Screening and identification of novel B cell epitopes in human heparanase and their anti-invasion property for hepatocellular carcinoma

Cancer Immunology, Immunotherapy

Volumn 58, Issue 9, 2009, Pages 1387-1396

  Yang, Jian Min ^a   Wang, Hui Ju ^a   Du, Ling ^b   Han, Xiao Mei ^b   Ye, Zai Yuan ^a   Fang, Yong ^c   Tao, Hou Quan ^a   Zhao, Zhong Sheng ^a   Zhou, Yong Lie ^a  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

B cell epitopes; Epitope identification; Heparanase; Hepatocellular carcinoma; Immunogenicity

Indexed keywords

EPITOPE; HEPARANASE; INTERLEUKIN 1BETA; MULTIPLE ANTIGENIC PEPTIDE 1; MULTIPLE ANTIGENIC PEPTIDE 2; MULTIPLE ANTIGENIC PEPTIDE 3; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG; VALYLGLUTAMINYLGLYCYLGLUTAMYLGLUTAMYLSERYLASPARAGINYLASPARTYLLYSINE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CANCER CELL CULTURE; CANCER INVASION; CULTURE MEDIUM; HUMAN; HUMAN CELL; IMMUNOGENICITY; LIVER CELL CARCINOMA; MALE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RABBIT; SEQUENCE ANALYSIS;

ANIMALS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL ADHESION; CELL CYCLE; CELL MOVEMENT; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES, B-LYMPHOCYTE; FLOW CYTOMETRY; GLUCURONIDASE; HUMANS; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS; MALE; PEPTIDE FRAGMENTS; RABBITS;

EID: 67649657510     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-008-0651-x     Document Type: Article

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