Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen

Veterinary Microbiology

Volumn 118, Issue 3-4, 2006, Pages 201-211

  Dechamma, H J ^a   Dighe, V ^b   Kumar, C Ashok ^a   Singh, R P ^a   Jagadish, M ^a   Kumar, Satish ^b  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Antipeptide antibody; Diagnosis; Peste des petits ruminants; T helper epitope

Indexed keywords

AMINO ACID; EPITOPE; INTERLEUKIN 1BETA; NUCLEOCAPSID PROTEIN; VIRUS ANTIGEN;

ALGORITHM; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN BINDING; ANTIGEN SPECIFICITY; ANTIGENICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPUTER AIDED DESIGN; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELPER CELL; IMMUNIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; BLOTTING, WESTERN; COMPLEMENTARITY DETERMINING REGIONS; DIAGNOSIS, DIFFERENTIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; FEMALE; INTERLEUKIN-1BETA; NUCLEOCAPSID PROTEINS; PESTE-DES-PETITS-RUMINANTS; PESTE-DES-PETITS-RUMINANTS VIRUS; RABBITS; RANDOM ALLOCATION; RINDERPEST; RINDERPEST VIRUS; SENSITIVITY AND SPECIFICITY;

PESTE-DES-PETITS-RUMINANTS VIRUS; REINDEER PAPILLOMAVIRUS;

EID: 33751216857     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2006.07.023     Document Type: Article

References (28)

