatr 95 763-768.
65. AP Menon, GL Schefft and BT Thach (1985) Apnea associated with regurgitation in infants. J Pediatr 106 625-629.
66. CS Peter, N Sprodowski and B Bohnhorst (2002) Gastroesophgeal reflux and apnea of prematurity: No temporal relationship. Pediatrics 109 8-11.
67. JM Di Fiore, M Arko, M Whitehouse, et al. (2005) Apnea is not prolonged by acid gastroesophageal reflux in preterm infants. Pediatrics 116 1059-1063.
68. RM Ward, JA Lemons and RA Molteni (1999) Cisapride: A survey of the frequency of use and adverse events in premature newborns. Pediatrics 103 469-472.
69. AN Krauss, J Brown, S Waldman, et al. (1978) Pulmonary function following feeding in low-birth-weight infants. Am J Dis Child 132 139-142.
70. GP Heldt (1988) Development of stability of the respiratory system in preterm infants. J Appl Physiol 65 441-444.
71. HC Miller, FC Behrle and NW Smull (1959) Severe apnea and irregular respiratory rhythms among premature infants. Pediatrics 23 676-685.
72. NA Calder, BA Williams, P Kumar and MA Hanson (1994) The respiratory response of healthy term infants to breath-by-breath alternations in inspired oxygen at two postnatal ages. Pediatr Res 35 321-324.
73. A Fenner, U Schalk, H Hoenicke, et al. (1973) Periodic breathing in premature and neonatal babies: Incidence, breathing pattern, respiratory gas tensions, response to changes in the composition of ambient air. Pediatr Res 7 174-183.
74. D Richard, CF Poets, S Neale, et al. (1993) Arterial oxygen saturation in preterm neonates without respiratory failure. J Pediatr 123 963-968.
75. CF Poets (2003) Pathophysiology of apnea of prematurity: implications from observational studies. OP Mathew (Eds) Respiratory Control and Its Disorders in the Newborn New York: Dekker 295-316.
76. R Knill and AC Bryan (1976) An intercostal-phrenic inhibitory reflex in human newborn infants. J Appl Physiol 40 352-356.
77. R Knill, W Andrews, AC Bryan and MH Bryan (1976) Respiratory load compensation in infants. J Appl Physiol 40 357-361.
78. AD Milner, AW Boon, RA Saunders and IE Hopkin (1980) Upper airway obstruction and apnoea in preterm babies. Arch Dis Child 55 22-25.
79. RP Lemke, N Idiong, S Al-Saedi, et al. (1998) Evidence of a critical period of airway instability during central apneas in preterm infants. Am J Respir Crit Care Med 157 470-474.
80. S Renolleau, P Letourneau, T Niyonsenga and JP Praud (1999) Thyroarytenoid muscle electrical activity during spontaneous apneas in preterm lambs. Am J Respir Crit Care Med 159 1396-1404.
81. I Klanicka, V Diaz, D Dorion and JP Praud (1998) Coordination between glottic adductor muscle and diaphragm EMG activity in the fetal lamb in utero. J Appl Physiol 84 1560-1565.
82. NR Ruggins and AD Milner (1991) Site of upper airway obstruction in preterm infants with problematical apnoea. Arch Dis Child 66 787-792.
83. NR Ruggins and AD Milner (1993) Site of upper airway obstruction in infants following an acute life-threatening event. Pediatrics 91 595-601.
84. CJ Upton, AD Milner and GM Stokes (1992) Response to external obstruction in preterm infants with apnea. Pediatr Pulmonol 14 233-238.
85. YK Abu-Osba, OP Mathew and BT Thach (1981) An animal model for airway sensory deprivation producing obstructive apnea with postmortem findings of sudden infant death syndrome. Pediatrics 68 796-801.
86. TB Waggener, ID Frantz, BA Cohlan and AR Stark (1989) Mixed and obstructive apneas are related to ventilatory oscillations in premature infants. J Appl Physiol 66 2818-2826.
87. OP Mathew (1985) Maintenance of upper airway patency. J Pediatr 106 863-869.
88. RA Mitchell, DA Herbert and DG Baker (1985) Inspiratory rhythm in airway smooth muscle tone. J Appl Physiol 58 911-920.
89. NJ Eastman (1936) Fetal blood studies. Am J Obstetr Gynecol 563-572.
90. H Rigatto, JP Brady and R de la Torre Verduzco (1975) Chemoreceptor reflexes in preterm infants: I. The effect of gestational and postnatal age on the ventilatory response to inhalation of 100% and 15% oxygen. Pediatrics 55 604-613.
91. RJ Martin, JM DiFiore, RL Davis, et al. (1998) Persistence of the biphasic ventilatory response to hypoxia in preterm infants. J Pediatr 132 960-964.
92. ML Nock, JM Di Fiore, MK Arko and RJ Martin (2004) Relationship of the ventilatory response to hypoxia with neonatal apnea in preterm infants. J Pediatr 144 291-295.
93. H Lagercrantz, H Ahlström, B Jonson, et al. (1978) A critical oxygen level below which irregular breathing occurs in preterm infants. C von Euler, H Lagercrantz (Eds) Central Nervous Control Mechanisms in Breathing Oxford: Pergamon 161-164.
94. Z Weintraub, R Alvaro, K Kwiatkowski, et al. (1992) Effects of inhaled oxygen (up to 40%) on periodic breathing and apnea in preterm infants. J Appl Physiol 72 116-120.
95. SP Bessman and CL Carpenter (1985) The creatine-creatine phosphate energy shuttle. Annual Rev Biochem 54 831-862.
96. C Pierard, J Champagnat, M Denavit-Saubie, et al. (1995) Brain stem energy metabolism response to acute hypoxia in anaesthetized rats: A 31P NMR study. Neuro Report 7 281-285.
97. R Lolley, W Balfour and F Samson (1961) The high energy phosphates in developing brain. J Neurochem 7 289-297.
98. PD Balsom, K Söderlund and B Ekblom (1994) Creatine in humans with special reference to creatine supplementation. Sports Med 18 268-280.
99. PL Greenhaff, A Casey, AH Short, et al. (1993) Influence of oral creatine supplementation on muscle tone during repeated bouts of maximal voluntary exercise in man. Clin Sci 84 565-571.
100. K Sahlin, M Tonkonogi and K Soderlund (1998) Energy supply and muscle fatigue in humans. Acta Physiol Scand 162 261-266.
