메뉴 건너뛰기




Volumn 19, Issue 5, 2008, Pages 465-468

Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

ARGATROBAN; FIBRINOGEN; HIRULOG; LEPIRUDIN; MUTANT PROTEIN; PROTEIN C; THROMBIN; THROMBOMODULIN;

EID: 67649532171     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e328304e044     Document Type: Letter
Times cited : (3)

References (13)
  • 1
    • 0034704118 scopus 로고    scopus 로고
    • Rational design of a potent anticoagulant thrombin
    • Cantwell AM, Di Cera E. Rational design of a potent anticoagulant thrombin. J Biol Chem 2000; 275:39827-39830.
    • (2000) J Biol Chem , vol.275 , pp. 39827-39830
    • Cantwell, A.M.1    Di Cera, E.2
  • 2
    • 0037008668 scopus 로고    scopus 로고
    • The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo
    • Gruber A, Cantwell AM, Di Cera E, Hanson SR. The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo. J Biol Chem 2002; 277:27581-27584.
    • (2002) J Biol Chem , vol.277 , pp. 27581-27584
    • Gruber, A.1    Cantwell, A.M.2    Di Cera, E.3    Hanson, S.R.4
  • 3
    • 4544312894 scopus 로고    scopus 로고
    • The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket
    • Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, et al. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem 2004; 279:39824-39828.
    • (2004) J Biol Chem , vol.279 , pp. 39824-39828
    • Pineda, A.O.1    Chen, Z.W.2    Caccia, S.3    Cantwell, A.M.4    Savvides, S.N.5    Waksman, G.6
  • 4
    • 0030707669 scopus 로고    scopus 로고
    • The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis
    • Elg M, Gustafsson D, Deinum J. The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis. Thromb Haemost 1997; 78:1286-1292.
    • (1997) Thromb Haemost , vol.78 , pp. 1286-1292
    • Elg, M.1    Gustafsson, D.2    Deinum, J.3
  • 6
    • 2442509800 scopus 로고    scopus 로고
    • Predicting the pharmacology of thrombin inhibitors
    • Adams TE, Everse SJ, Mann KG. Predicting the pharmacology of thrombin inhibitors. J Thromb Haemost 2003; 1:1024-1027.
    • (2003) J Thromb Haemost , vol.1 , pp. 1024-1027
    • Adams, T.E.1    Everse, S.J.2    Mann, K.G.3
  • 7
    • 0037438708 scopus 로고    scopus 로고
    • Dissecting substrate recognition by thrombin using the inactive mutant S195A
    • Krem MM, Di Cera E. Dissecting substrate recognition by thrombin using the inactive mutant S195A. Biophys Chem 2003; 100:315-323.
    • (2003) Biophys Chem , vol.100 , pp. 315-323
    • Krem, M.M.1    Di Cera, E.2
  • 8
    • 2942627502 scopus 로고    scopus 로고
    • A critical role for thrombin in platelet aggregation under high shear stress
    • Sakurai Y, Shima M, Giddings J, Takeyama M, Kasuda S, Nogami K, et al. A critical role for thrombin in platelet aggregation under high shear stress. Thromb Res 2004; 113:311-318.
    • (2004) Thromb Res , vol.113 , pp. 311-318
    • Sakurai, Y.1    Shima, M.2    Giddings, J.3    Takeyama, M.4    Kasuda, S.5    Nogami, K.6
  • 9
    • 0035816595 scopus 로고    scopus 로고
    • An extensive interaction interface between thrombin and factor V is required for factor V activation
    • Myles T, Yun TH, Hall SW, Leung LL. An extensive interaction interface between thrombin and factor V is required for factor V activation. J Biol Chem 2001; 276:25143-25149.
    • (2001) J Biol Chem , vol.276 , pp. 25143-25149
    • Myles, T.1    Yun, T.H.2    Hall, S.W.3    Leung, L.L.4
  • 10
    • 1842647532 scopus 로고    scopus 로고
    • Inhibition of thrombin-induced feedback activation of factor V: A potential pathway for inhibition of thrombin generation by melagatran
    • Bostrom SL, Dagnelid E, Hansson GFH, Ulvinge C. Inhibition of thrombin-induced feedback activation of factor V: a potential pathway for inhibition of thrombin generation by melagatran. Blood Coagul Fibrinolysis 2004; 15:25-30.
    • (2004) Blood Coagul Fibrinolysis , vol.15 , pp. 25-30
    • Bostrom, S.L.1    Dagnelid, E.2    Hansson, G.F.H.3    Ulvinge, C.4
  • 12
    • 33744781844 scopus 로고    scopus 로고
    • The effect of aprotinin on activated protein C-mediated downregulation of endogenous thrombin generation
    • Tanaka KA, Szlam F, Levy JH. The effect of aprotinin on activated protein C-mediated downregulation of endogenous thrombin generation. Br J Haematol 2006; 134:77-82.
    • (2006) Br J Haematol , vol.134 , pp. 77-82
    • Tanaka, K.A.1    Szlam, F.2    Levy, J.H.3
  • 13
    • 6444239394 scopus 로고    scopus 로고
    • The effects of argatroban on thrombin generation and hemostatic activation in vitro
    • Tanaka K, Szlam F, Katori N, Sato N, Vega J, Levy J. The effects of argatroban on thrombin generation and hemostatic activation in vitro. Anesth Analg 2004; 99:1283-1289.
    • (2004) Anesth Analg , vol.99 , pp. 1283-1289
    • Tanaka, K.1    Szlam, F.2    Katori, N.3    Sato, N.4    Vega, J.5    Levy, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.