1. Antoni G.R., Presentini F., Perin A., Tagliabue P., Ghiara S., Censini G., et al. A short synthetic peptide fragment of human interleukin-1 with immunostimulatory but not inflammatory activity. J. Immunol. 137 (1986) 3201
2. Atherton E., and Sheppard R.C. In: Rickwood D., and Hames B.D. (Eds). Solid Phase Peptide Synthesis: Practical Approach (1989), IRL Press, Oxford
3. Barrett T., Visser I.K., Mamaev L., Goatley M.F., and Van Osterhaus B. Osterhaus, dolphin and porpoise morbilliviruses are genetically distinct from phocine distemper virus. Virology 193 (1993) 1010-1012
4. Beckers W., Villa L., Gonfloni S., Castagnoli L., Newton S.M., Cesareni G., and Ghiara P. Increasing the immunogenicity of protein antigens through the genetic insertion of VQGEESNDK sequence of humal IL-1β into their sequence. J. Immunol. 151 (1993) 1757-1764
5. Brattegaard K., Soroh D., Zadi F., Digbeu H., Vetter K.M., and De Cock K.M. Insensitivity of a synthetic peptide based test (Pepti-Lav 1-2) for the diagnosis of HIV infection in African children. AIDS 9 (1995) 656-657
6. Buckland R., Giraudon P., and Wild F. Expression of measles virus nucleoprotein in E. coli: use of deletion mutants to locate the antigenic sites. J. Gen. Virol. 70 (1989) 435-441
7. Choi K.S., Nah J.J., Choi C.U., Ko Y.J., Sohn H.J., libeau G., Kang S.Y., and Joo Y.S. Monoclonal antibody based competitive ELISA for simultaneous detection of rinderpest virus and peste des petits ruminants virus antibodies. Vet. Microbiol. 96 (2003) 1-16
8. Choi K.S., Nah J.J., Ko Y.J., Kang S.Y., Yoon K.J., and Joo Y.S. Characterization of immunodominant linear B-cell epitopes on the carboxy-terminus of the rinderpest virus nucleocapsid protein. Clin. Diagn. Lab. Immunol. 11 (2004) 658-664
9. Diallo A., Barret T., Lefevre P.C., and Taylor W.P. Comparison of proteins induced in cells infected with rinderpest and pestes des petits ruminants virus. J. Gen. Virol. 68 (1987) 2033-2038
10. Diallo A., Barrett T., Barbron M., Meyer G., and Lefevre P.C. Cloning of nucleocapsid protein gene of peste des petits ruminants virus. J. Gen. Virol. 75 (1994) 233-237
11. Gibbs E.J.P., Taylor W.P., Lawman M.J.P., et al. Classification of peste des petits ruminants virus as the fourth member of the genus Morbillivirus. Intervirology 11 (1979) 268-274
12. Giraudon P., Buckland R., and Wild T.F. The immune response to measles virus in mice: T-helper response to the nucleoprotein and mapping of the T-helper epitopes. Virus Res. 22 (1991) 41-54
13. Hickman C.J., Khan A.S., Rota P.A., and Bellini W.J. Use of synthetic peptides to identify measles nucleoprotein T-cell epitopes in vaccinated and naturally infected humans. Virology 235 (1997) 386-397
14. Hoyland J.A., Dixon J.A., Berry J.L., Davies M., Selby P.L., and Mee A.P. A comparison of in situ hybridization reverse transriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection of canine distemper virus RNA in Raget's disease. J. Virol. Meth. 109 (2003) 253-259
15. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
16. Libeau G., Prehaud C., Lancelot R., Colas F., Guerre L., Bishop D.H.L., and Diallo A. Development of a competitive ELISA for detecting antibodies to the peste des petits ruminants virus using a recombinant nucleoprotein. Res. Vet. Sci. 58 (1995) 50-55
17. Lin R., Tarr P.E., and Jones T.C. Present status of the use of cytokines as adjuvants with vaccines to protect against infectious diseases. Clin. Inf. Dis. 21 (1995) 1439-1449
18. Marttila J., Ilonen J., Norrby E., and Salmi A. Characterization of T cell epitopes in measles virus nucleoprotein. J. Gen. Virol. 80 (1999) 1609-1615
19. Ohisi K., Kamata H., Yamanouchi K., and Barrett T. Identification of T-helper cell epitopes in the hypervariable region of the nucleocapsid (N) protein of RPV in cattle. Vaccine 18 (2000) 3077-3081
20. Pau C.P., Holloman D.L., Lee-Thomas S., Schochetmam G., and George J.R. A combination immunoblot for the simultaneous detection and differentiation of HIV-1 and HIV-2. Clin. Diagn. Virol. 1 (2000) 201-205
21. Peter K., and Chou P.P. Comparing tandem repeats and multiple antigenic peptides as the antigens to detect antibodies by enzyme immunoassay. J. Immunol. Meth. 257 (2001) 51-54
22. Rudensky A.Y., Hurlburt P.P., Hong S.C., Barlow A., and Janeway C.A. Sequence analysis of peptides bound to MHC class II molecules. Nature (London) 353 (1991) 622-627
23. Schirle M., Toni W., and Stefan S. Combining computer algorithms with experimental approaches permits the rapid and accurate identification of T cell epitopes from defined antigens. J. Immunol. Meth. 257 (2001) 1-16
24. Shao H.J., Chen L., and Su Y.B. DNA fragment encoding human IL-β 163-171 peptide enhances the immune responses elicited in mice by DNA vaccine against foot and mouth disease. Vet. Res. Commun. 29 (2005) 35-46
25. Sreenivasa B.P., Dhar P., Singh R.P., and Bandyopadhyay S.K. Evaluation of an indigenously developed homologous live-attenuated cell culture vaccine against peste des petits ruminants infection of small ruminants. Proceedings of the 20th Annual Conference of Indian Association of Veterinary Microbiologists, Immunologists and Specialists in Infestious Diseases and National Symposium on trends in Vaccinology for Animal Diseases. India (2000)
26. Syu W.J., and Kahan L. Characterization of antigenic structures by mapping on resin-bound epitope analogs. Meth. Enzyme 203 (1991) 295-300
27. Taylor W.P. The distribution and epidemiology of peste des petits ruminants. Prev. Vet. Med. 2 (1984) 157-166
28. Viscidi R.P., Hill P.M., Li S.J., Cerny E.H., Vlahov D., Farzadegan H., et al. Diagnosis and differentiation of HTLV-1 and HTLV-II infection by enzyme immunoassays using synthetic peptides. J. Acq. Immun. Def. Synd. 4 (1991) 1190-1198