101. B Wilken, JM Ramirez, I Probst, et al. (2000) Anoxic ATP depletion in neonatal brainstem is prevented by creatine supplementation. Arch Dis Child Fetal Neonatal Ed 82 F224-F227.
102. B Wilken, JM Ramirez, DW Richter and F Hanefeld (1998) Supplemental creatine enhances hypoxic augmentation in vivo by preventing ATP depletion (abstract). Eur J Pediatr 157 178.
103. A Khan, M Qurashi, K Kwiatkowski, et al. (2005) Measurement of the CO 2 apneic threshold in newborn infants: Possible relevance for periodic breathing and apnea. J Appl Physiol 98 1171-1176.
104. S Al-Aif, R Alvaro, J Manfreda, et al. (2001) Inhalation of low (0.5%-1.5%) CO 2 as a potential treatment for apnea of prematurity. Semin Perinatol 25 100-106.
105. NN Finer, R Higgins, J Kattwinkel and RJ Martin (2006) Summary of proceedings from the Apnea-of-Prematurity group. Pediatrics 117 547-551.
106. RJ Martin, N Herrell, D Rubin and A Fanaroff (1979) Effect of supine and prone positions on arterial oxygen tension in the preterm infant. Pediatrics 63 528-531.
107. LO Kurlak, NR Ruggins and TJ Stephenson (1994) Effect of nursing position on incidence, type, and duration of clinically significant apnoea in preterm infants. Arch Dis Child Fetal Neonatal Ed 71 F16-F19.
108. R Heimler, J Langlois, DJ Hodel, et al. (1992) Effect of positioning on the breathing pattern of preterm infants. Arch Dis Child 67 312-314.
109. TM Baird, JB Paton and DE Fisher (1991) Improved oxygenation with prone positioning in neonates: Stability of increased transcutaneous PO 2. J Perinatol 11 315-318.
110. OG Jenni, K von Siebenthal, M Wolf, et al. (1997) Effect of nursing in the head elevated tilt position (15 degrees) on the incidence of bradycardic and hypoxemic episodes in preterm infants. Pediatrics 100 622-625.
111. A Bauschatz, C Kaufmann, D Haensse, et al. (2006) Effect of nursing in the “Three-Stair-Position” according to kinaesthetic infant handling on the incidence of apnea episodes in preterm infants. Z Geburtsh Neonatol 210 S60.
112. J Stocks (1980) Effect of nasogastric tubes on nasal resistance in infancy. Arch Dis Child 55 17-21.
113. V van Someren, SJ Linnett, JK Stothers and PG Sullivan (1984) An investigation into the benefits of resiting nasoenteric feeding tubes. Pediatrics 74 379-383.
114. PG Davis and DJ Henderson-Smart (2003) Nasal continuous positive airways pressure immediately after extubation for preventing morbidity in preterm infants. Cochrane Database Syst Rev CD000143.
115. PB Pandit, SE Courtney, KH Pyon, et al. (2001) Work of breathing during constant- and variable-flow nasal continuous positive airway pressure in preterm neonates. Pediatrics 108 682-685.
116. MJ Miller, WA Carlo and RJ Martin (1985) Continuous positive airway pressure selectively reduces obstructive apnea in preterm infants. J Pediatr 106 91-94.
117. AG De Paoli, PG Davis, B Faber and CJ Morley (2002) Devices and pressure sources for administration of nasal continuous positive airway pressure (NCPAP) in preterm neonates. Cochrane Database Syst Rev CD002977.
118. B Lemyre, PG Davis and AG De Paoli (2000) Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for apnea of prematurity. Cochrane Database Syst Rev CD002272.
119. AG De Paoli, C Morley and PG Davis (2003) Nasal CPAP for neonates: what do we know in 2003? Arch Dis Child Fetal Neonatal Ed 88 F168-F172.
120. N Simakajornboon, RC Beckerman, C Mack, et al. (2002) Effect of supplemental oxygen on sleep architecture and cardiorespiratory events in preterm infants. Pediatrics 110 884-888.
121. H Rigatto (1977) Apnea and periodic breathing. Semin Perinatol 1 375-381.
122. LM Askie, DJ Henderson-Smart, L Irwig and JM Simpson (2003) Oxygen-saturation targets and outcomes in extremely preterm infants. N Engl J Med 349 959-967.
123. CA Pohl, M Epstein, D Kaplon and E Gibson (1998) Role of a screening hematocrit for pathologic apnea and bradycardia in healthy preterm infants. Pediatr Pulmonol 26 445.
124. CF Poets, MP Samuels, CAJ Wardrop, et al. (1992) Reduced haemoglobin levels in infants presenting with apparent life-threatening events—a retrospective investigation. Acta Paediatr 81 319-321.
125. EM Bifano, F Smith and J Borer (1992) Relationship between determinants of oxygen delivery and respiratory abnormalities in preterm infants with anemia. J Pediatr 120 292-296.
126. JG DeMaio, MC Harris, C Deuber and AR Spitzer (1989) Effect of blood transfusion on apnea frequency in growing premature infants. J Pediatr 114 1039-1041.
127. A Joshi, T Gerhardt, P Shandloff and E Bancalari (1987) Blood transfusion effect on the respiratory pattern of preterm infants. Pediatrics 80 79-84.
128. P Sasidharan and R Heimler (1992) Transfusion induced changes in the breathing patterns of healthy preterm anemic infants. Pediatr Pulmonol 12 170-173.
129. H Stute, B Greiner and O Linderkamp (1995) Effect of blood transfusion on cardiorespiratory abnormalities in preterm infants. Arch Dis Child 72 F194-F196.
130. JP Blank, TG Sheagren, J Vajaria, et al. (1984) The role of RBC transfusion in the premature infant. Am J Dis Child 138 831-833.
131. WG Keyes, PK Donohue, JL Spivak, et al. (1989) Assessing the need for transfusion of premature infants and role of hematocrit, clinical signs, and erythropoietin level. Pediatrics 84 412-417.
132. J Meyer, A Sive and P Jacobs (1993) Empiric red cell transfusion in asymptomatic preterm infants. Acta Paediatr 82 30-34.
133. CF Poets, U Pauls and B Bohnhorst (1997) Effect of blood transfusion on apnea, bradycardia and hypoxemia in preterm infants. Eur J Pediatr 156 311-316.
134. E Westkamp, V Soditt, S Adrian, et al. (2002) Blood transfusion in anemic infants with apnea of prematurity. Biol NeonNeon 82 228-232.
135. EF Bell, RG Strauss, JA Widness, et al. (2005) Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants. Pediatrics 115 1685-1691.
136. V Bhatt-Mehta and RE Schumacher (2003) Treatment of apnea of prematurity. Paediatr Drugs 5 195-210.
137. JEM Scanlon, KC Chin, MEI Morgan, et al. (1992) Caffeine or theophylline for neonatal apnoea? Arch Dis Child 67 425-428.
138. HU Bucher and G Duc (1988) Does caffeine prevent hypoxaemic episodes in premature infants? Eur J Pediatr 147 288-291.
139. B Schmidt, RS Roberts, P Davis, et al. (2006) Caffeine therapy for apnea of prematurity. N Engl J Med 354 2112-2121.
140. Schmidt B, Roberts R, Davis P: The International Caffeine for Apnea of Prematurity (CAP) trial: Preliminory analysis of outcomes at a corrected age of 18 to 21 months. Abstract presented at the Pediatric Academic Societies Annual Meeting, Toronto, May 5-8, 2007.
141. KJ Barrington, NN Finer, KL Peters and J Barton (1986) Physiologic effects of doxapram in idiopathic apnea of prematurity. J Pediatr 108 125-129.
142. KJ Barrington, NN Finer, G Torok-Both, et al. (1987) Dose-response relationship of doxapram in the therapy for refractory apnea of prematurity. Pediatrics 80 22-27.
143. F Hayakawa, S Hakamada, K Kuno, et al. (1986) Doxapram in the treatment of idiopathic apnea of prematurity: Desirable dosage and serum concentrations. J Pediatr 109 138-140.
144. CF Poets, S Darraj and B Bohnhorst (1999) Effect of doxapram on episodes of apnoea, bradycardia and hypoxaemia in preterm infants. Biol Neon 76 207-213.
145. MG Romeo, P Betta, LG Tina, et al. (1995) Oral administration of doxapram in preterm neonates with aminophylline-resistant apnea crisis. Pediatr Med Chir 17 123-126.
146. J Tay-Uyboco, K Kwiatkowski, DB Cates, et al. (1991) Clinical and physiological responses to prolonged nasogastric administration of doxapram for apnea of prematurity. Biol Neonate 59 190-200.
147. A Bairam, L Akramoff-Gershan, K Beharry, et al. (1991) Gastrointestinal absorption of doxapram in neonates. Am J Perinatol 8 110-113.
148. B Bohnhorst, T Geuting, CS Peter, et al. (2004) Randomized controlled trial of oral creatine supplementation (not effective) for apnea of prematurity. Pediatrics 113 e302-e306.
149. S Blazer, GT Reinersman, J Askanazi, et al. (1994) Branched-chain amino acids and respiratory pattern and function in the neonate. J Perinatol 14 290-295.
150. DJ Henderson-Smart and DA Osborn (2002) Kinesthetic stimulation for preventing apnea in preterm infants. Cochrane Database Syst Rev 2 CD000373.
151. MP Sammon and RA Darnall (1994) Entrainment of respiration to rocking in premature infants: Coherence analysis. J Appl Physiol 77 1548-1554.
152. L Marlier, B Schaal, C Gaugler and J Messer (2001) Olfaction in premature human newborns: Detection and discrimination abilities two months before gestational term. Chemical Signals Vertebr 9 205-209.
153. L Marlier, C Gaugler and J Messer (2005) Olfactory stimulation prevents apnea in premature newborns. Pediatrics 115 83-88.
154. DJ Henderson-Smart, AG Pettigrew and DJ Campbell (1983) Clinical apnea and brain-stem neural function in preterm infants. N Engl J Med 308 353-357.
155. CJ Upton, AD Milner and GM Stokes (1992) Response to tube breathing in preterm infants with apnea. Pediatr Pulmonol 12 23-28.
156. Sudhoff K: Internationale Hygiene Ausstellung Dresden. Dresden Katalog, 1911, Item 6375, p 292.
157. Allgemeines Gesetzbuch für die preussischen Staaten. Elfter Abschnitt—von den körperlichen Verletzungen Berlin: Königliche Hofbuchdruckerey 1282.
158. SW Fearn (1834) Sudden and unexplained death of children. Lancet 246.
159. A Paltauf (1889) Ueber die Beziehungen der Thymus zum plötzlichen Tod. Wiener klin Wchenschr 2 877-881. and 3:172-175, 1890.
160. CF Poets (1996) Status thymico-lymphaticus, apnoea, and sudden infant death—lessons learned from the past? Eur J Pediatr 155 165-167.
161. AB Bergman, JB Beckwith and GC Ray (Eds) (1970) Sudden infant death syndrome: Proceedings of the Second International Conference on Causes of Sudden Death in Infants Seattle: University of Washington Press 17-18.
162. J Huber (1993) Sudden infant death syndrome: The new clothes of the emperor. Eur J Pediatr 152 93-94.
163. HF Krous, JB Beckwith, RW Byard, et al. (2004) Sudden infant death syndrome and unclassified sudden infant deaths: A definitional and diagnostic approach. Pediatrics 114 234-238.
164. National Institutes of Health consensus development conference on infantile apnea and home monitoring, Sept 29 to Oct 1, 1986. Pediatrics 79 292-299.
165. MH Malloy and DH Freeman (2004) Age at death, season, and day of death as indicators of the effect of the back to sleep program on sudden infant death syndrome in the United States, 1992-1999. Arch Pediatr Adolesc Med 158 359-365.
166. K Helweg-Larsen, LB Knudsen, M Gregersen and J Simonsen (1992) Sudden infant death syndrome in Denmark: Evaluation of the increasing incidence of registered SIDS in the period 1972 to 1983 and results of a prospective study in 1987 through 1988. Pediatrics 89 855-859.
167. GA De Jonge, AC Engelberts, AJP Koomen-Liefting and PJ Kostense (1989) Cot death and prone sleeping position in The Netherlands. BMJ 298 722.
168. AC Engelberts, GA de Jonge and PJ Kostense (1991) An analysis of trends in the incidence of sudden infant death in The Netherlands 1969-89. J Paediatr Child Health 27 329-333.
169. MH Malloy and M MacDorman (2005) Changes in the classification of sudden unexpected infant deaths: United States, 1992-2001. Pediatrics 115 1247-1253.
170. AL Ponsonby, T Dwyer and J Cochrane (2002) Population trends in sudden infant death syndrome. Semin Perinatol 26 296-305.
171. D Kyle, R Sunderland, M Stonehouse, et al. (1990) Ethnic differences in incidence of sudden infant death syndrome in Birmingham. Arch Dis Child 65 830-833.
172. EA Mitchell, AW Stewart, R Scragg, et al. (1993) Ethnic differences in mortality from sudden infant death syndrome in New Zealand. BMJ 306 13-16.
173. L Black, RJ David, RT Brouillette and CE Hunt (1986) Effects of birth weight and ethnicity on incidence of sudden infant death syndrome. J Pediatr 108 209-214.
174. JF Kraus, S Greenland and M Bulterys (1989) Risk factors for sudden infant death syndrome in the US collaborative perinatal project. Int J Epidemiol 18 113-120.
175. FR Hauck, CM Moore, SM Herman, et al. (2002) The contribution of prone sleeping position to the racial disparity in sudden infant death syndrome: The Chicago Infant Mortality Study. Pediatrics 110 772-780.
176. EJ Adams, GF Chavez, D Steen, et al. (1998) Changes in the epidemiologic profile of sudden infant death syndrome as rates decline among California infants: 1990-1995. Pediatrics 102 1445-1451.
177. JK Grether, JS Schulman and LA Croen (1989) Sudden infant death syndrome and birth weight. J Pediatr 114 561-567.
178. S Polberger and NW Svenningsen (1985) Early neonatal sudden infant death and near death of fullterm infants in maternity wards. Acta Paediatr Scand 74 861-866.
179. J Rajs and F Hammarquist (1988) Sudden infant death in Stockholm. Acta Paediatr Scand 77 812-820.
180. WG Guntheroth (1989) Crib Death: The Sudden Infant Death Syndrome New York: Futura
181. AB Bergmann, CG Ray, MA Pomeroy, et al. (1972) Studies of the sudden infant death syndrome in King County, Washington. III. Epidemiology. Pediatrics 1972 49 860-870.
182. EC Uren, AL Williams, I Jack and JW Rees (1980) Association of respiratory virus infections with sudden infant death syndrome. Med J Aust 1 417-419.
183. A Nicoll and A Gardner (1988) Whooping cough and unrecognized postperinatal mortality. Arch Dis Child 63 41-47.
184. HJ Hoffman, JC Hunter, K Damus, et al. (1987) Diphtheria-tetanus-pertussis immunization and sudden infant death: Results of the National Institute of Child Health and Human Development cooperative epidemiological study of sudden infant death syndrome risk factors. Pediatrics 79 598-611.
185. EA Mitchell, AW Stewart and M Clements (1995) Immunisation and the sudden infant death syndrome. New Zealand Cot Death Study Group. Arch Dis Child 73 498-501.
186. PJ Fleming, PS Blair, MW Platt, et al. (2001) The UK accelerated immunisation programme and sudden unexpected death in infancy: Case-control study. BMJ 322 822.
187. CE Leach, PS Blair, PJ Fleming, et al. (1999) Epidemiology of SIDS and explained sudden infant deaths. CESDI SUDI Research Group. Pediatrics 104 e43.
188. EA Mitchell and AW Stewart (1988) Deaths from sudden infant death syndrome on public holidays and weekends. Aust NZ J Med 18 861-863.
189. JA Mooney, PJ Helms and IT Jolliffe (2004) Higher incidence of SIDS at weekends, especially in younger infants. Arch Dis Child 89 670-672.
190. EA Mitchell, KP Nelson, JMD Thompson, et al. (1994) Travel and changes in routine do not increase the risk of sudden infant death syndrome. Acta Paediatr 83 815-818.
191. WJ Kleemann, R Urban, J Eidam, et al. (1991) Die Auffindesituation beim plötzlichen Kindstod. Rechtsmedizin 1 147-151.
192. EA Mitchell, BJ Taylor, RPK Ford, et al. (1992) Four modifiable and other major risk factors for cot death: the New Zealand study. J Paediatr Child Health 28 S3-S8.
193. GM Buck, DL Cookfair, AM Michalek, et al. (1989) Intrauterine growth retardation and risk of sudden infant death syndrome. Am J Epidemiol 129 874-884.
194. HJ Hoffman, K Damus, L Hillman and E Krongrad (1998) Risk factors for SIDS: Results of the National Institute of Child Health and Human Development Cooperative Epidemiological Study. Ann N Y Acad Sci 533 13-20.
195. EA Mitchell, JMD Thompson, AW Stewart, et al. (1992) Postnatal depression and SIDS: A prospective study. J Paediatr Child Health 28 S13-S16.
196. D Getahun, D Amre, GG Rhoads and K Demissie (2004) Maternal and obstetric risk factors for sudden infant death syndrome in the United States. Obstet Gynecol 103 646-652.
197. RG Carpenter, LM Irgens, PS Blair, et al. (2004) Sudden unexplained infant death in 20 regions in Europe: Case control study. Lancet 363 185-191.
198. DS Chong, PS Yip and J Karlberg (2004) Maternal smoking: An increasing unique risk factor for sudden infant death syndrome in Sweden. Acta Paediatr 93 471-478.
199. EA Mitchell, RPK Ford, AW Stewart, et al. (1993) Smoking and the sudden infant death syndrome. Pediatrics 91 893-8906.
200. MG Bulterys, S Greenland and JF Kraus (1990) Chronic fetal hypoxia and sudden infant death syndrome: Interaction between maternal smoking and low hematocrit during pregnancy. Pediatrics 86 535-540.
201. JP Hanrahan, IB Tager, MR Segal, et al. (1992) The effect of maternal smoking during pregnancy on early infant lung function. Am Rev Respir Dis 145 1129-1135.
202. RS Horne, P Franco, TM Adamson, et al. (2004) Influences of maternal cigarette smoking on infant arousability. Early Hum Dev 79 49-58.
203. AL Wright, C Holberg, FD Martinez and LM Taussig (1991) Group Health Medical Associates. Relationship of parental smoking to wheezing and nonwheezing lower respiratory tract illnesses in infancy. J Pediatr 118 207-214.
204. B Alm, G Wennergren, SG Norvenius, et al. (2002) Breast feeding and the sudden infant death syndrome in Scandinavia, 1992-95. Arch Dis Child 86 400-402.
205. KL McVea, PD Turner and DK Peppler (2000) The role of breastfeeding in sudden infant death syndrome. J Hum Lact 16 13-20.
206. RE Gilbert, RE Wigfield, PJ Fleming, et al. (1995) Bottle feeding and the sudden infant death syndrome. BMJ 310 88-90.
207. FR Hauck, OO Omojokun and MS Siadaty (2005) Do pacifiers reduce the risk of sudden infant death syndrome? A meta-analysis. Pediatrics 116 e716-e723.
208. DK Li, M Willinger, DB Petitti, et al. (2006) Use of a dummy (pacifier) during sleep and risk of sudden infant death syndrome (SIDS): Population based case-control study. BMJ 332 18-22.
209. P Franco, S Scaillet, V Wermenbol, et al. (2000) The influence of a pacifier on infants’ arousals from sleep. J Pediatr 136 775-779.
210. CR Howard, FM Howard, B Lanphear, et al. (2003) Randomized clinical trial of pacifier use and bottle-feeding or cupfeeding and their effect on breastfeeding. Pediatrics 111 511-518.
211. EA Mitchell, PS Blaier and MP L'Hoir (2006) Should pacifiers be recommended to prevent sudden infant death syndrome? Pediatrics 117 1755-1758.
212. DG Talbert (1990) SIDS, surfactant, and temperature (letter). Lancet 336 690.
213. AN Stanton (1984) Overheating and cot death. Lancet ii 1199-1201.
214. PJ Fleming, R Gilbert, Y Azaz, et al. (1990) Interaction between bedding and sleeping position in the sudden infant death syndrome: A population based case-control study. BMJ 301 85-89.
215. AL Ponsonby, T Dwyer, L Gibbons, et al. (1992) Thermal environment and sudden infant death syndrome: Case-control study. BMJ 304 277-282.
216. AL Ponsonby, T Dwyer, LE Gibbons, et al. (1993) Factors potentiating the risk of sudden infant death syndrome associated with the prone position. N Engl J Med 329 377-382.
217. R Gilbert, P Rudd, PJ Berry, et al. (1992) Combined effect of infection and heavy wrapping on the risk of sudden unexpected infant death. Arch Dis Child 67 171-177.
218. D Berterottière, AM D'Allest, M Dehan and C Gaultier (1990) Effects of increase in body temperature in the breathing pattern in premature infants. J Dev Physiol 1990 13 303-308.
219. D Gozal, A Colin, YI Daskalovic and M Jaffe (1988) Environmental overheating as a cause of transient respiratory chemoreceptor dysfunction in an infant. Pediatrics 82 738-740.
220. RG Carpenter (1972) Sudden and unexplained deaths in infancy (cot death). FE Camps, RG Carpenter (Eds) Sudden and Unexpected Deaths in Infancy (cot death) Bristol: John Wright 7-15.
221. JJ McKenna and T McDade (2005) Why babies should never sleep alone: A review of the co-sleeping controversy in relation to SIDS, bedsharing and breast feeding. Paediatr Respir Rev 6 134-152.
222. D Tappin, H Brooke and R Ecob (2004) Bedsharing and sudden infant death syndrome (SIDS) in Scotland, UK. Lancet 363 994.
223. D Tappin, R Ecob and H Brooke (2005) Bedsharing, roomsharing, and sudden infant death syndrome in Scotland: A case-control study. J Pediatr 147 32-37.
224. H Abramson (1944) Accidental mechanical suffocation in infants. J Pediatr 25 494-513.
225. R Gilbert, G Salanti, M Harden and S See (2005) Infant sleeping position and the sudden infant death syndrome: Systematic review of observational studies and historical review of recommendations from 1940 to 2002. Int J Epidemiol 34 874-887.
226. MJ Wagaman, JG Shutack, AS Moomjian, et al. (1979) Improved oxygenation and lung compliance with prone positioning of neonates. J Pediatr 94 787-791.
227. TM Baird, JB Paton and DE Fisher (1991) Improved oxygenation with prone positioning in neonates: Stability of increased transcutaneous PO 2. J Perinatol 11 315-318.
228. SR Orenstein, AA Mitchell and S Davidson Ward (1993) Concerning the American Academy of Pediatrics Recommendation on sleep position for infants. Pediatrics 93 497-499.
229. CE Hunt and DC Shannon (1992) Sudden infant death syndrome and sleeping position. Pediatrics 90 115-118.
230. JMD Thompson, BT Thach, DMO Becroft and EA Mitchell (2006) Sudden infant death syndrome: Risk factors for infants found face down differ from other SIDS cases. J Pediatr 149 630-633.
231. CF Poets, A Rudolph, K Neuber, et al. (1995) Arterial oxygen saturation in infants at risk of sudden death: Influence of sleep position. Acta Paediatr 84 379-382.
232. T Ishikawa, S Isono, J Aiba, et al. (2002) Prone position increases collapsibility of the passive pharynx in infants and small children. Am J Respir Crit Care Med 166 760-764.
233. P Franco, A Pardou, S Hassid, et al. (1998) Auditory arousal thresholds are higher when infants sleep in the prone position. J Pediatr 132 240-243.
234. EA Mitchell, PG Tuohy, JM Brunt, et al. (1997) Risk factors for sudden infant death syndrome following the prevention campaign in New Zealand: A prospective study. Pediatrics 1997 100 835-840.
235. PJ Fleming, PS Blair, C Bacon, et al. (1996) Confidential Enquiry into Stillbirths and Deaths Regional Coordinators and Researchers. Environment of infants during sleep and risk of the sudden infant death syndrome: Results of 1993-5 case-control study for confidential enquiry into stillbirths and deaths in infancy. BMJ 313 191-195.
236. BT Skadberg, I Morild and T Markestad (1998) Abandoning prone sleeping: Effect on the risk of sudden infant death syndrome. J Pediatr 132 340-343.
237. EA Mitchell, BT Thach, JMD Thompson, S Williams and for the New Zealand Cot Death Study (1999) Changing infants’ sleep position increases risk of sudden infant death syndrome. Arch Pediatr Adolesc Med 153 1136-1141.
238. DA Paluszynska, KA Harris and BT Thach (2004) Influence of sleep position experience on ability of prone-sleeping infants to escape from asphyxiating microenvironments by changing head position. Pediatrics 114 1634-1639.
239. JE Haas, JA Taylor, AB Bergman, et al. (1993) Relationship between epidemiologic risk factors and clinicopathologic findings in the sudden infant death syndrome. Pediatrics 91 106-112.
240. JB Beckwith (1988) The mechanism of death in sudden infant death syndrome. JL Culbertson, HF Krous, RD Bendell (Eds) Sudden Infant Death Syndrome. Medical Aspects and Psychological Management Baltimore: Johns Hopkins University Press 48-61.
241. HF Krous and J Jordan (1988) A comparison of the distribution of petechiae and their significance in sudden infant death syndrome (SIDS), lethal upper airway obstruction and non-SIDS. RM Harper, HJ Hoffman (Eds) Sudden Infant Death Syndrome. Risk Factors and Basic Mechanisms New York: PMA 91-100.
242. CJ Campbell and DJC Read (1980) Circulatory and respiratory factors in the experimental production of lung petechiae and their possible significance in the sudden infant death syndrome. Pathology 12 181-188.
243. JP Farber, AC Catron and HF Krous (1983) Pulmonary petechiae: Ventilatory-circulatory interactions. Pediatr Res 17 230-233.
244. CP Handforth (1959) Sudden unexpected death in infancy. Can Med Assoc J 80 872-873.
245. WG Guntheroth (1973) The significance of pulmonary petechiae in crib death. Pediatrics 52 601-603.
246. WG Guntheroth (1983) The pathophysiology of petechiae. JT Tildon, LM Roeder, A Steinschneider (Eds) Sudden Infant Death Syndrome New York: Academic Press 271-278.
247. M Risse and G Weiler (1989) Vergleichende histologische Untersuchungen zur Genese petechialer Thymusblutungen. Z Rechtsmed 102 33-40.
248. TK Marshall (1970) Significance of petechiae. AB Bergmann, JB Beckwith, CG Ray (Eds) Sudden Infant Death Syndrome Seattle: University of Washington Press 122.
249. FE Camps (1972) Discussion. FE Camps, RG Carpenter (Eds) Sudden and Unexpected Deaths in Infancy (Cot Deaths) Bristol: Wright & Sons 71.
250. P Brouardel (1897) La Pendaison, la Strongulation, la Suffocation, la Submersion Paris: J.-B. Bailliere et Fils 20.
251. K Winn (1986) Similarities between lethal asphyxia in postneonatal rats and the terminal episode in SIDS. Pediatr Pathol 5 325-335.
252. JB Beckwith (1973) The sudden infant death syndrome. Curr Probl Pediatr 3 3-35.
253. FD Martinez (1991) Sudden infant death syndrome and small airway occlusion: Facts and a hypothesis. Pediatrics 87 190-198.
254. R Meadow (1999) Unnatural sudden infant death. Arch Dis Child 80 7-14.
255. DM Becroft, JM Thompson and EA Mitchell (2001) Nasal and intrapulmonary haemorrhage in sudden infant death syndrome. Arch Dis Child 85 116-120.
256. HF Krous, JM Nadeau, RW Byard and BD Blackbourne (2004) Oronasal blood in sudden infant death. Am J Forens Med Pathol 22 346-351.
257. E Tapp, DM Jones and JOH Tobin (1975) Interpretation of respiratory tract histology in cot deaths. J Clin Path 28 899-904.
258. AT Schäfer, R Lemke and H Althoff (1991) Airway resistance of the posterior nasal pathways in sudden infant death victims. Eur J Pediatr 150 595-598.
259. DR Telford, JA Morris, P Hughes, et al. (1989) The nasopharyngel bacterial flora in the sudden infant death syndrome. J Infect 18 125-130.
260. P Zink, J Drescher, W Verhagen, et al. (1987) Serological evidence of recent influenza virus A (H3N2) infections in forensic cases of the sudden infant death syndrome (SIDS). Arch Virol 93 223-232.
261. KD Forsyth, SC Weeks, L Koh, et al. (1989) Lung immunoglobulins in the sudden infant death syndrome. BMJ 298 23-26.
262. RL Naeye (1988) Sudden infant death syndrome, is the confusion ending? Modern Pathol 1 169-174.
263. M Valdes-Dapena (1988) Sudden infant death syndrome: Overview of recent research developments from a pediatric pathologist's perspective. Pediatrician 15 222-230.
264. JE Gillan, C Curran, E O'Reilly, et al. (1989) Abnormal patterns of pulmonary neuroendocrine cells in victims of sudden infant death syndrome. Pediatrics 84 828-834.
265. AK Haque, MG Mancuso, J Hokanson, et al. (1991) Bronchiolar wall changes in sudden infant death syndrome: Morphometric study of a new observation. Pediatr Pathol 11 551-568.
266. TO Rognum and OD Saugstad (1991) Hypoxanthine levels in vitreous humor: Evidence of hypoxia in most infants who died of sudden infant death syndrome. Pediatrics 87 306-310.
267. KL Jones, HF Krous, J Nadeau, et al. (2003) Vascular endothelial growth factor in the cerebrospinal fluid of infants who died of sudden infant death syndrome: Evidence for antecedent hypoxia. Pediatrics 111 358-363.
268. HC Kinney (2005) Abnormalities of the brainstem serotonergic system in the sudden infant death syndrome. A review. Pediatr Dev Pathol 5 507-524.
269. F Pena and JM Ramirez (2002) Endogenous activation of serotonin-2A receptors is required for respiratory rhythm generation in vitro. J Neurosci 22 11055-11064.
270. N Narita, M Narita, S Takashima, et al. (2001) Serotonin transporter gene variation is a risk factor for sudden infant death syndrome in the Japanese population. Pediatrics 107 690-692.
271. DE Weese-Mayer, L Zhou, EM Berry-Kravas, et al. (2003) Association of the serotonin transporter gene with sudden infant death syndrome. Am J Med Gen 122A 238-245.
272. SH Opdal and TO Rognum (2004) The sudden infant death syndrome gene: Does it exist? Pediatrics 114 e506-e512.
273. SH Opdal, A Opstad, A Vege and TO Rognum (2003) IL-10 gene polymorphisms are associated with infectious cause of sudden infant death. Hum Immunol 64 1183-1189.
274. DE Weese-Mayer, EM Berry-Kravis, L Zhou, et al. (2004) Sudden infant death syndrome: Case-control frequency differences at genes pertinent to early autonomic nervous system embryologic development. Pediatr Res 56 391-395.
275. DP Southall, JM Richards, M de Swiet, et al. (1983) Identification of infants destined to die unexpectedly during infancy: Evaluation of predictive importance of prolonged apnoea and disorders of cardiac rhythm or conduction. BMJ 286 1092-1096.
276. DP Southall, JM Richards, V Stebbens, et al. (1986) Cardiorespiratory function in 16 full-term infants with sudden infant death syndrome. Pediatrics 78 787-796.
277. VL Schechtman, RM Harper, AJ Wilson and DP Southall (1991) Sleep apnea in infants who succumb to the sudden infant death syndrome. Pediatrics 87 841-846.
278. AJ Wilson, V Stevens, CI Franks, et al. (1995) Respiratory and heart rate patterns in infants destined to be victims of sudden infant death syndrome: Average rates and their variability measured over 24 hours. BMJ 290 497-501.
279. DP Southall, V Stevens, CI Franks, et al. (1988) Sinus tachycardia in term infants preceding sudden infant death. Eur J Pediatr 147 74-78.
280. TB Waggener, DP Southall and LA Scott (1990) Analysis of breathing patterns in a prospective population of term infants does not predict susceptibility to sudden infant death syndrome. Pediatr Res 27 113-117.
281. KJ Antila, IAT Välimäki, M Mäkelä, et al. (1990) Heart rate variability in infants subsequently suffering sudden infant death syndrome (SIDS). Early Hum Dev 22 57-72.
282. KA Kluge, RM Harper, VL Schechtman, et al. (1988) Spectral analysis assessment of respiratory sinus arrhythmia in normal infants and infants who subsequently died of sudden infant death syndrome. Pediatr Res 24 677-682.
283. VL Schechtman, RM Harper, KA Kluge, et al. (1989) Heart rate variation in normal infants and victims of the sudden infant death syndrome. Early Hum Dev 19 167-181.
284. VL Schechtman, SL Raetz, RK Harper, et al. (1992) Dynamic analysis of cardiac R-R intervals in normal infants and in infants who subsequently succumbed to the sudden infant death syndrome. Pediatr Res 31 606-612.
285. VL Schechtman, RM Harper, AJ Wilson and DP Southall (1992) Sleep state organization in normal infants and victims of the sudden infant death syndrome. Pediatrics 89 865-870.
286. T Hashimoto, K Hiura, S Endo, et al. (1983) Postural effects on behavioral state of newborn infants. Brain Dev 5 286-291.
287. Y Brackbill, TC Douthitt and H West (1973) Psychophysiologic effects in the neonate of prone versus supine placement. J Pediatr 82 82-84.
288. I Kato, J Groswasser, P Franco, et al. (2001) Developmental characteristics of apnea in infants who succumb to sudden infant death syndrome. Am J Respir Crit Care Med 164 1464-1469.
289. DP Southall, WA Arrowsmith, JR Oakley, et al. (1979) Prolonged QT interval and cardiac arrhythmias in two neonates; sudden infant death syndrome in one case. Arch Dis Child 54 776-779.
290. PJ Schwartz (1987) The quest for the mechanisms of the sudden infant death syndrome: Doubts and progress. Circulation 75 677-683.
291. DP Southall, WA Arrowsmith, V Stebbens and JR Alexander (1986) QT interval measurements before sudden infant death syndrome. Arch Dis Child 61 327-333.
292. SL Weinstein and A Steinschneider (1985) QTc and R-R intervals in victims of the sudden infant death syndrome. Am J Dis Child 139 987-990.
293. PJ Schwartz, M Stramba-Badiale, A Segantini, et al. (1998) Prolongation of the QT interval and the sudden infant death syndrome. N Engl J Med 338 1174-1709.
294. JF Lucey (1999) Comments on a sudden infant death article in another journal. Pediatrics 103 812-820.
295. H Wedekind, T Bajanowski, P Friederich, et al. (2005) Sudden infant death syndrome and long QT syndrome: An epidemiological and genetic study. Int J Legal Med 13 1-9.
296. M Christiansen, N Tonder, LA Larsen, et al. (2005) Mutations in the HERG K+-ion channel: A novel link between long QT syndrome and sudden infant death syndrome. Am J Cardiol 95 433-434.
297. JR Skinner (2005) Is there a relation between SIDS and long QT syndrome? Arch Dis Child 90 445-449.
298. RG Meny, JL Carroll, MT Carbone and DH Kelly (1994) Cardiorespiratory recordings from infants dying suddenly and unexpectedly at home. Pediatrics 93 44-49.
299. RG Meny, A Jesurun, CH Lin and JE Smialek (1996) SIDS is not always sudden. J SIDS Infant Mortality 1 51-54.
300. DH Kelly, A Pathak and R Meny (1991) Sudden severe bradycardia in infancy. Pediatr Pulmonol 10 199-204.
301. CF Poets, RG Meny, MR Chobanian and RE Bonofiglo (1999) Gasping and other cardiorespiratory patterns during sudden infant death. Pediatr Res 45 350-354.
302. R Sridhar, BT Thach, DH Kelly and JA Henslee (2003) Characterization of successful and failed autoresuscitation in human infants, including those dying of SIDS. Pediatr Pulmonol 36 113-122.
303. WG Guntheroth and I Kawabori (1975) Hypoxic apnea and gasping. J Clin Invest 56 1371-1377.
304. American Academy of Pediatrics Task Force on Sudden Infant Death Syndrome (2005) The changing concept of sudden infant death syndrome: Diagnostic coding shifts, controversies regarding the sleeping environment, and new variables to consider in reducing risk. Pediatrics 116 1245-1255.
305. P Blair, MP Ward Platt, IJ Smith and PJ Fleming (2006) Sudden infant death syndrome and sleeping position in pre-term and low birthweight infants: An opportunity for targeted intervention. Arch Dis Child 91 101-106.
306. PF Stastny, TY Ichinose, SD Thayer, et al. (2004) Infant sleep positioning by nursery staff and mothers in newborn hospital nurseries. Nurs Res 53 122-129.
307. Hoffman HJ, Damus K, Krongrad E, Hillman L: Apnea, birth weight, and SIDS: Results of the NICHD cooperative epidemiological study of sudden infant death syndrome (SIDS) risk factors. In U.S. Department of Health and Human Services (eds): Infantile Apnea and Home Monitoring. Bethesda, NIH Publication No 87-2905, B53-B69, 1987.
308. N Marlow, LP Hunt and ML Chiswick (1988) Clinical factors associated with adverse outcome for babies weighing 2000 g or less at birth. Arch Dis Child 63 1131-1136.
309. CF Poets (2001) The role of monitoring. RW Byard, HF Krous (Eds) Sudden Infant Death Syndrome—problems, progress and possibilities London: Arnold 236-242.
310. A Kahn, D Blum, P Hennart, et al. (1984) A critical comparison of the history of sudden-death infants and infants hospitalised for near-miss for SIDS. Eur J Pediatr 143 103-107.
311. U Kiechl-Kohlendorfer, D Hof, UP Peglow, et al. (2005) Epidemiology of apparent life threatening events. Arch Dis Child 90 297-300.
312. A Steinschneider (1972) Prolonged apnea and the sudden infant death syndrome: Clinical and laboratory observations. Pediatrics 50 646-654.
313. AB Bergman, JB Beckwith and CG Ray (1975) The apnea monitor business. Pediatrics 56 1-3.
314. R Firstman and J Talan (1997) The death of innocents New York: Bantam Books
315. GA Little and JG Brooks (1994) Accepting the unthinkable. Pediatrics 94 748-749.
316. DP Southall, RE Janczynski, JR Alexander, et al. (1990) Cardiorespiratory patterns in infants presenting with apparent life-threatening episodes. Biol Neonate 57 77-87.
317. J Oren, DH Kelly and DC Shannon (1989) Pneumogram recordings in infants resuscitated for apnea of infancy. Pediatrics 83 364-368.
318. AL van der Hal, AM Rodriguez, CW Sargent, et al. (1985) Hypoxic and hypercapneic arousal responses and prediction of subsequent apnea in apnea of infancy. Pediatrics 75 848-854.
319. S Coons and C Guilleminault (1985) Motility and arousal in near miss sudden infant death syndrome. J Pediatr 107 728-732.
320. KW Lewis and EM Bosque (1995) Deficient hypoxia awakening response in infants of smoking mothers: Possible relationship to sudden infant death syndrome. J Pediatr 127 691-699.
321. P Franco, S Scaillet, V Wermenbol, et al. (2000) The influence of a pacifier on infants’ arousals from sleep. J Pediatr 136 775-779.
322. P Franco, A Pardou, S Hassid, et al. (1998) Auditory arousal thresholds are higher when infants sleep in the prone position. J Pediatr 132 240-243.
323. CF Poets, MP Samuels and DP Southall (1992) The potential role of intrapulmonary shunting in the pathogenesis of hypoxemic episodes in infants and young children. Pediatrics 90 385-392.
324. DP Southall, MP Samuels and DG Talbert (1990) Recurrent cyanotic episodes with severe arterial hypoxaemia and intrapulmonary shunting: A mechanism for sudden death. Arch Dis Child 65 953-961.
325. MJ Wilkinson and DG Fagan (1990) Intrapulmonary arteriovenous shunting: A mechanism in sudden unexpected death. Arch Dis Child 65 435-437.
326. DP Southall, MP Samuels and CF Poets (1992) Prolonged expiratory apnea and intrapulmonary shunting. B Beckerman, B Brouillette, CE Hunt (Eds) Respiratory Control Disorders in Infants and Children Baltimore: Williams & Wilkins 242-251.
327. LC Kao and TG Keens (1985) Decreased specific airway conductance in infant apnea. Pediatrics 76 232-235.
328. H Hartmann, J Seidenberg, JP Noyes, et al. (1998) Small airway patency in infants with apparent life-threatening events. Eur J Pediatr 157 71-74.
329. JJ Herbst, LS Brook and PF Bray (1978) Gastroesophageal reflux in the “near miss” sudden infant death syndrome. J Pediatr 92 73-75.
330. G Wennergren, T Hertzberg, J Milerad, et al. (1989) Hypoxia reinforces laryngeal reflex bradycardia in infants. Acta Paediatr Scand 78 11-17.
331. SR Orenstein and DM Orenstein (1998) Gastroesophageal reflux and respiratory disease in children. J Pediatr 112 847-858.
332. JK Walsh, MK Farrell, WJ Keenan, et al. (1981) Gastroesophageal reflux in infants: Relation to apnea. J Pediatr 99 197-201.
333. SJ Newell, IW Booth, MEI Morgan, et al. (1989) Gastro-oesophageal reflux in preterm infants. Arch Dis Child 64 780-786.
334. A Kahn, E Rebuffat, M Sottiaux, et al. (1990) Sleep apneas and acid esophageal reflux in control infants and in infants with apparent life-threatening events. Biol Neonate 57 144-149.
335. JY Paton, CS Nanayakkara and H Simpson (1990) Observations on gastro-oesophageal reflux, central apnoea and heart rate in infants. Eur J Pediatr 149 608-612.
336. JY Paton, U Macfadyen, A Williams and H Simpson (1990) Gastro-oesophageal reflux and apnoeic pauses during sleep in infancy—no direct relation. Eur J Pediatr 149 680-686.
337. M de Ajuriaguerra, MF Radvanyi-Bouvet, C Huon and G Moriette (1991) Gastroesophageal reflux and apnea in prematurely born infants during wakefulness and sleep. Am J Dis Child 145 1132-1136.
338. G Veereman-Wauters, A Bochner and M van Caillie-Bertrand (1991) Gastroesophageal reflux in infants with a history of near-miss sudden infant death. J Pediatr Gastroenterol Nutrition 12 319-323.
339. CC See, LJ Newman, S Berezin, et al. (1989) Gastroeosophageal reflux-induced hypoxemia in infants with apparent life-threatening event(s). Am J Dis Child 143 951-954.
340. CF Poets, MP Samuels, JP Noyes, et al. (1993) Home event recordings of oxygenation, breathing movements and electrocardiogram in infants and young children with recurrent apparent life-threatening events. J Pediatr 123 693-701.
341. J Hewertson, CF Poets, MP Samuels, et al. (1994) Epileptic seizure-induced hypoxemia in infants with apparent life-threatening events. Pediatrics 94 148-156.
342. MP Samuels, W McClaughlin, RR Jacobson, et al. (1992) Fourteen cases of imposed upper airway obstruction. Arch Dis Child 67 162-170.
343. DP Southall, MCB Plunkett, MW Banks, et al. (1997) Covert video recordings of life-threatening child abuse: Lessons for child protection. Pediatrics 100 735-760.
344. A Kahn and European Society for the Study and Prevention of Infant Death (2004) Recommended clinical evaluation of infants with an apparent life-threatening event. Consensus document of the European Society for the Study and Prevention of Infant Death, 2003. Eur J Pediatr 163 108-115.
345. G Wennergren, J Milerad, H Lagercrantz, et al. (1987) The epidemiology of sudden infant death syndrome and attacks of lifelessness in Sweden. Acta Paediatr Scand 76 898-906.